mydrugbuddy
Bluelighter
Shit dude, thats rough. Play nice with these ones!
yeah it sounds like you're damaging your body. It'll take a bit of a hammering, but it needs a rest njow and then (i know that's fuckin rich coming from me hahha~)
Shit dude, thats rough. Play nice with these ones!
The scientist behind synthetic cannabis says the products ''absolutely should not be used as recreational drugs''.
Emeritus Prof John W. Huffman, of South Carolina, developed synthetic cannabinoid compounds that bear his initials (such as JWH-018 and JWH-073) in his laboratory more than 15 years ago.
Those compounds were widely discussed in scientific publications, and ''evidently some people have figured out how to make them and are putting them in products''.
The compounds were ''not meant for human consumption'', he said.
''Their effects in humans have not been studied and they could very well have toxic effects. They absolutely should not be used as recreational drugs.''
Prof Huffman, an organic chemist at Clemson University, said the compounds which are appearing in ''fake marijuana'' products were among many created by his group, and others, during research supported by the National Institute on Drug Abuse between 1984 and 2010.
That research aimed to understand the relationship between the chemical structure and the biological activity of substances known as cannabinoids.
Cannabinoids include THC - the active ingredient in cannabis plants - but also other substances that interact with the cannabinoid receptors in the brain and other organs, he said.
''These receptors don't exist so that people can smoke marijuana and get high; they play a role in regulating appetite, nausea, mood, pain and inflammation.''
The receptors could be involved in the development of conditions such as osteoporosis, liver disease and some kinds of cancer, Prof Huffman said.
''Synthetic cannabinoids can help us understand these interactions and, ultimately, this knowledge may contribute to the development of new therapies.
''Again, I would emphasise the risk people are taking when they smoke these products. We simply don't know what the health effects might be.''
I think what got me so fucked is that the stuff melts to your gauze when you smoke with a pipe. The liquid remainder hardens on the gauze and also inside the pipe where it dripped. When you add more powder later, the powder burns & so does the left over congealed liquid from last time - suddenly you're smoking more than you realised.
^ Total BULLSHIT.
1. The 'reverse isomer' of THC is a dissociative? You have refs to back that up, because to the best of my knowledge the only cannabinoid that has significant and distinct differences in pharmacological effects between isomers is HU-210\HU-211, which has some striking changes compared to THC.
2. "Many synthetic cannabinoids affect the NMDA receptor" where the FUCK are you getting this information?
3. "Synthetic cannabinoids affect....the 5HT system" AGAIN...TOTAL SPECULATION.
4. The only true thing in your ENTIRE post is that synthetic cannabinoids are less studied than the 'noids in marijuana, which kind of contradicts all of your fabricated info anyway.
You can't just represent your opinions as facts, man, that's fucked up, especially for someone calling other people "liar".
By the way, since smoking marijuana involves combusting material with an open flame, and inhaling tar, it is very easily considered that synthetics are safer than marijuana when used responsibly(unless you are vaping or eating your weed, then you break even).
How can you say that when the safety of neither weed nor synthetic cannabinoids has been sufficiently studied? I'd say every argument can be made.
Please would you quote where I said this. Also note my use of the word "likely".
To be honest, I'm not quite sure why I said that. But was it really worth objecting? It was a thought I had at the time that imo was worth sharing.
To recap what I said earlier, I was saying that just because weed is natural and synthetic cannabinoids are, well, synthetic, it doesn't mean that weed is safe and synthetic cannabinoids are dangerous. Nowhere did I claim that weed is dangerous and synthetic cannabinoids are safe. What I did say, however, was that weed is more likely to be dangerous statistically because it is made up of hundreds of cannabinoids. I think this is a reasonable claim. Also remember that weed is made up of more things than cannabinoids, meaning the risk of weed containing a dangerous substance is even higher. And most people smoke it with tobacco anyway, which quite frankly is a massive LOL to the argument that smoking weed is safe.
I'm not dissing weed; I'm dissing other people dissing synthetics.
Finally, whether a cannabinoid is naturally occurring or synthetically made is completely irrelevant.
First time poster. Anyone know where I can get a good legal alternative to weed in the UK online?