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Opioids Oxycodone to Morphine Conversion question

B

butters!

Greenlighter
Joined
Mar 22, 2012
Messages
12
hello all, if it takes 180mg of oxy to get off how much morphine sulphate er does it take for like results?
 
270mg according to here



EDIT: Fuck, I misread your post. That's for oral administration, but you can calculate most ROAs from that site.
 
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270mg of morphine seems like alot....i wouldn't take over 100 mg. you can always start low and work youre way up until you get desired effects. Better safe than sorry bub.
 
I depends on route, but orally that conversion is reasonable. When swapping I went from 60mg of oxy to 90mg of morphine and notice comparable effects. This was the prescribed conversion. I agree that 270mg is alot, but 180mg of oxy is a hell of a lot too so it's not surprising...
 
It seems like a lot because to a lot of people it is a lot. However, with the tolerance stated, 100mg of morphine would be a total waste. If you really want to be safe, start with your oxy dose and go up from there. Morphine has shit oral BA, so it's going to require a lot via that ROA.



EDIT: I misread the OP and thought it was oral admin for some reason.
 
Moderator Note: WITH ALL DUE RESPECT TO THOSE READING THIS, IM NOT SAYING THAT ANYONE IN THIS THREAD IS GUILTY OF THIS BUT IT'S A REOCCURRING ISSUE THAT I WILL LIKELY AMEND TO THE OD GUIDELINES IN THE FUTURE:ED. THANK YOU.-Team OD
... and I DID! so here they are:

BECAUSE IT'S A REOCCURRING ISSUE, I HAVE AMENDED THE OD GUIDELINES AS FOLLOWS, SO TO AVOID INFRACTIONS AND BANS WHERE APPROPRIATE PLEASE NOTE THE FOLLOWING:

Attention those of you who are giving advice on dosages particularly when calculating an equipotent dose between opioids (or all drugs in general, for example also when comparing benzodiazepine equivalency, it is very important that you consider the following before posting dosing advice


PLEASE DO NOT GIVE ADVICE IF YOU ARE USING A NARCOTIC CONVERTER AS YOUR ONLY GUIDE (I.E. WITHOUT HAVING FIRST HAND EXPERIENCE) AS THEY DO NOT FACTOR IN THE FACT THAT EVERY INDIVIDUAL HAS UNIQUE BODY CHEMISTRY NOT TO MENTION THE VERY HIGH LIKELIHOOD THAT USERS/ORIGINAL POSTERS HERE ASKING FOR DOSE CONVERSIONS ARE ALREADY TOLERANT TO ONE OR MORE OF THE DRUGS THEY INCLUDE WHEN ATTEMPTING TO DESCRIBE THEIR TOLERANCE/BACKGROUND, AND THEIR INTENTIONS WITH THE (PRESUMABLY) FOREIGN/NEW/UNFAMILIAR MEDICATION.

ROUTE OF ADMINISTRATION PLAYS A HUGE ROLE, FOR EXAMPLE, A COMMON ISSUE IS ASSESSING THE POTENCY OF MORPHINE VS OXYCODONE. MORPHINE IS MORE THAN TWICE AS POTENT AS OXYCODONE WHEN TAKEN INTRAVENOUSLY. OXYMORPHONE IS EXPONENTIALLY MORE POTENT VIA THE IV ROA COMPARED TO THE ORAL ROA....THEREFORE IT'S IMPORTANT TO REMEMBER.....

NARCOTIC CONVERTERS DO NOT FACTOR IN TOLERANCE, AND THE HIGH VARIABILITY OF CROSS-TOLERANCE REQUIRES DOSAGE CONVERSIONS TO BE PERFORMED ON A PERSONALIZED CASE BY CASE BASIS.

ONE SIZE DOES NOT FIT ALL AND BECAUSE THESE ARE NUMBERS THAT PEOPLE ARE WILLING TO BET THEIR LIVES ON, WE ARE ASKING FOR THOSE OF YOU WHO DO NOT ACTUALLY HAVE EXPERIENCE WITH THE DRUGS OR THE TOPIC AT HAND, AND / OR OTHERWISE ARE NOT TOTALLY COMPETENT THAT THE ANSWER / DOSE CONVERSION THAT YOU CALCULATED AND ARE CONSIDERING POSTING, TRIPLE CHECK THAT YOUR ADVICE WON'T END IN A FATALITY.....WE ARE ASKING YOU TO REFRAIN FROM GIVING DOSING ADVICE DUE TO THE OBVIOUS HR PROBLEM INVOLVED. THANK YOU.-Team OD
Click to expand...

@OP, what is your tolerance to oxycodone? How do you usually take oxycodone? Do you take OP OxyContin via the oral route of administration? Do you inject roxicodone? Do you snort roxicodone? We need to determine your individual and unique tolerance before we can give you an accurate enough dose advice that we can all feel comfortable about.

I know you say 180mg, but it really makes a difference how you ingest that 180mg before I can safely recommend to you a similar dosage of morphine. We also will need to know how you intend to ingest the morphine.

The reason this is so important is that oxycodone, provided your an IV user, oxycodone is less than half as potent as morphine when injected. This means that if for example, you shoot 180mg oxycodone in one shot, the amount you would need in IV morphine to replicate the same effects would be LESS THAN HALF of 180mg.

In this hypothetical situation if you were shooting 180mg oxy IR at a time, I would advise to you that you begin with shooting 60mg of morphine (DEPENDING ON WHAT FORM OF MORPHINE YOU ARE GOING TO BE WORKING WITH, THIS IS ALSO CRITICAL TO OUR ANSWER TO YOUR QUESTION. WHAT FORM OF MORPHINE WILL YOU BE WORKING WITH? THE IMPRINT ON THE PILL WILL TELL US ALL WE NEED TO KNOW EXCEPT FOR HOW OLD THE MORPHINE YOU HAVE IS. IT COULD BE EXPIRED FOR ALL WE KNOW).

Granted, I doubt you shoot 180mg per shot, I'm guessing you do 180mg oxycodone over the course of the day, and I am not even sure why I'm assuming that you inject the oxycodone, as oxycodone is one of the LEAST suitable opioids to inject especially when done without utilizing proper proactive sterile harm reduction techniques.... so.....

How do you ingest that total of 180mg of Oxycodone? If your taking 6 x 30mg Roxicodone (oxycodone IR), it makes a big difference compared to taking 3 x 60mg OxyContin, for example, or 6 x 30mg OxyContin.

How do you plan on ingesting the morphine? It's more than twice as strong as oxycodone when injected, that's why I wanted to bring up the topic of injecting even though the OP didn't mention it, in case they were to try injecting 270mg morphine as per the first replies recommendation, which was clearly intended to be taken orally, again I'm assuming.
 
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In my experience I've found when used both are used orally, oxycodone is approx. 1.5 times as strong as morphine, and when both are used IV morphine is twice the strength of oxycodone
 
For me, orally 30mg of oxycodone IR feels like 60-90mg of oral morphine IR

But I am an opioid tolerant chronic pain patient, so others respond differently. Most of my friends agree with oxycodone being 2x potent mg for mg as oral morphine.
 
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