• N&PD Moderators: Skorpio

5-br-DMT

5-Br-indigo is well known, there is a tryptophan bromination enzyme in some sea animals I think.

I believe 5-F-DMT is known and possibly active. Not sure about the higher halogens. There's no reason to believe it *wouldn't* be active at binding serotonin receptors; there may be some question as to whether or not it's a full agonist, partial agonist or antagonist though. I think Cl is closer to MeO in terms of size anyway?

Also, I know there is at least 1 erowid reference for some sort of psychedelic fish that is active when orally ingested? Nature is wierd.
 
It says right in the article that extraction is not a realistic route. It would take kilos of sponge material to produce a single dose, which is not "economically or ecologically viable". The total synthesis is relatively easy though.
 
5-Br-indigo is well known, there is a tryptophan bromination enzyme in some sea animals I think.

I believe 5-F-DMT is known and possibly active. Not sure about the higher halogens. There's no reason to believe it *wouldn't* be active at binding serotonin receptors; there may be some question as to whether or not it's a full agonist, partial agonist or antagonist though. I think Cl is closer to MeO in terms of size anyway?

Also, I know there is at least 1 erowid reference for some sort of psychedelic fish that is active when orally ingested? Nature is wierd.
There is at least 3 that come to my mind if you include ordeal(hallucination) prefacing death, but looking at wikipedia there are a few hallucinogenic and thousands of venomous fish
http://en.wikipedia.org/wiki/Ichthyoallyeinotoxism
http://en.wikipedia.org/wiki/Venomous_fish

Information aside, I tragically am narrowing down suspect individuals published as Osculum, but I guess it can never actually be referenced directly.
Probably a hyperbaric breathing session would make me feel better.
I guess it can never actually be referenced directly.
stoked about ultimate recreational numinous experience with aquatic entities, possibly autonomous from biology(half kidding) but otherwise leveling with the sponge, sizing each other up from chimney to osculum
 
Whoa, pretty cool find! I read about this awhile back and just assumed it was probably bufotenin, DMT, or 5-MeO-DMT, but a novel tryptamine... pretty awesome find! Opens up a door of possibilities :)

5-Br-indigo is well known, there is a tryptophan bromination enzyme in some sea animals I think.

I believe 5-F-DMT is known and possibly active. Not sure about the higher halogens. There's no reason to believe it *wouldn't* be active at binding serotonin receptors; there may be some question as to whether or not it's a full agonist, partial agonist or antagonist though. I think Cl is closer to MeO in terms of size anyway?

Also, I know there is at least 1 erowid reference for some sort of psychedelic fish that is active when orally ingested? Nature is wierd.

5-Br-Indigo? Do you mean 5-Br-indole? Indane? Indene?
 
The stuff they dye blue jeans with, a blue-purple pigment from e.g. woad that is called indigo.

wiki said:
Tyrian purple is a dull purple dye that is secreted by a common Mediterranean snail. It was highly prized in antiquity. In 1909 its structure was shown to be 6,6'-dibromoindigo.
 
Copied from a reddit comment:

I have tried this. It provided a thorough stoning effect, with the only visuals produced being colour saturation and mild waving or breathing, like a low dose of mushrooms or something, and that was at its most intense part. Its just nice an relaxing, and very smooth but light. This is not a breakthrough intensity experience like plain DMT or 5-MeO-DMT. I loaded around 50-65(?) mg into a pipe and shared it with two other friends, (this is a guess I didnt actually measure it because I knew its effects were very light and going too far is pretty difficult).

Worth a try, and it doesn't exhaust you very much. You are totally functional and we were able to city bus down to a restaurant for a beer part way through the experience.
 
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