Opioids Asian Opiate Withdrawal Pills

[pema]

There are some Asian opiate withdrawal capsules/pills. Nearly all of them completely herbal origin. Mainly from China. But some from Vietnam, Korea, Cambodia.
Some of them were also discussed in some drug forums and actually it seemed that some of them really helped (e.g. Chinese formula).

There are:
- Chinsese Formula (Chinese herbal medicine. positive effects reported by users in drug forums)
- Crave Control
- STOP Formula
- U'Finer (Chinese herbal medicine. positive clinical trials exist)
- Tai-Kang-Ning (Chinese herbal medicine. positive clinical trials exist)
- WeiniCom (AKA Xuan Xia Detoxification Formula) (Chinese herbal medicine. positive clinical trials exist)
- Heantos (developed by a vietnamese herbalist. shall cure heroin addiction in 3 days. maybe some patients died. should be tested by UN program)
- Cademex
- Bong Sen (a lot of articles in the news because addicts where forced by Cambodian government to take it in "voluntary" trials)
- Fu-Yuan Pellet
- Shenfu Tuodu
- Fukang Pian
- Shifu Sheng
- Keduning
- Junfukang
- Jinniu (probably not especially for detox but there is a clinical study that compared this capsules with lofexidine for opiate detox)
- Qingfeng (maybe a sedative which was given to addicts)
- Mentat (not especially for detox but there is a study that it help for deaddiction purpose, too)

Some of them were sold as wonder drugs but have not shown great effects. But there were some deaths linked to those pills.
But there are also some preparates that really helped. I read a long discussion in an other drug forum about The Chinese Formula and it really helped some people to reduce opiate withdrawal symptoms.
There were clinical studies on at least Xuan Xi (Weinicom), U'Finer and Tai-Kang-Ning that proved that this stuff may be useful to treat opiate addiction.

I tried to get as much information about these withdrawal preparations as possible.
This is not easy. Some information is only in Chinese and I can't read that.
And although I could find some clinical studies on medline, it was not possible to find a list of the ingredients to some preparates.
Or for other preparations all I could find was the ingredient list and no information on the effect, no studies, no nothing.

Has anybody some information on these preparations? (I know that some ingredient lists were posted in some forums.) I already found some studies (mainly on medline). But if somebody knows about other studies, trials, ...
Any interessting news paper articles? Interessting discussions in drug forums that I haven't found maybe?
I'm glad about every link and every piece of information.



BTW: There are also some US American detox formulas. I found at least two of them: Withdrawal-Ease and Withdrawal Relief Complex. It's expensive and I don't think that it will help a lot. Unfortunately there is nearly no information to find. All experience reports I could find, were located on the vendor's websites. So maybe they wrote it by themselves. No reports of users who tried on any internet forum.
I wouldn't sacrifice my money for that stuff and probably no other addict, too. That's probably the cause for no experience reports on internet forums. But the vendors seem to spend really big amounts of money for advertisement. So I think, somebody must buy this stuff. Why no internet discussions on that stuff? It seems that nobody has tried it.
And there are no clinical/scientific/medical trials/studies although one vendor claims that they sell their stuff to withdrawal clinics.
Any information on those pseudo-medicaments?

 

[Seattle_Stranger]

Very interesting stuff...

I wonder if any of these preparations use kratom as an ingredient...

 

[Jabberwocky]

^+1 Seconded. Although I am very skeptical of natural remedies, especially those with claims as strong as being able to significantly ease w/d, it would be wonderful if some effective ones actually existed. I mean, there is lots of herbs/chems that make withdrawal infinitely easier, in some cases nearly painless. Still, I'm still left wonderful whether stuff like this is nothing more than snake oil salesman garbage.

 

[TheLostBoys]

If a scientist or doctor ever came out with a pill/concoction that could ease withdrawals & the user wouldnt feel much pain, etc......that person would become a millionaire overnight.

 

[tricomb]

Reckitt Beckinser would be pisssssed.

 

[Ninjetic]

Karma

This thread just gave me the inspiration to do something
But I've got a plan, and its gonna help a lot of people
That's saying something cuz I've always been a bit of an asshole around here but I think I'm gonna go to college now to be a scientist or doctor to make the cure, I know I can yping on touchscreen

 

[Miss Kirsty]

Is it just me or do a few of them sound like jokes?

Fukang Pian = Fucking pain

Junfukang = Mid year fuck

WeiniCom = smalldickcom

Soz....Im in a stupid mood...OP..Apologies...

 

[muie]

The strongest would have to be knockdafuggoutt or facefuckasiancumswallow

 

[lenses]

Xuan Xui (weinicom) is awesome . It is a very drying, warming herb. I take a dose (500-1000 mgs a dose) and you feel your veins dilating again and warmth coming back to your skin. Dare I say it even feels, pleasant? I took a 10 day course of it, and the only side effects is some sedation from doses over 500mgs... Kept me about 80% out of withdrawl. I was suprised.

Corydalis (Yan Hu Suo) is in a bunch of these asian opiate addiction pills. From my understanding it seems to be a dopamine blocker , with THP(tetrahydropalmatine) being the main ingredient. Keeps the sympathetic nervous system calmed down.

There are also some obscure opiate receptor ligands , with affinity for delta and kappa receptors...

I also like nigella sativa oil.Delta opioid receptor agonist I believe...

Quit a few year long suboxone habit with those xuan xui and nigella sativa oil alone. I tapered down to 1 mg. My withdrawl effects were very minor. The nigella oil really seems to score points for your brain in terms of getting back to normal... I was dosing the oil when I was still taking suboxone, made the effects much stronger, and when I stopped the bupe it seemed like I was withdrawing from a much minor amount. Usually the game is something like sweats->coldness->nausea->diarrea->anxiety->tiredness ,in that order, roughly. The nigella sativa oil put me straight to the end, where I am just dealing with some minor fatigue.

-lenses

 

[FnX]

This eerily reminds me of a time when people were smoking "herbal blends" without knowing that they were actually putting research chemicals in those blends. "It's the synergy man". Don't take me wrong, I'm not here trying to debunk the herbs themselves, these days I would just REALLY hesitate taking surprisingly effective herbal capsules that originate from china.

 

[FlawedByDesign]

Corydalis (Yan Hu Suo) is in a bunch of these asian opiate addiction pills. From my understanding it seems to be a dopamine blocker , with THP(tetrahydropalmatine) being the main ingredient. Keeps the sympathetic nervous system calmed down.

I found levo-tetrahydropalmatine to be quite useful for combating insomnia and RLS during withdrawls

 

[lenses]

This eerily reminds me of a time when people were smoking "herbal blends" without knowing that they were actually putting research chemicals in those blends. "It's the synergy man". Don't take me wrong, I'm not here trying to debunk the herbs themselves, these days I would just REALLY hesitate taking surprisingly effective herbal capsules that originate from china.

The formulas I got a hold of were compounded according to traditional chinese medicine practices, i don't think any weird chem labs in china are throwing research chems in these blends... I think the biggest thing to worry about with herbals is heavy metal contamination. I imagine you are thinking of some of the "secret asian happy miracle cures" that were tested and found to have methadone in them LOL.I bet they worked well.

One of the other names for the traditional glaucine+THP combo is "yellow bells", and i'm fairly sure its a formula thats been around for a few hundred years.

Anything that I have to take for10 days to get off the opiate cycle with out having to complete have my mind torn down, is cool with me.

Last time I kicked suboxone cold turkey it was a very bad withdrawl that was 14 days of bed sweating, puking, terror.

There are a lot of viable opiate withdrawl drugs out there that people aren't aware of. 5HT3 antagonists (ginger is a minor one) I hear are amazing for withdrawl, cutting out almost all gastro-intestinal badness.Ondansetron is the pharmaceutial standard.

Anything that works like clonidine , things related to oxymetazoline... very good too. I think theres a lot of mechanism of action similarities in the xuan xui formula.

-lenses

 

[tricomb]

^I'll vouch for ondansetron.

 

[Swimmingdancer]

Xuan Xui (weinicom) is awesome .

Xuan Xia?

It (WeiniCom / Xuan Xia) is listed as containing Corydalis rhizome (not sure what species), Cordyalis decumbentis rhizome, Shisandra berry (not sure what species, likely Schisandra chinensis), Gastrodiae rhizome (likely Gastrodia elata), Astragalus root, Cordyceps (presumably Cordyceps sinensis), Chaunxing rhizome (Ligusticum chuanxiong Hort., aka Szechuan lovage root), Codonopsis root (presumably Codonopsis pilosula), Panax quinquonosides, "etc" (whatever "etc" means). These are all plants that have been used in Chinese medicine for a very long time.

From a double-blind study on WeiniCom comparing it to buprenorphine:

Both the WeiniCom and buprenorphine treatments are well-tolerated and very safe. Overall, the relief from opioid withdrawal symptoms and craving was better in the WeiniCom group than in the buprenorphine group. The rate of reduction in the severity of the withdrawal symptoms was faster in the WeiniCom group than in the buprenorphine group. By day nine to 10, the WeiniCom group showed very few withdrawal symptoms. In contrast, from day five on, the buprenorphine group continued to report relatively high scores for withdrawal symptoms and craving. WeiniCom demonstrated positive effects quickly, and required a shorter treatment period to achieve a desired degree of elimination of acute withdrawal symptoms and craving. [source]

Related reading: Clinical Trial of WeiniCom in Heroin Detox

---

Some of these herbal withdrawal treatments do sound very promising. Unfortunately, many herbal treatments have poorly described pharmacokinetics, the variability in ingredients inherent in anything naturally sourced, unknown or poorly understood mechanisms of action, a lack of supporting data derived from numerous/large well-controlled clinical trials, sometimes an unknown potential for toxicity, and - most of all - are not likely to make pharmaceutical companies big profits. Therefore, it's impossible to expect widespread acceptance of their use in the management of opioid dependence and the fact that they are not well-known (at least not outside Asia) does not mean they are not effective. Personally my main fear would be that something that works well could be dependence-causing itself and merely postponing withdrawal. I'm going to ask a Chinese herbalist about some of these

Edit: Just realized the OP was a year old but this subject is very interesting to me so I'm glad someone bumped the thread

 

[amanitadine]

Xuan xia used to contain Kratom, not sure if it still does.

And the "Chinese formula" early on was adulterated with methadone IIRC.

No wonder these buggers help just sayin'.

Who knows what they contain now. . .

 

[RedRum OG]

My guess as to what's in 90% of these pills

1) tea
2) yard clippings (or is the phrase -trimmings?)
3) kratom

P.s. the only things that you can put in your mouth to ease opiate withdrawals are opiates and strong placebos

 

[FnX]

Xuan Xia?

From a double-blind study on WeiniCom comparing it to buprenorphine:

Related reading: Clinical Trial of WeiniCom in Heroin Detox

---

Some of these herbal withdrawal treatments do sound very promising. Unfortunately, many herbal treatments have poorly described pharmacokinetics, the variability in ingredients inherent in anything naturally sourced, unknown or poorly understood mechanisms of action, a lack of supporting data derived from numerous/large well-controlled clinical trials, sometimes an unknown potential for toxicity, and - most of all - are not likely to make pharmaceutical companies big profits. Therefore, it's impossible to expect widespread acceptance of their use in the management of opioid dependence and the fact that they are not well-known (at least not outside Asia) does not mean they are not effective. Personally my main fear would be that something that works well could be dependence-causing itself and merely postponing withdrawal. I'm going to ask a Chinese herbalist about some of these

This sounds really odd to me, wouldn't you think that opiate replacement therapy was vastly more effective at reducing withdrawal symptoms and craving than any non-opiate/opioid herbal remedy? Almost too good to be true.

EDIT: Terrible quoting from me, sorry, the comment above is meant for the tandfonline.com link.

 

[Swimmingdancer]

This sounds really odd to me, wouldn't you think that opiate replacement therapy was vastly more effective at reducing withdrawal symptoms and craving than any non-opiate/opioid herbal remedy? Almost too good to be true.

EDIT: Terrible quoting from me, sorry, the comment above is meant for the tandfonline.com link.

It's not your fault, when you quote someone it removes any parts of their post that were in quotes. One thing about the study is that I can't see what doses of each were used, or for how long. But buprenorphine is a partial agonist/antagonist and it's very common for people to still not feel very well for the first week or so after switching from a full agonist like heroin, so it isn't all that implausible. I wish I could read the full paper. I'll see what other info I can dig up on WeiniCom.

That study comparing it to bupe was published in the Journal of Psychoactive Drugs, which is a US peer-reviewed journal FWIW.

Xuan xia used to contain Kratom, not sure if it still does.

Real Xuan Xia / WeiniCom is not supposed to contain any kratom or any other opioids. Since the authentic Chinese Xuan Xia has restrictions in the US (I believe it's because one of the herbs is banned in the US and they want to undergo approval as a drug as opposed to as a herbal supplement - surprise surprise), a US vendor marketed a product that they promoted as "Xuan Xia", which replaced the Cordyalis (one of the most important ingredients in real Xuan Xia / WeiniCom) with kratom. Kratom is not used in traditional Chinese medicine AFAIK. So it's important to know what you're getting. But honestly I don't know if one can even really get real WeiniCom in the West.

lenses - Do you know what was in the Xuan Xia you used? And when you stopped taking it did you get any withdrawal symptoms?

the only things that you can put in your mouth to ease opiate withdrawals are opiates and strong placebos

That is definitely not true. Nothing magically makes opiate WD 100% better of course but there are plenty of things that can make a significant difference - there are tons of threads and megathreads about drugs and herbs and things that help with opioid withdrawal that are not opioids themselves (and there have been numerous carefully-controlled studies done on many drugs which proves it isn't just placebo). Personally I'm thrilled with anything that helps.

 

[MaybeHad2Much2fast]

I found levo-tetrahydropalmatine to be quite useful for combating insomnia and RLS during withdrawls

Hmm ive never heard of that is it a supplement available at vitamin stores? i've got a withdrawal coming here soon and i was wondering if its readily available in the states?

 

[lenses]

Real Xuan Xia / WeiniCom is not supposed to contain any kratom or any other opioids. Since the authentic Chinese Xuan Xia has restrictions in the US (I believe it's because one of the herbs is banned in the US and they want to undergo approval as a drug as opposed to as a herbal supplement - surprise surprise), a US vendor marketed a product that they promoted as "Xuan Xia", which replaced the Cordyalis (one of the most important ingredients in real Xuan Xia / WeiniCom) with kratom. Kratom is not used in traditional Chinese medicine AFAIK. So it's important to know what you're getting. But honestly I don't know if one can even really get real WeiniCom in the West.

lenses - Do you know what was in the Xuan Xia you used? And when you stopped taking it did you get any withdrawal symptoms?

Yeah swimmingdancer- There is a "full" Xuan Xia / WeiniCom list that isn't published online due to that FDA stupidness with the cordyalis... I respect the company enough to not post the list in a public forum.

Quitting the xuan xia isn't a big deal. Towards the end your body starts feeling rejuvenated, and there are NO withdrawl symptoms. If there are, you should still be taking it. It seems to bring your brain back to a state of balance...

It's not the same one on the website. It definitely does NOT have any kratom in it. I am very familiar with kratom. This doesn't feel like an opiate. There are a LOT of things that go towards making this formula work well, there are immune enhancing herbs (astragalus's), some bronchiodilators, some sedatives,some analgesics ,and some things for the stomach like licorish root.

Those asians, they know a lot about opiates. They dealt with opiate addiction for thousands of years! Ya know, you go with the cultures who have experience.

Don't underestimate the nigella sativa oil.You would expect arabic culture to have some sort of opiate withdrawl remedys due to the 'heron culture and poppy fields. The structure of thymoquinone is very similar to menthol(weak kappa agonist).

This presentation has some very good information.

-lenses