Opioids Roxicodone 30mg ir

[A2Z&NBETWEEN]

I smoke roxi all the time. which pill is strongest, which is worst. opinions about iv use? <snip>

most commentary regarding roxi30 instant release is appreciated

 

[bapae]

Swim, and price disscusion aren't aloud here.

and what do you mean by which is strongest?

I wouldn't say any pill is worse then another, but no pill is best, and they should definatly find another ROA other then smoking them, the fillers and binders are terrible for your lungs, either take then orally by swallowing, plug then rectally, or take them nasally.

 

[macd610]

Swim, and price disscusion aren't aloud here.

and what do you mean by which is strongest?

I wouldn't say any pill is worse then another, but no pill is best, and they should definatly find another ROA other then smoking them, the fillers and binders are terrible for your lungs, either take then orally by swallowing, plug then rectally, or take them nasally.

I agree. Please don't use swim...it offers no protection of any kind and makes a post difficult to read.
Cat

 

[tricomb]

I smoke roxi all the time. which pill is strongest, which is worst. opinions about iv use? <snip>

most commentary regarding roxi30 instant release is appreciated

first of all, welcome to bluelight. before you do anything else, read the BLUA and the OD guidelines because you are violating multiple rules, no big deal your new here, but you agreed to read and abide by these rules upon creation of your account.

1) what do you mean by which pill is strongest??? That's one of the most vaguest questions I've ever seen asked here. Are you asking about how Oxycodone Hydrochloride is supplied? that's what I will answer since that question is way too vague and could be extended to many much more potent CNS active drugs.

(5, 10, 15, 20, 30mg Instant Release) (10, 15, 20, 30, 40, 60, 80mg Controlled Release). The strongest commercial formulation of instant release oxycodone hcl in the USA is the 30mg IR. The "strongest" Extended Release (biphasic 12-hour time release) commercial formulation would be the 80mgs, most commonly known as OP 80s.

2) Which is worst? This is even vaguer. Not sure how to answer this. But I know that what is worst for you is SMOKING PHARMACEUTICALS. They have these things in them, you know like besides the oxycodone, they are called inactive ingredients, and some of them are incredibly dangerous to smoke.

Not to mention that SMOKING OXYCODONE IS HORRIBLY INEFFICIENT. Don't even bother replying with "but I get high as fuck" or whatever variation, because most of it is placebo and what isn't, isn't worth the bodily harm you are causing. Have you ever heard of Emphysema? COPD? Cancer? I bet you get these real quick smoking pills.

3) Again, about routes of administration, oxycodone is best absorbed orally. It has a peak bioavailability of 87% (meaning taken orally, 87% of the oxycodone will reach your bloodstream, this figure doubles, triples or easily quadruples the amount you receive by smoking roxis), reportedly even higher with a high-fat meal according to some pubmed articles but that's another story. Point being, these pills, ESPECIALLY ROXICODONES were DESIGNED to hit the hardest via the oral route.

By IVing oxycodone, you achieve ZERO rush, ZERO advantages to oral administration, a SHORTER duration, all you achieve is risking tons of complications of intravenous drug abuse, not to mention your injecting with roxicodones, if my memory serves, the % of active ingredient to inactive ingredients/fillers/binders ratio should be alarming. The negligible BA gain one might achieve by shooting oxycodone is negated by the shorter duration and horrible health consequences, ESPECIALLY if the person has not been educated on what they are doing and applies heat while preparing the solution like they saw on TV on intervention or in the movies or w/e. *facepalm*

4) Other commentary: Nasal administration is also a waste of time because while it may feel like it hits harder at first due to increased onset, the amount of oxycodone that actually ends up reaching your bloodstream through your nose is less than HALF the concentrations of oxycodone when taken via the oral ROA.

The rectal ROA: okay, the basics... Plugging instant release oxycodone (and the old formulation ERs) is a viable alternative to the oral ROA in many circumstances, offering the same if not better amount of oxycodone absorbed compared to the oral ROA, but the rectal ROA has the advantage of RAPID onset and prolonged duration, especially of analgesia, which really matters if your a chronic pain patient, which you're obviously not because you smoke roxicodone.

Oxycodone HCl IR is VERY water soluble, like above 1.5 grams / mL if I remember correctly, (not like any of you should EVER be using that much oxycodone [1500mg... you'd have some serious issues])

If you REALLY want the best possible oxycodone absorption rectally, *ACCORDING TO THE PHARMACEUTICAL COMPANIES* its best absorbed when slowly administered (I'd say at a rate of 5mL over 1-2-3seconds post insertion, then hold the syringe in place for another 1-2-3 seconds JUST inside the sphincter, like 4cm in JUST barely enough to ensure there will be no leakage, so apply some pressure while administering if necessary, then remove and properly dispose of the syringe).

If your not down to plug, that's fine, but It's the only other viable alternative ROA of oxycodone and you asked, so you received an answer. However, you should SERIOUSLY at LEAST switch to the oral ROA. Seriously I bet if you tried oral dosing you would never go back to smoking that bullshit.

 

[A2Z&NBETWEEN]

you made me feel absolete lol, but you are very knowledgeable and i appreciate the great consideration. i will def. consider your advice and spread your knowledge to my clique... harm reduction 101

 

[tricomb]

do your part n spread the word yo, *CODONE drugs should be taken ORALLY. No exception. Unless you're okay with rectal admin, which offers some pros over oral as well as some cons some might argue but Also, for those who insist on banging no matter what for whatever illogical reasons, applying heat to IV shots is a big NO NO. "AS NOT SEEN ON TV."

Pills require MICRON filtration if you're going to bang them anyways, make sure you get a good 0.2um filter and maybe a 1.2um prefilter, it will run you a minimal amount of $ but well worth not dying a slow painful death later as a result of your drug use today, as well as the price of not being an idiot. can't put a price on that

 

[mrflowers00]

IMO shooting oxy is totally worth it if you don't heat it and micron filter it

 

[bapae]

IMO shooting oxy is totally worth it if you don't heat it and micron filter it

Don't condone IVing any substance please.

 

[oxyschottin]

I disagree with there being no rush from iv oxy. There is actually quite an enjoyable rush. Although it is nothing compared to morphine based opiates. There are also several downsides to Iv oxy such as ime very quick tolerance increase, and obviously risk of addiction. Please if you don't already iv don't start. Its a rough road to travel down.

 

[shimazu]

4) Other commentary: Nasal administration is also a waste of time because while it may feel like it hits harder at first due to increased onset, the amount of oxycodone that actually ends up reaching your bloodstream through your nose is less than HALF the concentrations of oxycodone when taken via the oral ROA.

I think you are shrugging that factor off too easily. Not everyone has 1-1.5 hours to wait to get high after already waiting x amount of hours. I tend to agree with you, but I also see why people snort them.

There is a noticeable difference in onset time, and by the time you get to the final legs you are usually so fucked up you cant even spell Body Absorption. Not everyone cares about that extra 20% or whatever number you want to throw out because if you were super serious about BA you'd advise people to just jump to IV heroin every time.

I liked to split mine and pop one half and rail the other usually

but yeah smoking is by far the dumbest route to go, and a waste of time and money imo

 

[hatrix]

IMO shooting oxy is totally worth it if you don't heat it and micron filter it

This is strictly against the rules. No suggesting IV drug use. Have fun with your infraction or warning.

I think you are shrugging that factor off too easily. Not everyone has 1-1.5 hours to wait to get high after already waiting x amount of hours. I tend to agree with you, but I also see why people snort them.

There is a noticeable difference in onset time, and by the time you get to the final legs you are usually so fucked up you cant even spell Body Absorption. Not everyone cares about that extra 20% or whatever number you want to throw out because if you were super serious about BA you'd advise people to just jump to IV heroin every time.

Not really, no. The BA of when insufflating is probably ~50% MAYBE. This is because your nose becomes caked in the fillers and binders, and leaves no room for the actual oxycodone. It's a complete and total waste. Instead of being a drug fiend and having no patience, take the pill orally and you will get much higher. Yea, onset takes 30-40 min, but you aren't completely wasting half of your pill. There's no reason to be so impatient unless you're about to go into some sort of withdrawal. Seeing as high the BA of oral is around 90%, no I don't think he's going to go and recommend IV. The extra 10% won't make much difference, but the difference between snorting it and taking it orally is rather huge. You're just wrong.

 

[shimazu]

this is from Bluelight itself

Oxycodone: Oral 60-87%; intranasal- 55-70%

http://www.bluelight.ru/vb/threads/266339-Bioavailability-Half-life-MEGA-Thread

so im not sure what kind of message you guys are trying to send here.

bottom line is, IDGAF about BA if im waiting on something I just want it asap.

probably gonna zonk out by the time you hit the last two-three hour window anyway tbh

and again, I tend to agree with the oral route but to just write off snorting as a waste is wrong in my book

 

[oxyschottin]

The reason people recommend Iv is becuz of the immediate onset of the high. And regardless if its 10 percent more ba. 10 percent is 10 percent. Once again I wouldn't suggest it unless someone is already on that road. But IME orally takes 30 min + to absorb and the high isn't as noticeable as snorting or Iv . But I will Iv opiates every time due to the fact that ik I'm getting 100 percent of the drug. But, to each his own.

 

[kwhat]

well if you are smoking your opiates then roxi30s r they way to go as in strongest since i dont believe theres not going to be an easy way to extract oxymorphone and convert its salt form for smoking

 

[HighonLife]

This is strictly against the rules. No suggesting IV drug use. Have fun with your infraction or warning.

The guy didnt suggest it, he just said it is worth it

and no this is not against the rules, BL is a HR website, so we dont take the approach of telling people just say "no" to drugs or ROAs. we give people information n suggestions as to how people should do what they are already planning to do in the least harmful way possible. should people iv pills? no. but despite that fact some will still do so and as mr flowers said if you're goin to dont heat the pills, thats HR advice right there, pills should also be micron filtered but atleast he mentioned not adding heat

Instead of being a drug fiend and having no patience,.

i would argue that this ^ is more of what BL is not about. looking down n judging someone because they are perhaps addicted to something.

im not saying people should IV and im definately not telling people its ok to IV pills but dont come around here saying BL is here to help people with certain ROAs but not others, THATS WRONG

EDIT: rethinkin my post, BL actually does have a history of telling people not to smoke pills as a ROA, perhaps thats cuz of how bad it is for the user n perhaps it is because there arent a whole lotta of ways people know of to reduce the harm in smoking pills, its just bad for you and i dunno many ways in which one could lessen the harm of that particular ROA, sure BL doesnt encourage people to IV there drugs because that wouldnt be HR, but for those who already do IV, BL is here to help them do that in the safest way possible

 

[Tryptamino]

always take your 'codones orally

 

[Mr.Scagnattie]

The guy didnt suggest it, he just said it is worth it

and no this is not against the rules, BL is a HR website, so we dont take the approach of telling people just say "no" to drugs or ROAs. we give people information n suggestions as to how people should do what they are already planning to do in the least harmful way possible. should people iv pills? no. but despite that fact some will still do so and as mr flowers said if you're goin to dont heat the pills, thats HR advice right there, pills should also be micron filtered but atleast he mentioned not adding heat





i would argue that this ^ is more of what BL is not about. looking down n judging someone because they are perhaps addicted to something.

im not saying people should IV and im definately not telling people its ok to IV pills but dont come around here saying BL is here to help people with certain ROAs but not others, THATS WRONG

EDIT: rethinkin my post, BL actually does have a history of telling people not to smoke pills as a ROA, perhaps thats cuz of how bad it is for the user n perhaps it is because there arent a whole lotta of ways people know of to reduce the harm in smoking pills, its just bad for you and i dunno many ways in which one could lessen the harm of that particular ROA, sure BL doesnt encourage people to IV there drugs because that wouldnt be HR, but for those who already do IV, BL is here to help them do that in the safest way possible

Yeah we aren't here to flat out tell anybody what to do or not to do... but we do encourage safer ROA's and discourage less safe ones, but the key being that we try to do it as unbiased as we can, presenting all the facts and not preaching to anybody our own definition of right and wrong.

 

[BlueberryfishY]

Yeah that's true but i thought IHOP was open 24/7? or is that waffle house?

Screw McDonalds man unless it's for breakfast, have you seen the new fish bites they have? nasty as hell.

 

[mrflowers00]

just reiterating i did say to micron filter pills

 

[tricomb]

this is from Bluelight itself
http://www.bluelight.ru/vb/threads/266339-Bioavailability-Half-life-MEGA-Thread
so im not sure what kind of message you guys are trying to send here.

bottom line is, IDGAF about BA if im waiting on something I just want it asap.

probably gonna zonk out by the time you hit the last two-three hour window anyway tbh

and again, I tend to agree with the oral route but to just write off snorting as a waste is wrong in my book

My anti-nasal stance is simply on the basis that most users/addicts/members/readers here are literally just crushing and snorting that lovely blue (or green if you dare... seriously, the 15s reaaally should be taken orally IMO) powder... Yeah I know what it's like, it's not like I would talk down on something I've done and enjoyed thoroughly socially, but that was a long time ago when I thought that it was a higher priority to use the nasal ROA because it was "socially acceptable" but IMO it just glorifies drug abuse, an act that while we as addicts may enjoy an aspect of, is not really something I see as being a fun way to interact with my friends. You need instant onset sometimes? I can feel that. That's when I administer it rectally with a tiny 5mL syringe, the whole prepping and administration process can be done anywhere you require a shred of privacy to snort or shoot a drug. My priorities today are with reducing any potential harm that might limit my future, I know how scary it can be to imagine considering your life from a different perspective than the usual just taking things day by day, living in the now, or whatever, but there are some potentially really serious long-term health consequences involved here, (pulmonary edema, emobolism, COPD, who knows, maybe systemic organ failure.) and widely, they are not taken seriously enough.

It's as close to instantaneous onset as I could ask for. Yeah, mr.flowers00 is right, I COULD shoot it, but the whole reason I'm plugging it in the first place and not snorting shooting or smoking or w/e is because I am trying to get the most out of what I have WITHOUT causing long-term damage to my entire body by IVing or to my nose, sinuses, trachea, and respiratory tract by snorting crushed roxicodone because I couldn't wait the 45 seconds it takes me to prep the 5ml solution for rectal administration, a process which is "in and out" in the remaining 15 seconds, so yeah, I can wait a grand total of 60 seconds (and another 120 seconds to wash my hands as onset hits you, a great time for one to look in the mirror and be reassured yet again by the pupil constriction by the time I've cleaned up everything and disposed of the syringe) to get IME/IMO an exponentially better experience by plugging it.

But to each his own. The reason I like the rectal ROA is because I think I am causing the least bodily harm and it provides a longer duration of analgesia compared to the oral, IV, IN, etc routes, I draw comparisons to similar phenomenon with rectal morphine and it's extremely surprisingly long duration over all other ROAs without requiring an extended-release system like pharmaceutical pills, patches, depots, etc. And the perks I've mentioned previously, rapid onset comparable to IV, the closest thing to a "rush" one might ever hope to achieve administering oxycodone systemically. Overall, past experience with IV oxycodone pales in comparison to overall experiences the IR ROA.

I don't require near-immediate onset frequently, I take my medication orally I'd say about 85% of the time. Because I, and others like me, don't have to worry about fucking up my nose any further (if you've used the intranasal ROA quite a bit in the past/present...), we don't have to worry about any IV-related risks like contracting hepatitis, HIV, MSRA, etc, or getting an abscess, or having to spend extra money on microns to be safe if I were to insist on injecting drugs when money is already obviously tight to go to "such lengths" to get the most out of the medication.

TL;DR The problem I have with the nasal ROA is not the BA%. If you have the luxury of being able to afford enough medication to make up for it, that's all great and fine, The HR issue here is that snorting crushed pills is not good for you long-term, and neither is shooting pills, micron'd or not. We really don't need to go into the specifics or post sources/literature to prove it. The inactive ingredients cause problems later on. And I'm concerned for your respiratory and cardiovascular systems.

From all the peer-reviewed articles I've read, I would HIGHLY suggest that you put your oxycodone into solution (oxy is SO soluble, you could use like 0.5-1mL of clean water/saline) if you insist upon intranasal administration, and look into using a nasal spray/mister type deal, as that's how they are getting the best results in the professional/medical/scientific setting, which you ALL should be shooting for to minimize harm, (the pubmed article I read earlier said with the oxycodone nasal spray they had a mean BA of like 46% +/- 34%). The same article goes on to say that the nasal ROA could be a viable ROA to oral and IV oxycodone but that it's extremely unpredictable/variable BA)
http://www.ncbi.nlm.nih.gov/pubmed/9062618

My Simple math: oral ba: 87% near complete absorption, least health consequences, 2nd best duration ROA in my experience.
My Simple logic: rectal BA: variable but up to the same if not higher than oral BA, fastest onset I need medically, longest duration "most bang for buck", less health consequences than common Intravenous / Intranasal techniques for administration of crushed oxycodone tablets, like injecting/inhaling particles of insoluble inactive ingredients mainlined and / or deep into my lungs with no way of expelling them.

My $0.02: telling people that it's great to inject or snort roxicodone and leaving them no instructions with how to minimize the harm they will incur doing so is not the message we're trying to send here.