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  • PD Moderators: Esperighanto | JackARoe |

Is 25C-NBOMe safer than 25i?

As he said atm there aren't studies that could prove one is safer than the other, the response from what i've read and from what i've heard from friends it's varied and personal.
I think that most deaths/incidents induced from 25I rather than the others are just caused from the popularity and idiots selling it as LSD or safer compounds.
In my personal experience 25B is the one that gave less vasocontriction and muscle tension but this doesn't necessarily means that is the safest one.
I know many people that didn't have any problem also with 25C while on me it produced very bad physical effects even at 'normal' dosages.
Also 25D gave me no problems but i've heard some people saying it was very bad as a severe vasoconstrictor.
About DOC i didn't find it to be as problematic as some Nbomes, i've never passed the 5mg range and with my dosages i didn't feel much vasocontriction, tremors or cold feelings, it wasn't unpleasant on the body, well except once when i was really drunk before taking it.
 
I've merged your thread with a similar question which I think you'll find very relevant.

In short they all carry a similar risk so if you don't think you can use one safely then it's better not to use any.

Most other drugs are safer if only because of their easier handing and measuring.
 
Someone wanna explain vasoconstriction in English? Is it something to worry about in low to moderate doses? Say 500-1500ug?
Someone advised taking certain supplements beforehand to prevent vasoconstriction, how effective are these? Anyone know if its safe to combine with low doses of opiates?
 
Vasoconstriction is a result of drugs affecting adrenalin receptors in the body and causing blood vessels to constrict. It can cause cold extremities and a blue appearance to prone areas like the lips and knees.

In very severe cases it causes oxygen deprivation in which leas to tissue death and requires amputation.

Most people seem to confuse vasoconstriction with muscular tension, "body load" and general physical discomfort, and at moderate doses it is not an issue for most.
 
Vasoconstriction is a result of drugs affecting adrenalin receptors in the body and causing blood vessels to constrict. It can cause cold extremities and a blue appearance to prone areas like the lips and knees.

In very severe cases it causes oxygen deprivation in which leas to tissue death and requires amputation.

Most people seem to confuse vasoconstriction with muscular tension, "body load" and general physical discomfort, and at moderate doses it is not an issue for most.

Ah, I see. Explains the trips on Erowid saying they got chills with higher doses and tremoring from the chills.
I'm getting 900ug tabs so I won't be going beyond two hits at a time.

Whats the half life of these drugs?
I'm getting 2C-I-NBOMe tomorrow, and 25C-NBOMe later on in the week. No intention of mixing them, but wondering what period of time I should wait in between use.
 
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NBOMes build tolerance quickly and keep it for a while. Even after two weeks there is still some tolerance. I would avoid building tolerance as it's a good indicator that you're using a bit too often.

1800ug is rather a lot for 25I and is a whopping dose for 25C. Please take care. The half-lives are unknown. There is only about a year's anecdotal reports of use in humans, actual research outside of the original brain imaging studies is non-existent.
 
there both dangerous and stupid. jus get real L n if ya cant, get mush for crying out loud. iv had a couple friends take RC psychs and have too many adverse effects n some still have problems from the shit.
 
All drugs are dangerous but none possess the characteristics required to be intelligent or stupid.

Certainly the risks of bomamines appear to be higher but it is clear from the many positive reports that they can be used safely and that's why we're here. Telling people "this drug is (rubbish/dangerous/smells of fish) take something else" contributes nothing useful and dilutes the information available for those intent on trying them.

We are here to reduce harm, not preach abstinence. Drug users, of all the demographics, should know by now that abstinence-based education is not effective.
 
there both dangerous and stupid. jus get real L n if ya cant, get mush for crying out loud. iv had a couple friends take RC psychs and have too many adverse effects n some still have problems from the shit.

What a silly thing to say. Has it maybe occurred to you that people don't take NBOMe's because they want to simulate LSD but because they want to experience it's unique effects?

I'm starting to get really pissed with this attitude that acid is somehow superior to other psychedelics. I have had a couple of LSD blotters in my freezer for ages and haven't taken them. Why? Because I prefer NBOMe's.
 
To answer the op's question, absolutely not. I took 3.5mg of 25i and had one of the most profound trips of my life, while 2.4mg of 25c resulted in me waking up in the ICU with a breathing tube and a catheter.
 
Well, if you account for the potency of the two compounds, you took a higher dose of 25c than you did 25i
 
And your point? Neither chemical is safe, perhaps I should have made that more clear in my original post.
 
And your point? Neither chemical is safe, perhaps I should have made that more clear in my original post.
I think I speak for most near everyone when I say not true at all. Both are safe, but only when their boundaries aren't pushed to the point of hospitalization via direct ignorance of the dose.
Like others have said so many times, these drugs are literally so new that there is only a couple years(at best) of in vivo human anecdotsl reports of the effects of NBOMe's. Your report is just as bit important as the rest, I just hope you were taught a valuable lesson the day after 25C.
 
^ I tend to agree. But NBOMe's aren't safe of course. Hospitalisation or even death can occur. They have approximately the therapeutic range of paracetamol (tylenol). Take 5 or 10 times a sensible dose and risk serious damage.

It's just that unlike paracetamol, there's no commonly accepted reference to consult when deciding on a dose for NBOMe's. And of course, that's what we are trying to do here.
 
Expansion, these chemicals are absolutely not safe. That is a simple fact. LSD is safe. Marijuana is safe. Even aspirin is safe. NBOMes are NOT safe. Granted you probably won't die/end up in the hospital if you are responsible, but is that really how we are defining safe now?
 
Yet, it is estimated that somewhere between several hundred to a thousand people die from aspirin poisoning every year, many more than have died from NBOMes so far.

A useless comment. You're not taking into account the PROPORTION of people that took NBOME drugs compared to aspirin.

I've heard this faulty argument numerous times to defend NBOME drugs and sometimes RC's in general. Stop making us look bad.
 
A useless comment. You're not taking into account the PROPORTION of people that took NBOME drugs compared to aspirin.

I've heard this faulty argument numerous times to defend NBOME drugs and sometimes RC's in general. Stop making us look bad.

You misunderstand. I was not defending RCs. I was not saying that the NBOMEs are as safe as apririn. Clearly, the therapeutic index for NBOMEs is much lower than aspirin, and these compounds must be handled with great care. I was saying that no drug, with very few exceptions, is completely safe, so it is disingenuous to say things like aspirin is completely safe.
 
It's very simple. By no means can any phenethylamine be regarded as safe. They all call for responsible and informed use.
 
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