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Harm Reduction Intravenous Nicotine

Are you just bored, lacking real drugs, or are you honestly curious to experience IV nicotine? That idea has never even crossed my mind before.

I guess you'll see how it turns out then.

Those are actually interesting results.
 
Druidus said:
I know well what you meant.

I decide whether there is a point to this for me, and I see one, regardless if others don't. I decide which dangerous risks to avoid completely, and in this case, I think the dangers can be mitigated.

And I resent the idea that this is some sort of "dick-sizing" endeavor. I'm not doing this to look "cool" or "hardcore", I'm doing this for my own purposes that have nothing to do with that.
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well then since we appear to be on the same page intellectually, i apologize for the inference, sincerely. perhaps it was shortsighted of me to assume that there would be no earthly reason for someone to inject nicotine, in my head picturing someone injecting vodka or some other substance for which there is a widely accepted ROA merely for novelties sake. and, truly, all sarcasm aside it seems like you have your legitimate reasons for undertaking this endeavor and undoubtedly my own vices must seem pointless and asinine from many perspectives. i'm gonna have to leave this one alone and put it in the "different strokes for different folks" category. i hope you find what you're looking for.
 
the dose needs to be extremely low so you don't die. if you do 1 mg it will be like smoking a cigerette in 5 seconds. chances are you'll puke. if you must do this try 250 micrograms and push the plunger slow stopping halfway through to make sure your not dead.
 
down508 said:
the dose needs to be extremely low so you don't die. if you do 1 mg it will be like smoking a cigerette in 5 seconds. chances are you'll puke. if you must do this try 250 micrograms and push the plunger slow stopping halfway through to make sure your not dead.
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I thought it would need to be that low as well, yet in the abstract I quoted just above they mention their highest dose as 3mg/70kg. Seems high.
 
Considerations:
- Can you get pure nicotine?
- Is it soluble in water or another liquid that is safe for injection?
- How are you going to measure it with the degree of accuracy required?
- Injecting it is supposedly much more addictive than smoking it (there was a very old study done on that)
- Probability of unpleasant side effects is high
- I would not rely on the doses used in the study quoted above as being safe for you. There are so many factors to consider. I would start off with a ridiculously low dose if you are intent on doing this. Actually I would never ever inject nicotine. But you've already been told how risky this is.

I also think it's important to have someone on hand who can call emergency if it does go badly.

I'll see if I can do some more research on doses for you. But I'm also concerned about this thread aiding the illusion that any drug can be injected safely, especially outside of a medical setting. I worry people less equipped to do this in a safer (can't really say "safe" as there are always risks) manner will skim this thread and conclude it's a good/safe idea for them to inject some e-cigarette liquid or something.

EDIT: This study gave people doses of 100, 400, and 700 mcg (note that the participants were already smokers).
 
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I was wondering about this just yesterday, I think I either posted about it too on another topic or just wrote it and never posted... but anyway, personally I'm really intrigued about IV nicotine. I know what tobacco/nicotine does to my body when taken orally, sublingually, vaporized, smoked or transdermally. I'm especially interested in the differences of various tobacco vs. pure nicotine, I've made some interesting observations about absorption and effects that have taught me a lot about myself and pharmacology in general. For me doing a drug IS studying pharmacology... It doesn't feel weird to me at all that one would want to inject nicotine, although it is a bit strange topic on a harm reduction forum.

Let's just try to be as safe as possible as learn as much as possible okay? As for the dosage, someone said something along the lines "...that would be like smoking a whole cigarette in 5 seconds" I just have to comment that, I sometimes dry a whole cigarette completely, grind it to fine powder, mix it with cannabis and use a gravity bong to get it all in my lungs in under 5 seconds. It's really interesting how radically the effects are this way when compared to, say a nicotine patch that has over 20x more the amount of nicotine. Wasn't Shulgins tip on dosing for the first time (though he was working with virtually unknown substances at that point) "to take the least amount of powder that you think could possibly have an effect and then halve that" or something. Personally I think 50mcg sounds like a safe dose to start, but you never know.

And honestly, I believe people inject far more hazardous things than pure nicotine, it's unusual yes and we don't know much about what's going to happen, but can it honestly be as dangerous as, say, injecting impure methamphetamine? And this is only in the name of science anyway, right?
 
FnX said:
And honestly, I believe people inject far more hazardous things than pure nicotine, it's unusual yes and we don't know much about what's going to happen, but can it honestly be as dangerous as, say, injecting impure methamphetamine? And this is only in the name of science anyway, right?
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The main problems with injecting nicotine in comparison to other more commonly used drugs are that:
- it is extremely potent, meaning one would have to be able to measure it very accurately
- it has a more narrow window between desired effects and overdose than many drugs
- it is not commonly used so one doesn't have other peoples experiences to draw upon (this is not a factor to ignore)

Injecting an impure street drug is dangerous because you don't know what impurities or fillers are in it, but there are ways to reduce your likelihood of harm like processes and filtration to remove most of the impurities, and statistically it is not all that probable that it will contain some unknown super-potent impurity that is going to rapidly kill you. The danger of nicotine, however, is inherent to the drug itself. So it's difficult to really quantify the relative risk of injecting street drugs versus injecting nicotine.
 
Toucan said:
it just fails a risk/benefit analysis on all levels.
be rational please.

edit: I would like to point out that this isn't a sensible way to determine the subjective differences of pure nicotine vs tobacco as when using tobacco you don't IV it. It would be a better idea to get an e-cigarette and smoke the pure nicotine in that if you want to see the difference
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Couldn't agree more.
 
You really think the effects of IV nicotine are going to be different than freebasing it? The effects will be exactly the same, the effect response curve might look slightly different on the slopes... but i mean, i don't think anyone really cares.
 
Injecting nicotine? lmao Thats the funniest question i have ever heard. It has a low LD50 and is used as a pesticide...

Be careful, man!! I know what its like to wanna experiment with everything, but we are mortal creatures...it took me some time to realise this and i sometimes forget!! lol The human condition perhaps is playing games with you as it does many others?
 
Experience to expect at relatively high dose - seemingly acute visuals, burning/numbing sensation travelling trough body (try put a piece of tobacco on your tongue and imagine that feeling in your limbs)... Some euphoria, relaxation, increased heartbeat and alertness... etc... All the effects of a pack of smokes at once, without the phlegm... Shamans of the Americas use high dose tobacco in rituals and reach intense states of being. I once rolled 250 joints of a weed/additive free tobacco mix, and just from touching all that tobacco I got a psychedelic nicotine experience - drug absorbed through my skin...

So if you want an intense tobacco experience, for HR sake just make a foot bath full of water and tobacco :D But pull your feet out before its too late. Dose makes the poison.

EDIT: Note that lights vs reds, the latter doesn't necessary contain more nicotine, but the lights just have more holes in the filter to mix in more air. Hand rolling tobacco is relatively high in nicotine, pipe tobacco the highest. But seeing as you have pure nicotine I guess it doesn't matter... more for the lurkers wanting to make an extract and give it a go too... One small step for man, a giant leap for mankind - it may become a trend like e-cigs have, people injecting their daily nicotine doses to avoid carcinogens... LMFAO! Save the veins for the grail.
 
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What sort of scale do you have?
Nicotine is water, so if you have an accurate enough scale you could dissolve like 100mg in 1L of water, resulting in 100mcg/1ml.
I really don't think this is a good idea, but you're probably going to do it anyway, so at least practice some HR.
 
This reminds me of a timer I got curious and IVd caffeine.it was awful. I'm fairly sure this'd will be awful too, although if I had some I would probably do the same thing.. If I remember I will check back here to see how it went. Fwiw I am never interested in the opinions of those who don't IV when it comes to discussions about shooting anything, nothing personal but they simply don't get it.
 
^I have to agree with that post, and being an IV drug user/more specifically someone who has always been way too fiendish with IV stims, those studies did make me interested when the effects were confused with IV cocaine. However, the study didn't mention whether the people partaking in the experiment had ever injected cocaine before. If one has only sniffed powder cocaine, it would probably be easier to identify any drug that increased heart rate as 'cocaine'...it's just like how they've done studies with IV methylphenidate with coke users, and the results were similar, but what I really wanted to know (especially after I tried IV methylphenidate- which does not feel like iv cocaine FYI, the closest drug out there IMO, is MDPV and that doesn't really cause tinnitus/'a ringer' either) was if these coke users were intravenous coke users or crack smokers.

In the end I have to agree that the experiment seems to be too risky to try personally, but if this thread is to stay open I ask that people either post something useful, or nothing at all, and to the OP, I hope you don't try this.
 
edit:

Just saw your post zneg..about posting useful info. LOL,.

I really don't think it shoudl even stay open..there is no useful advice aside from don't do it.

Actually..my advice is, "experimenting" with drugs should not be taken literally. You don't want to literally experiment on your body with something potentially dangerous. Do you really want to be the 1st person to OD IVing nicotine? The 6 oclock news is going to end up talking about the epidemic of kids IVing cigarettes. When you buy that lucy you are going to be looked at as an crack addict lol,
 
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