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  • Trip Reports Moderator: Cheshire_Kat

Natural alkaloids, Euphoria body high, masturbation horniness and happinesss

aguythatlikessmoke

Bluelighter
Joined
May 16, 2012
Messages
667
Location
Central Eastern Europe
Kanna ( Sceletium Tortuosum)
I reckon this as amongst the top 3 psychoactive plants I think it is better than Kratom no lie.
My 3 best psychoactive plants/fungi
Marijuana, Magical mushrooms, Kanna Sceletium Tortuosum
0 hour I ate 2-3 grams of my beloved Kanna 'high potency' powder from a good vendor
within 15 minutes I notice waves of muscular relaxation and slight stimulation with Euphoria
at 30 minutes I notice that I feel horny I proceed to take a nice warm shower and then afterwards I masturbate my body has a high and I feel Euphoria and masturbation feels so good and my erection is so much stronger than Usual Seems Kanna increases Sexual desires because when I take this herb and I wander outside I notice the beauty of the female body so much more and I was watching porno for 15 minutes and jerking off hard wow this felt so good with Kanna in my body.
at 45 minutes after jerking off I am cooling off last night i took some amphetamines this herb is curbin the crash, I feel sedated all anxiety, negativity, depression is gone. I still feel Euphoria
at 1 hour I put on my music. Listen to a few songs.
at 1.30 hours I still feel a warmth in my heart and soul and a pleasant Euphoria, wow. Antidepressant effect is present. Kanna is an amazing herb, it gives you slight stimulation and horniness for me in the beginning at my higher dosages of 2-3 grams which proceeds to mental sedation and Euphoria and a calm, Empathogenic, Introspective where I feel happy to be alive and I can join existence.
at 2 hours effects subside
Anxiolytic effects last 5-8
Euphoria can last 2 hours
Following day can be felt with an afterglow sometimes reminiscent of mushrooms

My Kanna is from a good Vendor in Europe( i dont order it online buy it in Person) . It can help with so many things especially in the psychology spectrum Anger,Fear, Uncertainty,Insomnia, Mild to Moderate Depression, Anxiety, Stress, Tension.
Not only does it relax my mind it relives the tension within my body( muscles muscle relaxation) my soul. When taken orally, effects come up rapidly with some slight anxiousness, stimulation during the first 15 minutes. Stimulative effects 15-45 minutes they are reminiscent of caffeine but so much less anxiogenic. Then at the 30-45 minute mark Euphoria happens followed by Sedation but you feel happy. A 2-3 hour sedated feeling lasts Euphoria lasts 2 hours. It is mild to Moderate in intensity. Anxiolytic, Antidepressant effect lasts 5-8 hours though you feel at ease for the next 24 hours at least.
It increases the enjoyment of Music, it makes you feel good, I think it has a very good Therapeutic usage for the psychological spectrum), I do not think it has Physical addictive properties, Psychologically it can be addictive as it has good qualities though addiction to this substance psychologically wouldn't bring you any problems in fact it would bring you positivity joy and calmness in your life. It is a bit high on the price as it is a succulent herb from South Africa where indigenous tribes have been chewing and using it for hundreds of years. '
The active substance is Mesembrine a alkaloid found in it. It is a natural SRI Serotonin Reuptake inhibitor.
It is a potentiator of Cannabis and Alcohol for certain sometimes caffeine.
It amazingly potentiates alcohol and Cannabis you all have to try this combo its killer.
It is not addictive but you if you feel anxious or if you like to feel good you could start taking it often I have been using for 2 months daily. No negative at all.
It has reverse Tolerance to my amazement you can gain Euphoria many times from it, but it is a mild to Moderate Euphoria.
It has no negative effect on memory and other functions some studies indicate Nootropic effect.

I have been advocating the usage of Kanna( Sceletium Tortuosum) on Bluelight because i think it is great and very therapeutic. Also one more note at a certain dosage effects level off so even if you take a higher gram dosage you wont get more intoxicated . It is initially Stimulating and then later on Sedating similiar to other plant psychoactive it can lead to higher levels of consciousness too not hallicunogenic but introspective and investigating of ones life and paths.
It is Introspective and Empathogenic it also causes one to have great communication with other people. Increases Sociability and makes a person more open and friendly towards others. It gives you a buzz, it hits you and to me its better than Alprazolam,Xanax.
It makes you feel careless like xanax and less shy as well and it gives you this bright smile on your face, It has greater potency than Imipramine.

This is everything please People Post a reply I need input.
One More note Kanna Sceletium Tortuosum has greater potency than trycyclic antidepressant Imipramine.No withdrawal effects either.
Please input
 
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Not really. It is just your style of writing.

Good report. I am surprised that you get such a positive effect from kanna to talk of it as one of your choice drugs. I tried it once from a good source and found no noticeable effects.
 
Not really. It is just your style of writing.

Good report. I am surprised that you get such a positive effect from kanna to talk of it as one of your choice drugs. I tried it once from a good source and found no noticeable effects.

I am surprised about the Kanna " Sceletium Tort." as well and I always hate to hear that people didn't experience anything from it. I think it has to do something with your vendor and where your getting it from, I get mine in person. I don't order from the internet and I know mine came straight from South Africa( where some of indigenous tribes consume it, they actually take it throughout the whole day and stay intoxicated on it) its in powdered form but still has roots in it that are cut up the colour of my Kanna is light brown to dark brown mixed . I had gotten some strong Kratom from this Vendor, Maeng Da, it left me with a warmth and a strong Euphoria that I would say almost parallels amphetamine Euphoria, Almost deff more intense than Cannabis Euphoria and Kratom is awesome too cause it gets one social and talkative and reduces anxiety but the more you use Kratom negative effects tolerance and slight addiction built up.

I compared it to Kratom it is different than Kratom, Kratom by itself is most certainly more intense and lasts 2-3 hours for me Euphoria is there the first few times with Kratom then tapers as tolerance builts, When you built a Tolerance to kratom the effects decrease substantially with Kanna you can get Euphoria so many times. There is no tolerance whatsoever you can be taking it daily and you will always feel good on it and you can get Euphoric on it as well, if Tolerance does built up its very slight like if your usual dosage was 1 gram oral then after a while this dose leaves you feeling good with an antidepressant, anxiolysis but 2 grams will leave you intoxicated.
With Kanna what I loved was this Careless feeling, it is especially useful for anxiety. It feels like a weight lifts off your shoulders and you will smile and feel happier, like you will have a big smile on your face and people will think your high on pot or you took something its noticeable and sociability increases, you feel good, you don't feel moody its like an emotional uplift and Actually one of the people who I see often told me that he would be suprised to see me in a bad mood and I get it from other people as well that they don't see me in a bad mood too often , I've been taking Kanna for a while and its effective for mild to moderate depression and mild to moderate anxiety its even effective for individuals with no depression or anxiety cause it just keeps you on the positive side of life and you get over your problems on it easier and your able to keep your cool on it better . There is a slight Psychedelic effect like the Sun light will appear brighter and the colours and music and stuff gets slightly sharper, it is not hallucinogenic though. Mood lift is so evident. Muscle relaxation as well with stronger dosages like 2-3 grams oral first it starts off as a mild stimulation similar to caffeine without the side effects and then progresses to Mental sedation which will be with you or you will take a slight nap and sleep it off. Another thing that amazed me about Kanna was that I even had an AFTERGLOW like that what you notice with Magical mushrooms like the next day I would wake up and the world would assume a brighter view a more positive place to be in.
These afterglows they are experienced with your first few sessions of Kanna usage and so or after you've taken a break and then you use again. It shows that not only Psychedelic drugs leave you with a afterglow. It reminded of the magical mushrooms afterglow though not as strong.
Another interesting note with kanna is it is a potentiator of other drugs most strongly of Cannabis and Alcohol. It increases their positive effects.
It almost always has the effect of taking the anxiety out of certain drugs namely Amphetamine and Cannabis if you take kanna about 30 min to 1 hour before hitting a joint or taking amphetamines it will remove all the jitters, edginess, or paranoia and anxiety that some get sometimes on these substances.

Kanna tends to balance the Neurotransmitters in the Nervous system so I experienced that it enhanced my amphetamine highs as well .
Kanna can help you replenish Serotonin and Dopamine levels in your brain.
To make note though I can certainly agree that it acts on your Serotonin levels because it feels kind of like MDA and MDMA,Methylon,Butylone except it isn't so stimulating more so sedating and on a milder scale but it is a US patent forgot which number you can look it up, in this patent it indicates that Kanna active ingredient Mesembrine can have positive effects on Alcoholism, Drug addiction and Psychological spectrum disorders . It has Antidepressant effects stronger than the Tricyclic Antidepressant Imipramine according to the US patent as well and I can agree with that.

It is an interesting compound and not so well known either I just figured out about it this year there is not too much information on it out there either more research needs to be on it . And can you believe it? I have been using at times daily for weeks on in getting positive benefits such as Stress reduction, Euphoria, Anxiolysis,Antidepressant Tolerance to the effects don't seem to build or build only at a slight level . The strongest buzz lasts like 1-2 hours lets say 2 hours but it leaves me feeling good and calm for the rest of the day and into the next day as well. It is a PDE4 inhibitor too, and it seems to improve mental function too it also potentiates the effects of Coffee.
Also in a higher dosage of 2-3 grams oral it gives your body a high, a buzz and increases sexual drive like crazy I was like woo this is crazy. I think it can improve Sex the experience.
I have so much to write about Kanna it is consistent and a strong tolerance to its effects won't built up or Tolerance cause it works on Serotonin receptors. I consider it magical, it makes you feel good and it can give you mild to moderate Euphoria. I felt good on it.Introspective Empathetic state can be experienced as well. It is good in this sense because if your trying to find relief from Depression and Anxiety or other Psychological spectrum disorder you can use this substance it is subtle your intoxicated but it is not overwhelming like Cannabis or Shrooms can be for some. Shrooms help with Depression but sometimes the experience can be overwhelming, With Kanna it is always a subtle, gentle tide though strong Anxiolytic effects can be felt and you can feel very careless. It potentiates alcohol as well so one must be vary.
If I have more to write to you and others I will.
It is hard to find the proper vendor for Kanna and I don't seem to understand why one can't feel its effects. It has to do with the vendor I would recommend planting your own plant. :)
I am researching the bond between Humans and plants and I consider Psychoactive plants is the way for humans to go they always have so much less side effects and problems than the synthetic derivatives or the semisynthetic derivatives, you never experience a crash or anything sometimes you feel reborn the next day rather:)
As with shrooms. I consider these substances are a form of meditation and yes Kanna puts your mind in a meditative trance, it is essentially relaxing.
 
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I had gotten some strong Kratom from this Vendor, Maeng Da, it left me with a warmth and a strong Euphoria that I would say almost parallels amphetamine Euphoria, Almost deff more intense than Cannabis Euphoria and Kratom is awesome too cause it gets one social and talkative and reduces anxiety but the more you use Kratom negative effects tolerance and slight addiction built up.

This is a good example of how people react differently to chemicals. I have a good Kratom supplier (although I rarely use kratom), and even Maeng Da (likely the most potent strain) is hit-and-miss with myself, with even the strongest experiences being modest in their overall highs. I find the same with most sedating ethnobotanicals (kanna, lotus, kava, et cetera). This may be the result of having misused benzodiazapines when I was younger. On the opposite side of the spectrum, I am hypersensitive to all types of stimulants, even of the botanical nature (cacao, betel nut, ephedra, etc). Fortunately, I do not care for stimulants of any kind, whatsoever.
 
Kanna + Kratom is amazing. Throw kava in the mix and your set!

When I run out of my adderall , this trifecta keeps me flying high.
 
Very nice report, although I do beleive OP has a high sensitivity to enthobotanicals. I do think a big part of the problem and a good reason why they are still legal, is drastic differences in quality of product and sensitivity to those products.
 
Very nice report, although I do beleive OP has a high sensitivity to enthobotanicals. I do think a big part of the problem and a good reason why they are still legal, is drastic differences in quality of product and sensitivity to those products.

Yea with Kanna " Sceletium Tortousoum I noticed that smaller oral dosages of 0.5 grams to 1 gram give me a subtle buzz but larger dosages of 2-4 grams orally give me a great buzz with a strong buzz and intoxication and Euphoria that lasts 1-2 hours ( a moderate to strong effect) but with residual Anti-Depressant, Anxiolytic effects that last for 5-8 hours and Kanna also has an effect of keeping me a bit calmer for the rest of the day and easing sleep at night. It is an antidepressant. Also one more thing it reduces appetite you can control your body weight or loose weight if you need to whilst using this Herb. I feel that yea I do have a sensitivity to Kanna. Kratom is a different story though Tolerance builts up to it fast and the Euphoric qualities disappear (other opiod like effects calming,anxiolytic, Antidepressant effects pain reliever persist) and after 2 weeks of daily usage of Kratom I have to increase my dosages by a good amount or hit the stronger variant of Kratom Maeng Da to experience a strong effect.
With Kanna though it seems that Tolerance isn't an issue but yea I need 2 grams oral at least for a good buzz but for a medical effect/ Therapeutic effect though 1- 1.5 grams is good. I think the other factors/things that I have to deal with Kanna effects are concentration of the powder ( its not even throughout) because I buy mine in 25 gram packets and the concentration isn't even through out that means that one day I could take .5 grams of powder but its more concentrated and I could have a stronger effect than the next day if I where to take 1.5 grams that day because concentration varies in the 25 grams its not even throughout. YOu know? I can guarantee you one thing though if you take a tablespoon or two tablespoons of my Kanna that I have been buying you will experience Euphoria( Mild to Moderate) , Muscle relaxation, Mental Relaxation and its a sedative state too. Interesting thing to note though is that in the beginning phase of the Kanna experience right after you eat it the first 15-45 minutes if you take a good oral dosage you will sweat sometimes, and you will feel stimulated at first and your mind feels clear , Colours appear brighter, The world appears calmer, The sunlight for some reason appears a lot stronger than Usual I am uncertain why. And then this progress to mental Relaxation and a sedated state. Kanna is an amazing Potentiator of Marijuana I cannot emphasize this more to all of you, when your in the sedated phase of the Kanna experience lighting up a joint and it seems that the effects of Cannabis and Kanna both are intensified. Another thing That surpises me about this Succulent is that it Potentiates Alcohol so much no lie no freaking lie you will drink and get drunker and you will have a heavy body feeling. Its strange as to why Kanna even potentiates alcohol but it does. It makes drinking so much more pleasurable. But it is good for cravings as well.
One more note Kanna is mild and it can effect people differently, but I believe the effects should be there for more people why?
because if it had no effect then why would the indigenous tribes living in South Africa within the steep hills chew on Kanna for the whole day? The herbs use has been documented for 400 years . But it is a mild to moderate effect, nonetheless Ive taken higher dosages as well and I've wasted a bit of money on it as well but dont regret it at all.
I consider it a safer alternative to Kratom, Cannabis, and Alcohol and Cigarettes if your looking for a mild to moderate buzz.
Another thing it dissolves in water too so you can drop a tablespoon into a plastic bottle of water mix and shake and drink on that.
Its proven to be a more effective Antidepressant than Imipramine.
I have a lot to write because the herb its interesting and there is so much detail and information out there about Kratom, Cannabis and Kava but not too much info on Kanna.
Basically to sum up how Kanna effected me the first hour or two I notice a strong buzz and intoxication if I take a stronger dosage as mentioned or a stronger concentrate. Then I notice Anxiolysis, Antidepressant and Sedative effects last anywhere from 3-8 hours it also seems to surpress appetite its excellent for emotional eaters and it seems to have an effect of Stabilizing my emotions ( reduced negative emotions for the rest of the day) feeling okay with things) for the rest of the day though it doesn't seem to be like an antidepressant where you get all zombie mode.

Actually a Company in South Africa is trying to get a patent on this and it might come out as an Antidepressant Zembrin would be the name. It would have appetite supressant, Anxiolytic, Antidepressant type effect. I think this could be an alternative to Pharmaceuticals though.
Just my take on it, especially if they are able to get stronger concentrated versions of Kanna and mesembrine out.

I have a soft spot in my heart for this enthobotanical and I will continue to enjoy my Kanna. It seems that Humans are brains are wired and that the 4th drive of changing our mental state exists in all of us. :)
 
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This is a good example of how people react differently to chemicals. I have a good Kratom supplier (although I rarely use kratom), and even Maeng Da (likely the most potent strain) is hit-and-miss with myself, with even the strongest experiences being modest in their overall highs. I find the same with most sedating ethnobotanicals (kanna, lotus, kava, et cetera).

I rarely dig into the world of ethnobotanicals.
I've been really wanting to see what chewing khat leaves in like in comparison to caffeinated beverages (and the such). But am really discouraged because i'm just not sure if it is worth the effort.
 
I rarely dig into the world of ethnobotanicals.
I've been really wanting to see what chewing khat leaves in like in comparison to caffeinated beverages (and the such). But am really discouraged because i'm just not sure if it is worth the effort.

With the proper vendor and proper extraction techniques people have gotten a stronger Amphetamine like high on Khat then on Street Amphetamine or Adderall. Khat has effects they are strong go on Erowid and read up reports and Kratom is never hit and miss for me it always effects me sometimes a bit stronger sometimes weaker but its never hit and miss the high is shorter though 1.30 hours to 4 hours. I have had unbelievable Sedation on Bali Kratom and strong nodding, Sedativ, Euphoric and a bad nausea too. ;) Kanna I wrote a lot about it but I truly believe that it has benefits. Why would so many people in Africa Chew on Khat and Kanna if it had no effects????
I think it has to do with your vendor because if you get these plants in powder form with a strong alkaloid concentration effects occur. I even consider Kanna to be somewhat Magical on par with Cannabis and Shrooms. It lets me connect to the Universe, I have felt feelings where a barrier breaks between me and the world when I take Kanna. When you chew or swallow Kanna Sociability increases and Friendship and bonds increase as well, Peace and Tranquility increase. Your souls is unbound by its chains. This is another way I can describe its effects. Ok its on the milder spectrum but it has effects and it is stronger than the Antidepressant Imipramine. Mushrooms and Kanna I compared the too because both act on Serotonin and I have felt an afterglow with Kanna as well where I would wake up the next day and it would leave me with an afterglow type of effect where i would be more happier than usual more positive and in a better mood.
 
Dude I need this. Do you have any links to research on metabolites or the mechanism of action of it?
 
I agree with the OP, Kanna has totally changed things up for me. When I run out of adderall, I have been taking kanna , blue lotus, Meang Da Kratom, and kava extract.... but Kanna is the most important ingredient. It works just like he says... Kicks in with a strong adderall-type relaxed stimulation, then leaves you with a plesant relaxed come-down (if you can even call it that!) ...

its also fairly cheap, and you get way more bang for your buck than kratom. running out of adderall doesn't suck anymore.
 
How is the combo of Kanna and Kratom? My vendor sells both so I was thinking bout ordering em together next time... Anyone got info? And I also read in another thread it has ssri properties? How strong of a reuptake inhib is it? And one last question, which strain of Kratom did you find more pleasant in combo. Plz say red Bali or like red Sumatra. I love those....
 
How is the combo of Kanna and Kratom? My vendor sells both so I was thinking bout ordering em together next time... Anyone got info? And I also read in another thread it has ssri properties? How strong of a reuptake inhib is it? And one last question, which strain of Kratom did you find more pleasant in combo. Plz say red Bali or like red Sumatra. I love those....

Yes indeed Kanna has SRI not SSRI properties it a serotonin reuptake inhibitor not selective though more potent at Antidepressant effects than the original tricylcic antidepressant Imipramine.
Some more details
Benefits of Kanna (Sceletium tortuosum) include :

uplifts the mood,

gives you energy,

decreases anxiety, stress and tension.

It can also help with post-traumatic stress disorder, social phobia, and irritability.

Sceletium tortuosum has been used by hunter-gatherers and shepherds as a mood-enhancing substance for millennia, and is far more effective and rapidly acting than the well-known European plant Hypericum (St Johns Wort).

The mood-elevating action of sceletium is caused by a number of alkaloids including mesembrine, mesembrenol and tortuosamine which interact with the brain's dopamine and serotonin receptors.

Sceletium tortuosum is a small groundcover plant native to Southern Africa. For hundreds of years the Hottentots of Southern Africa used Sceletium tortuosum as a mood enhancer, relaxant and empathogen. (It is also known as Kanna or Kougoed.)

Historically, Sceletium tortuosum was eaten or chewed, or used as a snuff producing euphoria and alertness which gently fades into relaxation. If chewed in sufficient quantity Sceletium has a mild anesthetic effect in the mouth, much like kava. A tea made from Sceletium is sometimes used to wean alcoholics off alcohol.

Although the plant has been used for thousands of years in Africa, it is only now being sought by the West for its remarkable capacities to uplift the mood, increase energy levels and concentration spans. Sceletium is also being used as a natural anti-depressant that is safer than the pharmaceutical alternatives.

Kanna (sceletium) is used to rebalance the brain and nervous system and thereby relieve symptoms of depression. This has been proven to be extremely effective and safe.

Contra-indications :
Doctors recommend that it not be taken with other sedatives, anti-depressants, and heart medication. Whether or not it can be safely taken by pregnant women has not yet been scientifically confirmed but no cases involving any negative effects have been reported.

One more thing I wanted to note is that Kanna has very very interesting Synergist properties:
Compounds I have noted this with
Cannabis
Alcohol
Amphetamine
Coffee

with Cannabis, Marihuana it has a special synergy. What I felt I took 2-3 grams of Sceletium Tort. Orally. Waited then I started smoking on my joint took a few hits not too many. It increases the body high, decreases any associated paranoia, anxiety or negative emotions whilst on weed, It increases the feeling of stoned and you feel even more sedated heavy and more calmed down type of marihuana. Appreciation of Music is increased dramatically. Appetite is surpressed instead of increased due to Sceletium Tortuosum appetite supression effect. Increases feelings of connection and feelings of peace, tranquility even further whilst stoned. Allows for introspection as well and a positive mental shift of thoughts. But it can also cause one to get a very strong body high with even stronger sedation when combined with Cannabis. This Combo is especially good for those who tend to get paranoia or anxiety whilst smoking marijuana.

with Alcohol increases the effects of alcohol inhibition or social anxiety decreasing effects dramatically so no social anxiety is present whatsoever. Can you make you a bit more reckless whilst on Alcohol. Decreases your memory of the night even further. Inhibits you. Everybody is your friend. Even increases the body of Kanna the alcohol and leaves you feeling good, social and happy. Basically increases the effects of Alcohol you get drunker but a good drunk.

Coffee- increases the effects of Caffeine. Your mind feels clearer whilst drinking coffee. You have greater memory, concentration and other cognitive functions. you feel more stimulated yet less jittery.

Amphetamine- similiar to caffeine when Amphetamine and Kanna mix. Anxiety or Paranoia of Amphetamines decrease whilst at the same the Talkativity, Euphoria and positive effects increase.

This are my synergies. With kratom it seems that the Kratom overpowers Kanna. And one more note Kratom doesn't really have synergic effect only supression of other highs to me at least or it does have synergy with Amphetamine because it could calm you down .. Whilst Kanna 100 percent certain has good synergies with the above compounds.
The mechanism of action of Kanna especially Synergy beats me. I have no idea how it synergies with these compounds and the neurochemistry of synergy is unknown to me and many of the synergy aspects.
The Neuropharmacology of the other effects can be atributed to its action on Serotonin where it acts as Serotonin Reuptake inhibitor.
Dopamine where it can cause release of small to moderate amounts of Dopamine.
It also acts on Phosphoestirase inhibitor or PDE4 as stated online Compounds with these type of effects are known to be potent anti-depressant and anti-inflammatory agents. Perhaps it is Neuroprotective as well.
Yes Kanna also causes muscle relaxation and a stimulated calm feeling where your stimulated, emphaogenic and euphoric but not jittery as with other substances aka MDMA.
It is similiar to MDMA except more sedating and a bit milder.Less side effects.

Oh one more note Kanna is a stronger serotonin uptake inhibitor than Imipramine tricyclic antidepressant.
 
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I think Kanna and Kratom have a great synergy. Kanna will blend with almost any psychoactive substance.,... especially if its an herbal psychoactive.
 
The relationship between Man and Psychoactive herbs, plants and alkaloids terpenoids( Cannabis) has been going on since the existence of time. These plants are our counterparts they have a place in our hearts souls and beings and we can reep their benefits and their beauty.
 
More details in regards to Kanna , Sceletium Tortousuom some written reports by indviduals who use the substance.

Empathogenic Effects of Sceletium tortuosum
by Groot van derGros
The family Mesembryanthemaceae contains many pharmacologically active species. One of the most utilized by native peoples in South Africa was the genus Sceletium, for which whole tribes would travel hundreds of miles to pick a years supply. The plants of the Sceletium genus were utilized as an intoxicant; however much of the information available has been spotty and contradictory.

In an effort to clarify the role and usage of Sceletium in it's historical context a search was done on Medline which yielded the following information, derived from a report in the Journal of Ethnopharmacology (#50 1996 pgs 119-30)

As early as 1662 it is reported that a man named van Riebeeck bartered with the local inhabitants for sheep and Sceletium, which was very plentiful and considered the "…greatest clearer of spirits, and the noblest Restorative in the world…" In 1685 is was recorded by the second colonial governor of the Dutch Cape Colony, van der Stel, of the natives "…They chew mostly a certain plant which they call Canna…They use it as the Indians use betel or areca, and are of a very cheerful nature…it is held by them in great esteem as the betel or areca with the Indians. They chew its stem as well as the roots, mostly all day, and become intoxicated with it, so that on account of this effect…one can expect some profit from its cultivation."

Thunberg, during his 1773 expedition reported: "…The Hottentots come far and near to fetch this shrub with the root, leaves and all, which they beat together, and afterwards twist them up like pig-tail tobacco; after which they let the mass ferment and keep it by them for chewing, especially when they are thirsty. If chewed immediately after fermentation, it intoxicates." Laidler in 1928 noted that it was "…chewed and retained in the mouth for a while, when their spirits would rise, eyes brighten and faces take on a jovial air, and they would commence to dance. But if indulged in to excess, it robbed them of their senses and they became intoxicated."



Although primarily chewed, there are reports of it being taken as a tea (Jacobsen 1960) and also as a snuff (Jacobson 1960). Thunberg wrote in his journal in 1794, in reference to the San peoples: "…These people chew 'Canna' (Mesembryanthemum) and afterwards smoke it." Paterson, one who traveled in the same region wrote in 1789: "…this is called the Channa land; and derives it's name from a species of mezembryanteimum (sic) which is called Channa by the natives, and is exceedingly esteemed among them. They make use of it both in chewing and in smoaking (sic); when mixed with Dacka (sic) is very intoxicating, and which appeared to be of that species of hemp which is used in the East Indies by the name of Bang."
There have been many additional reports from self-experimenters who used the traditionally prepared material orally and most of these found a marked anxiolytic effect. "One informant used approximately 5ml of powdered 'kougoed' (sceletium) orally before giving a lecture that he was anxious about. He reported feeling relaxed throughout the lecture, with no cognitive impairment…one user claimed she felt that 'kougoed' was a truth drug….some felt that there was a synergistic effect with alcohol, and with smoked 'dagga' (cannabis sativa)…the chewing of 'kougoed' was reported to greatly enhance the psychoactivity of an inferior grade of cannabis smoked shortly thereafter…some reported euphoria as well as a feeling of meditative tranquility. Several users felt that the relaxation induced by 'kougoed' enabled one to focus on inner thoughts and feelings, if one wished, or to concentrate on the beauty of nature. Some informants reported heightened sensation of skin to fine touch, as well as sexual arousal.." (M.T. Smith, N. Gericke, et al).

In light of the above, some Sceletium tortuosum herb, perpared in the manner of the Hottentots was procured from South Africa and the following experiments conducted:

Sceletium is here understood to mean the dried herb, powdered herb or the tincture of Sceletium tortuosum

The first experiment consisted of combining approx. 50mg. Of dried Sceletium tortuosum with another smoking herb, the one most preferred by the Hottentots. After smoking the herbs, it was immediately apparent that there was a strong effect similar to Cannabis at first but without the dulling of cannabis. Empathic feelings beyond normal were noted. There were no hallucinations per se, but there was a definite visual "softening" in the appearance of objects and a subtle glow to everything. Feelings of euphoria were noted and a strong desire to dance and sing. This was offset somewhat by a slight, easily correctable effect on one's balance. The balance deficit was slight and temporary. After two hours the effects were still quite noticable but had waned somewhat. At this time I went to bed and had a good, restful nights sleep.

The next experiment was the following morning when I ingested approx. 50mg of the powdered Sceletium tortuosum as snuff. The effects were unlike those of the previous evening; in fact, there did not seem to be much of an effect at all, just a slight uneasiness. After 1 ? hours, I again tried some of the Hottentot herb and was amazed at the difference it made. The full effects of the previous night returned, along with a stronger empathy than before. Joy and euphoria were the keywords of this session, and the effects lasted for over two hours when I became tired as it changed effects to sedation. This is an effect that has been noted throughout the history of this plant and led to the contradictory descriptions of its effects among the early explorers. I took a long nap and awoke feeling almost normal, just a little of the Sceletium in the background.

Later that afternoon I smoked some more with a friend, this time around 100 mg. The friend only smoked a small part of it, but stated that he felt calmer and had noticed that he was talking less loudly and in a more calm tone before he left. I finished the remainder, and became concerned over having used too much. Visual distortions were noted, similar to looking through a pane of wet glass; some things seemd in focus and others not. This was somewhat unpleasant, but did not last long enough to be of serious concern.

The euphoria and well being/empathy was stronger than before. There was also a slight feeling of minor discomfort, possibly balance related and tending towards a slight dizziness. At times there seemed to be a slight headache, but it never developed into one, and was soon gone.

Early in the same evening, I tried another round of the snuff, this time more than the first time. It was harder to get to the euphoria and joy this time, possibly because I was tired and trying to keep up with the friends I was visiting. The friends did not try any. After a short while, the pleasant effects wore off and I found myself unhappy with the situation and short tempered with the people. I left and came home, noticing on the way that my perceptions were altered enough that I had to pay special attention to driving, even though it was late at night an there were no cars on the freeway.

The next day: After trying to sleep for hours, I got up at around 1 am and combusted some cannabis pollen. This was a big mistake; I became more awake than ever and felt flu-like physical symptoms all night. I finally managed to fall asleep around 5 am but was up again by 6;30 am. After being up a while, the flu-like symptoms dissipated leaving me just tired. Now, and all day so far, I have felt the "call" of this substance. It is as cloying in it's seduction as cocaine, and keeps wafting in and out of my conciousness. The message is "It felt so good, and this doesn't. This just feels ordinary; what's wrong with feeling good? Try some more".

The problem, as I discovered yesterday, is that a little bit is nice; too much makes you feel nauseous for a short while and kind of dopey and out-of-it. That and the visual distortions.

The joy that a small dose brings is very much worth it. After the initial joy, in about 45 minutes to an hour or more, a kind of calm contentedness sets in. One is emotionally detached and can put up with all kinds of bothersome people without any stress. After a while, that wears off, though, and they become more bothersome than originally. Unless you take more. This reminds one of cocaine, again. And, again, with another dose, the slight unpleasant effects become more accented as well as the good ones until they can overshadow the good ones, and it is time to stop.

The visuals remind one somewhat of mushrooms, but things do not melt (at least for me, at low doses) they just get "soft" looking, like being slightly out of focus. The colors and textures are accented.

As far as being a potentiator of cannabis, there is no doubt that sceletium has this effect. Much more was gotten from much less when sceletium was added.

Overall, it is my opinion that the pleasant effects of this substance, when used in moderation far outweigh the negative ones. Furthermore, the effects on cannabis potentiation are marked.

This is the report. My personal opinion is that the effects are generally even throughout the population they do vary in individuals some may experience more positive effects such as me and some may experience more Negative.

Another thing that came to my mind was that perhaps the effects of Kanna could even depend on your mental state or mental states yes that is what came to my mind. Basically past few months as I was using Kanna I was also dealing with Moderate anxiety and maybe slight depression if I could even call it that. I consider myself a somewhat anxious individual and maybe that could be another factor why its effects are so pronounced in me because it reads Kanna elevates mood and decreases stresss, anxiety and tension. It can be used as an appetite supressant to aid in dieting and weight loss. So for Kanna to have its maximum effect on Psychological state or mind set maybe you have to be slightly anxious to begin with. Who could agree with this?
I agree that it potentiates weed and it makes weed so much less paranoid like.
Its also great for inducing sleep especially like last night I partied the whole even used some coke and then I took Kanna when I got home no crash, no comedown nothing just sleep and normality. Remarkable herb.
For petes sake all alkaloids are remarkable.
I don't know if its addictive but I kind of feel like the guy in this post. When I start to feel good with Kanna sometimes I have to feeling that I want to repeat the consumption a few times daily sometimes I chew Kanna with bubblegum and if its taking Sublingually Kanna is so Narcotic a somewhat stoned state and feeling of indifferency and maximally reduced anxiety along with a strong body high and heavy body feeling perhaps even pain relieving. Sublingually Kanna is very potent and the effects come on rapidly I recommend putting some powder on gum and chewing on that for like 20 minutes. Effects last about 1 hour Sublingually and it then leaves you in a slightly boosted mood state for the rest of the day. Oral is the best method with dosages of 2-4 grams. Strongest effects are 1-2 hours in and if you take a higher oral dosage Euphoria can be expected or if it is concentrated alkaloids The euphoria on Kanna is nice, you can also feel horny, Muscle relaxation in your whole body a relaxed body state.
I love Alkaloids in General.
 
a couple more notes to mention. I love the Euphoria associated with Kanna since Kanna is initially stimulating the Euphoria I get from it I associate it with Cocaine yes not Amphetamine but Cocaine type Euphoria but obviously to a lot smaller degree this is when I take high oral dosages of Kanna. Though i must admit that although Kanna is sedating later on in your intoxication initially it is somewhat stimulating it is pleasurable no doubt about that and I enjoy it a bit more than Kratom. Though I have used Kratom as well Bali Kratom,Maeng Da. And Kratom is some potent stuff but my tolerance builts up to the feel good effects of Kratom and the Euphoric effects of Kratom rapidly with Kanna seems so that Tolerance to the feel good or feel Euphoric effect never builds up off course a few times I feel Euphoric or better but essentially always I tend to feel good on Kanna. Kratom makes me feel calm, drowsy, a heavy body feeling, nodding, relaxed, anxiolytic sedativ it is pleasurable as well. Kanna does give you an effect where you kind of feel slightly out of it. But Kratom is more potent stronger effect especially initially than Kanna ( whilst it remains more consistant) especially initially today I went back to giving a crack at Kratom I love it too had a nice nodd and a dream like state and strong relaxation of body muscle soul and mind.
SO I consider Kanna and Kratom to be grant and yes the Euphoric feeling of Kanna is just mental to me though I have physical effects. Whilst the Euphoria on Kratom seems a combination of both a physical and mental Euphoria. Its an awesome substance Kratom in that it functions as an opiate. It is addictive according to sources my honest view though it is an individual thing or reaction. Kratom lately I ve been using it once every two three weeks and seems i dont crave it nor do i use it excessive infact to myself I consider marijuana more addictive.
The taste of kratom is far worse than kanna kanna seems to taste good and mix with gum and chew on.
I am glad that I even got introduced to Kanna and Kratom in 2012 I can see why many indigenous tribes and so forth consider plants, alkaloids and such compounds to be holy or divine. Heck I even consider Kratom and Kanna to be divine and great compounds I think by far that their benefits outweigh the negatives and that more people should be introduced to them.
One more note with Kanna I notice decent appetite suppression not on par with stimulants but most certainly good. I would recommend Kanna to anybody who wants to lose weight, who feels that they are overweight, who are overweight or who are obese. I can describe its appetite suppression as not craving food and not thinking about food although if you want to eat you could grab something and eat it. I have gone maybe 7-8 hours and up to 10 hours in a day without food whilst using Kanna. When Kanna is active you notice that you just don't feel hungry and you get your appetite supressed and you dont get think about food. Good supplement for weight loss.
 
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