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Cause of psychedelic effects when IVing megadoses of Ethylphenidate?

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hallucinogenic or not I rather gather that gaseous serotonin in the brain would not be a good thing!
 
Toucan said:
hallucinogenic or not I rather gather that gaseous serotonin in the brain would not be a good thing!
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Are you kidding, it is fucking great! Have you ever tried "computer duster"? that is pure gaseous serotonin. So, I think we've solved this here mystery. Massive doses of ethylphenidate injected causes the bends, but with serotonin instead of nitrogen. Case closed! (inhales deeply from the 4th can of duster of the morning, forgot my scuba tanks at home so I'm diving with duster today. And boy, I'm tripping balls!)
 
hallucinogenic or not I rather gather that gaseous serotonin in the brain would not be a good thing!
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Er....what? Gaseous serotonin is not a thing that can occur in the body...

I dunno. High doses of rapidly administered stimulants can be psychedelic in an odd way (in particular, with high enough doses, injected methamphetamine can manifest such), but usually, other effects overwhelm such.

ebola
 
amanitadine said:
Are you kidding, it is fucking great! Have you ever tried "computer duster"? that is pure gaseous serotonin. So, I think we've solved this here mystery. Massive doses of ethylphenidate injected causes the bends, but with serotonin instead of nitrogen. Case closed! (inhales deeply from the 4th can of duster of the morning, forgot my scuba tanks at home so I'm diving with duster today. And boy, I'm tripping balls!)
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Children should be seen and not heard.

Hallucinations from sleep deprivation are indeed caused by a change in the mechanism of serotonin metabolism. There is extensive research into this dating back to the 1950's.
 
fixing a hole said:
Hallucinations from sleep deprivation are indeed caused by a change in the mechanism of serotonin metabolism. There is extensive research into this dating back to the 1950's.
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What? In the 1950s, we simply did not have the tools to measure these types of effects. Please post some data to justify your claims or just stop.

ebola
 
fixingahole said:
Children should be seen and not heard.

Hallucinations from sleep deprivation are indeed caused by a change in the mechanism of serotonin metabolism. There is extensive research into this dating back to the 1950's.
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Oh rly? I guess that really dense and hard to decipher sarcasm went over your head. Serotonin and enteramine weren't even shown to be the same substance until like 1952, and we still thought it was primarily involved in vascular action. Provide some sources, because you started talking even more shit unfamiliar to me. There wasn't even the technology nor knowledge for such back then!

Edit- quoting from past page. Ham and Ebola said it better than I. As is their wont. Kudos.
 
Gerard A Kerkhof, Hans Van Dongen - Human Sleep and Cognition, Part 1, Volume 185: Basic Research (Progress in Brain Research)
Gerard A Kerkhof, Hans Van Dongen - Human Sleep and Cognition, Part II, Volume 190: Clinical and Applied Research (Progress in Brain Research)

Do some fucking reading!

amanitadine said:
Ham and Ebola said it better than I. As is their wont. Kudos.
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Lick, lick, lick! ;)
 
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It was quite obvious to anyone with a brain. It's not a 'silly' analogy because in the case of sleep deprivation - as in the case of 'the bends' - something that is normally non-toxic becomes toxic due to a change in the way that it is metabolized by the body. The books listed above and the references given therein are more than enough for anyone who is interested in reading about the scientific causes of hallucination due to sleep deprivation. It would be an oversight to miss the fact that most people are ignorant and aggressive fools who have nothing better to do with their lives than proclaim their ignorance over and over again. So kudos for that! I won't bother talking science too much on here. Petty name calling seems to be the way that the regulars like to keep it. Are you still running the blacklight forum Hammilton? Can you send me my password again please, I've lost it like a moron! I hope it's ok to mention blacklight on here. :p=D
 
Sorry fixing, a bad choice of words I didn't mean to patronise I was just making a joke before that's all :)
It's be best to try and keep a cool head when discussing these things though especially when suggesting new ideas or people will be very dismissive.
 
Man! Try and talk about 'science' around here and old timer blacklight drugs-kingpin calls me a 'moron', a moderator asks me to 'stop' ("a hole" - very subtle!), and an all-round arse-licker tells me that 'we' couldn't possibly have achieved what I've just spent hours reading about. I don't give a shit if people are dismissive! I've obviously spent too long studying and not nearly enough time around ignorant kids.
 
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and now this thread comes to a close. I can't see much more productive discussion coming from IV stimulant megadoses anyway.

If someone wants to post some whitepapers on the role of serotonin in sleep deprivation in a new thread that'd be cool
 
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