I get decent effects from it without any special mixtures, doses above 25 mgs. But I don't use it cause I don't feel it is safe for recreational use.
It is not safe for recreational use. I seem to recall reading somewhere that it is potentially neurotoxic.
That said, when I was trying to quit using hydromorphone (or any opiate/opioid at all - I was an IV user), I did use it. It didn't help nearly as much as a really solid dose of poppy seed tea did, and, as well, when I used it for 3-4 days in a row, I got a marked diminishment of effects as repeated dosing went on. Tolerance rises rapidly, IME. If I had to pick another opiate that the high most resembles, I would choose methadone. It seems like a low dose of methadone, perhaps, with considerable sedation. Sleep length is extended, as well as the "deepness-feeling" of the sleep. You will be very groggy on it, at recreational dose level, it can be overpowering, lol. You will also be constipated for a few days from one use - that's a fact, folks.
The way I achieved rec. effects from loperamide was this: First, don't skimp, buy brand, it works better. Then, lacking an enzyme inhibitor, you must mega-dose the drug. I tried 90-120mg at a time, settling at 100 for a good optimum experience (however, take into account that I was a regular high dose IV user of hydromorphone, so your tolerance may vary). The 1mg they give you for medicinal effects is only enough to hit engenous opiate receptors that are located outside of the brain. Yes, it does not cross the BBB very well at all. But to some extent, it still does; to a useable extent.
When you take a dose like 100mg,
enough of the loperamide in your blood can cross the BBB to start actually producing psychotropic effects. The rest of your body will be swamped in the stuff, producing the strong physical side effects. But you WILL achieve rec. effects, even if they are minimal or not favoured particularly.
