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Opioids 5000mg yesterday, and 5000mg today of acetaminophen

L

LuckyandBlessed

Greenlighter
Joined
Nov 29, 2012
Messages
4
I have a pretty big tolerance for Lortab 7.5/500. I have been taking 3000mg a day for 2 months or so since I got in an accident. Dosage is 2 in morning, 2 at lunch, and 2 at dinner.

Yesterday, Itook 5000 mg over the course of the day. (4 in morning, 2 mid morning, 2 at lunch, and 2 at dinner) Didnt take any after 7pm. Today at 9am, I repeated yesterday.

I do not plan on taking anything tomorrow. I am currently feeling fine. No notifications of overdose. I was just reading tonight, and saw people freaking out about taking this much. I just have such a high tolerance, I didnt think this would be an issue.

insight?

thanks -ME
 
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Welcome to BL. Here, we don't allow the use of SWIM. Please read the BLUA and OD Guidelines as you agreed to upon creation of your account, and edit your post from SWIM to the correct I, me, myself, etc terminology.
 
DO NOT TAKE ANYMORE APAP!!

3000mg is the daily limit.

I would go to your dr and get get a liver check done by a blood test...I HIGHLY suggest this.

Also we do not use SWIM, please read the BLUA.
 
tricomb said:
Welcome to BL. Here, we don't allow the use of SWIM. Please read the BLUA and OD Guidelines as you agreed to upon creation of your account, and edit your post from SWIM to the correct I, me, myself, etc terminology.
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Ill do it right now, hang on
 
Tolerance doesn't have anything to do with how toxic acetaminophen is to the liver, just like how alcohol will still damage the liver whether you have a tolerance to it or not.

If you continue to take upwards of 3000mg of acetaminophen a day then you should do a cold water extraction on the pills. If you are going to exceed that amount then you definitely should do it, otherwise you are really risking liver damage.

Right now you can take some milk thistle since it can help prevent and limit the damage done to the liver by toxins (source).
 
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I plan on just taking it easy for the next few days, not taking any at all. I have been reading alot about the signs of an overdose, and I currently have none.

Tommyboy said:
Tolerance doesn't have anything to do with how toxic acetaminophen is to the liver, just like how alcohol will still damage the liver whether you have a tolerance to it or not.

If you continue to take upwards of 3000mg of acetaminophen a day then you should do a cold water extraction on the pills. If you are going to exceed that amount then you definitely should do it, otherwise you are really risking liver damage.
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I will do CWE when I start back taking them again. I plan on drinking alot of water tonight. Any other tips?
 
A lot of people don't show any signs of acetaminphen overdose in the first 24 hours. If you experience any sweating, nausea, vomiting, or become pale, seek medical attention immediately.
 
HaZeX said:
DO NOT TAKE ANYMORE APAP!!

3000mg is the daily limit.

I would go to your dr and get get a liver check done by a blood test...I HIGHLY suggest this.

Also we do not use SWIM, please read the BLUA.
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Sucks how you always get different imformation from different people...where the heck did you hear its 3000mg max a day, ive been hearing 4000 up until now..?
 
Tommyboy said:
A lot of people don't show any signs of acetaminphen overdose in the first 24 hours. If you experience any sweating, nausea, vomiting, or become pale, seek medical attention immediately.
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You want him to seek medical attention if he experiences nausea ? loool.
Come on now yes your trying to give him safe tips but there are 100s of things that can cause nausea lol....stop trying to scare the guy so much.....
 
EEhouseEE said:
Sucks how you always get different imformation from different people...where the heck did you hear its 3000mg max a day, ive been hearing 4000 up until now..?
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It used to be 4000. It is now 3000. -FDA ... not sure of the date that this took place though.

I will seek medical attention tomorrow if I feel weird at all. But based on my body being used to this drug, what are the chances of these past two days having a negative effect? I just dont see how 3 or 4 extra a day can make such a huge difference.
 
the liver is one of those organs that can repair itself if you let it. Your not going to feel pain in your liver, it just doesnt work like that. If you continue taking high doses of APAP your liver is going to develop liver disease and if you still continue your habits then it will be so scarred that it will be unable to recover. Stop now before you destroy your liver
 
EEhouseEE said:
You want him to seek medical attention if he experiences nausea ? loool.
Come on now yes your trying to give him safe tips but there are 100s of things that can cause nausea lol....stop trying to scare the guy so much.....
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It's not like the average person experiences nausea that often, so if they experience it within 24 hours of taking a dose of acetaminophen which is considered toxic then yes, they should seek medical attention. There are 100's of things that can cause a lot of the overdose symptoms, but if you just took the drug then there's a good chance that that's the culprit.
 
LuckyandBlessed said:
I plan on just taking it easy for the next few days, not taking any at all.
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Easier said than done. Have you tried abruptly discontinuing the hydrocodone before? If you've been taking it multiple times a day for months and developed a tolerance, you will likely experience withdrawal symptoms (from the opiate, hydrocodone. Acetomeniphen does not have any withdrawal syndrome as far as I know.)

Are you using more than you're prescribed due to pain, or just because you like the euphoria? Either way, consuming such large amounts of Tylenol is not healthy at all. I would definitely recomend the CWE like Tommyboy mentioned, or using a different pain med all together that doesn't include APAP or Ibuprofen (such as Morphine which is almost equipotent to hydrocodone when taken orally, so figuring out the right dosage would be easier. Morphine also comes in an extended release formula as well as an IR, which would offer effective pain management with less dosing).

If you do end up CT, you should take the next few days off from work/school.
 
Go to the doctor and tell him that you would rather have Norco 10/325s than what you have now because your liver will thank him.
 
Oxie's right - but I'd make a point of saying you want fewer Norcos, so you don't get 'drug seeker' stamped on your files. If you develop symptoms from recent overidulgence, then seek medical attention - but 5000mgs two days in a row, while bad for your liver, is a long way from the kind of doses likely to be fatal. I'd keep an eye on yourself and how you feel, but don't worry overmuch. And don't do it again.

Also, as I understand it, tolerance doesn't really develop to APAP, and certainly not to its toxic effects. I think there's a rarely-prescribed hydro/ibuprofen blend - maybe you could ask to switch to that for a while, both to save your liver some damage, and because daily APAP use can cause rebound headaches.

There are many things I miss about living in the US (now based in Europe): hydrocodone and draught root beer top the list. Hydrocodone is NEVER precribed here, and when I was fairly opiate-naive, two Vics with a low dose of Xanax and 50mgs sumatriptan were the only cocktail that would really control my migraines. Then, of course, I started CWE'ing Vics, and raising the Xanax dosage, and things went downhill pretty rapidly. They don't prescribe it over here, I think, because it's so short-acting and euphoric that it can be a quick path to opiate addiction. Though at a pinch, dihydrocodeine is quite similar, though without the buzzy, upbeat Vicodin feel - it always struck me as a combination between low-dose MDXX and an opiate.

If you can't get Norcos, have you tried potentiating with diphenhydramine or doxalymine succinate? Even with a substantial tolerance, two Norcos 90mins after a dose of diphen gave me a noticeable, if brief high, though of course it does make the experience more sedating.
 
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3 grams of APAP a day is not much, and an occasional dose of 5g /day won't hurt you. Just keep your daily intake at 4 grams or less, and you will be fine. Your liver won't explode at the 4 g/ day level ;)

But just in case, take a n-acetyl-cysteine (NAC) supplement every day, it's what they use intravenously for APAP poisoning, it helps the liver dealing with excess toxins. And it's a good antioxidant :)
 
Yeah, that is an outrageous amount of APAP. I'm with Tommyboy.. be on the look out for symptoms that come in the appropriate time span after taking your dose because it's quite dangerous. Better to be safe then sorry.. it could be nothing, but a lot of times the line between "i'm fine" and "i'm fucked" is pretty thin, meaning it doesn't take much to go from okay to very not okay.
 
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