- Joined
- Apr 4, 2006
- Messages
- 19,555
Sorry to hear you've been having such of a rough go of it
. Hugz 
A anti-histamine anti-nausea drug like dimenhydrinate could help the nausea and dizziness with valproate. It also doesn't carry the risk of EPS as it does not affect dopamine. Metoclopramide doesn't help my nausea at all in treating anything so sucks drug. Largactil aka good old Thorazine kills my nausea but carries about the same risk of causing movement disorders as Stemetil does so yeah not a good idea for you. Metoclopramide is actually one of the worst drugs out there for causing tardive dyskinesia and EPS. It causes tardive dyskinesia in about 20% of patients who take it longer then 3 months which is way too high odds for me to risk that. My doctor prescribed me 40mg's a day, told me to take it everyday and gave me a years worth of refills! That just shows how clueless doctors are and it's a damn good thing i knew better.
If the valproate doesn't work then i would highly suggest pushing to try lamotrigine. The worst thing about lamotrigine is that due to the risk of Stevens–Johnson syndrome you have to taper up the dose very slowly. It took about 3 months for it to fully kick in and get to 200mg's a day. That is when the mania really improved and the mixed states and rapid cycling stopped pretty much altogether. I had a mixed state earlier the summer but i don't think anything would have stopped that. Way too much stress
. However it started working on the depression side of things after i hit 50mg's a day and you may not need to get to 200mg's a day since lamotrigine is very variable in how it affects people. That is assuming it works for you as no 2 people are the same. You can take it with lithium and that is actually a pretty common combo to control bipolar 1 disorder. Maybe you could take something else along with it to help control your moods. I think you've tried zyprexa and seroquel haven't you? I found zyprexa to be the bomb in treating mania and mixed states. The zyprexa zydis would stop my worst mixed states dead in it's tracks 20 minutes after taking it although i sometimes needed to take 20mg's if i was really bad off.
I know the med merry go round is really frustrating and a pain in the ass but it will be worth it when you find the right meds believe me.
Anyway keep in touch and let us know how your doing okay. And you know you can message me anytime you want if your feeling fucked up or just want to talk. Best of luck to your cute little self


A anti-histamine anti-nausea drug like dimenhydrinate could help the nausea and dizziness with valproate. It also doesn't carry the risk of EPS as it does not affect dopamine. Metoclopramide doesn't help my nausea at all in treating anything so sucks drug. Largactil aka good old Thorazine kills my nausea but carries about the same risk of causing movement disorders as Stemetil does so yeah not a good idea for you. Metoclopramide is actually one of the worst drugs out there for causing tardive dyskinesia and EPS. It causes tardive dyskinesia in about 20% of patients who take it longer then 3 months which is way too high odds for me to risk that. My doctor prescribed me 40mg's a day, told me to take it everyday and gave me a years worth of refills! That just shows how clueless doctors are and it's a damn good thing i knew better.
If the valproate doesn't work then i would highly suggest pushing to try lamotrigine. The worst thing about lamotrigine is that due to the risk of Stevens–Johnson syndrome you have to taper up the dose very slowly. It took about 3 months for it to fully kick in and get to 200mg's a day. That is when the mania really improved and the mixed states and rapid cycling stopped pretty much altogether. I had a mixed state earlier the summer but i don't think anything would have stopped that. Way too much stress
. However it started working on the depression side of things after i hit 50mg's a day and you may not need to get to 200mg's a day since lamotrigine is very variable in how it affects people. That is assuming it works for you as no 2 people are the same. You can take it with lithium and that is actually a pretty common combo to control bipolar 1 disorder. Maybe you could take something else along with it to help control your moods. I think you've tried zyprexa and seroquel haven't you? I found zyprexa to be the bomb in treating mania and mixed states. The zyprexa zydis would stop my worst mixed states dead in it's tracks 20 minutes after taking it although i sometimes needed to take 20mg's if i was really bad off. I know the med merry go round is really frustrating and a pain in the ass but it will be worth it when you find the right meds believe me.
Anyway keep in touch and let us know how your doing okay. And you know you can message me anytime you want if your feeling fucked up or just want to talk. Best of luck to your cute little self

