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About Desmethylprodine (MPPP) neurotoxic analogs

M

mllx

Bluelighter
Joined
Nov 11, 2011
Messages
59
Hi everyone,

A few weeks ago I bought 1 gram of Desmethylprodine (MPPP). I sent a sample to get a GS/MS analysis.
The analysis found Desmethylprodine and another unidentified product, but this product isn't MPTP.

So my question is: are there another neurotoxic synthesis subproducts that act like MPTP? Or MPTP is the only that kills dopaminergic cells?

I know that normeperidine is neurotoxic, so probably MPPP have neurotoxic accumulative metabolites, but I only want to discard the formation of another MPP+-like compounds.

Thank you!
 
As far as I know only MPTP is the major toxin, but get a solid ID on what the "other compound" is - the tertiary alcohol could in theory rearrange under heated conditions to MPTP.
 
Got some too, it's analysed and no MPTP only one NON identified purity.

Can you smoke the MPPP? If you heat the MPPP / Desmethylprodine , will it form MPTP?

Regards! :)
 
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did you get the GC/MS data? and can you pls post it here? Maybe we can help you identifying it
 
i seriously doubt that MPTP will form just from heating the MPPP, it would require hydrolyzing the ester and having the resulting alcohol pop off, BUT you dont know what the other impurity is, which may form MPTP upon heating. why risk it? if theres a decent chance of getting parkinsons from getting high once, why not look for another opiod?

edit: never mind, DO NOT SMOKE MPPP
from wiki: "However, the intermediate tertiary alcohol is liable to dehydration in acidic conditions if the reaction temperature rises above 30°C"
 
I guess that the statment from Wikipedia refers only during formation on MPPP, but anyway I wouldn't risk, I won't smoke MPPP.

I ask for the spectra of the unknown compound, if I get it I will post it here.
 
Well formation of MPTP is more a problem during the synthesis not from the product. So if there is none present in your product you wont be able to create it after wards.
 
Torabora said:
Well formation of MPTP is more a problem during the synthesis not from the product. So if there is none present in your product you wont be able to create it after wards.
Click to expand...

So if I smoke the compound no MPTP or other neurotoxic molecules that will cause permanent parkinsonism will form and affect me?

Regards! :)
 
I tried it this morning, I suspect that the unknown compount is just a strange diluent for vaporizing it easily (and extra $$$ for the vendor, of course).
Very stimulant and dopaminergic, I guess Demerol is something like that. Good analgesia also, of course.
 
hmmm mllx but stay safe and dont take it to often wait for some weeks and watch how you feel
 
Torabora said:
hmmm mllx but stay safe and dont take it to often wait for some weeks and watch how you feel
Click to expand...

Of course, even it isn't my kind of opiate, I don't like DRI-like drugs,and this is very dopaminegic and stimulating.
I've only tried it one time but at the moment I'm fine.
 
Hi!

Here I have the spectrum of the unknown substance. There's 2 graphics: first the Gas Chromatography of the sample (MPPP+unkown substance), and the second is the Mass Spectrum of the unknown substance.

Any chemist could help?

Thank you!

http://www.sendspace.com/file/xjphll
 
mllx, good day; hope all is well. I also have experience with Desmethylprodine, an excellent opioid. I do not find it stimulating(at all), but rather relaxing. After the rush typical of parenteral morphine, its exactly like morphine and other opioid drugs, and I often find myself nodding out and feeling very doped up. So IDK about this stimulation you speak of. I actually feel it's most similar to oxycodone, mg for mg & effect wise. Of all the opioid drugs ive used, I must say the 6-keto phenantherene opiates (hydrocodone, oxycodone, hydromorphone, oxymorphone) do share a unique similarity, despite them being different opiates in many ways. I think MPPP is most like the 6-ketos in terms of its effects. Are you sure its 1-methyl-4-phenyl-4-propionoxypiperidine and not 4'-Methyl-α-pyrrolidinopropiophenone? Just doesn't sound like MPPP your describing. -Be Well, stay safe **Test shots save lives.**
 
DILAUDID 8mg said:
mllx, good day; hope all is well. I also have experience with Desmethylprodine, an excellent opioid. I do not find it stimulating(at all), but rather relaxing. After the rush typical of parenteral morphine, its exactly like morphine and other opioid drugs, and I often find myself nodding out and feeling very doped up. So IDK about this stimulation you speak of. I actually feel it's most similar to oxycodone, mg for mg & effect wise. Of all the opioid drugs ive used, I must say the 6-keto phenantherene opiates (hydrocodone, oxycodone, hydromorphone, oxymorphone) do share a unique similarity, despite them being different opiates in many ways. I think MPPP is most like the 6-ketos in terms of its effects. Are you sure its 1-methyl-4-phenyl-4-propionoxypiperidine and not 4'-Methyl-α-pyrrolidinopropiophenone? Just doesn't sound like MPPP your describing. -Be Well, stay safe **Test shots save lives.**
Click to expand...

Yes, the main substance is 1-methyl-4-phenyl-4-propionoxypiperidine. Anyway, I only tried it one time, so it could be even anxiety from a first-time use.
 
Okay, good, so were talking about the same substance. This MPPP stuff is great! But due to the 1977 Maryland and 1982 California MPTP incidents, most chemists (and users) stay away from this opioid. I mean, "the case of the frozen addicts" is scary to think about. Also I take into account that This MPTP impurity happened twice, in two separate geographical areas, by two different chemists. However, when prepared and stored properly it is a safe, moderately potent opioid analgesic. Though we cannot discuss certain specifics, surely you have experience with other opioid drugs right? You know what to expect, right?? Of my "friends" that (ab)use opiates, and are opiate tolerant, 2 were convinced that is was genuine Heroin. One believed it to be MSO4 or a lower dose of Hydromorphone. All were surprised to find out that it was totally synthetic. I'm curious about your opinion of this chemical. Like, How was the rush, the high, and how long did you think the "legs" were? What side effects were there for you (nausea, itching, sedation, constipation, miosis, etc). If you'd like more specific's from me, please lemme know- I'd be happy to be of any assistance. We should share our information. take care
 
DILAUDID 8mg said:
Okay, good, so were talking about the same substance. This MPPP stuff is great! But due to the 1977 Maryland and 1982 California MPTP incidents, most chemists (and users) stay away from this opioid. I mean, "the case of the frozen addicts" is scary to think about. Also I take into account that This MPTP impurity happened twice, in two separate geographical areas, by two different chemists. However, when prepared and stored properly it is a safe, moderately potent opioid analgesic. Though we cannot discuss certain specifics, surely you have experience with other opioid drugs right? You know what to expect, right?? Of my "friends" that (ab)use opiates, and are opiate tolerant, 2 were convinced that is was genuine Heroin. One believed it to be MSO4 or a lower dose of Hydromorphone. All were surprised to find out that it was totally synthetic. I'm curious about your opinion of this chemical. Like, How was the rush, the high, and how long did you think the "legs" were? What side effects were there for you (nausea, itching, sedation, constipation, miosis, etc). If you'd like more specific's from me, please lemme know- I'd be happy to be of any assistance. We should share our information. take care
Click to expand...

Thank you for your help and sorry for the delayed answer!

The impurity in my MPPP is a dirty stimulant, I guess the vendor put it to prevent overdoses.
With a CWE extraction the efects are now more clearer: no more heart racing.
I only have experience with kratom, opium, AH-7921, tramadol and buprenorphine.
I tried yesterday my purified MPPP snorting it, is very euphoric but respiratory depression seems to come faster than other opiates . I snorted it.
Im gonna stay away from it untill I get pure MPPP.
 
How do you know it is adulterated with a "dirty stimulant" and that a "cwe extraction" removed it? *scratches head*
 
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