-
OD Moderators: Keif’ Richards | Tryptamino
Opioids subutex and morfine
- Thread starter Yomaukkis
- Start date
Znegative
Bluelight Crew
Depends.
I'm guessing you mean 2 mg (milligrams) of subutex rather than mL (milliliter)?
If you are Dependant on morphine, than taking the subutex on top of it, without waiting a good 24 hours is a bad idea, as it will cause precipitated withdrawal (subutex, or buprenorphine-the active ingredient, is a partial agonist opioid which can act like an antagonist by causing precipitated withdrawals if taken before withdrawals from a full agonist occur). However, if you take the morphine after 2mg of subutex, you will still most likely feel the morphine, though it depends on dosage and ROA (route of administration). For instance, I doubt that taking 10mg of oral morphine will have much effect on top of the buprenorphine due to morphines low oral absorption. But the same dose taken intravenously would most likely produce effects (not that I'm suggesting you shoot up morphine).
If you are naive to opioids/opiates in general, I would be careful with both of these drugs as they are rather potent. Especially with the morphine as you don't know how much you even have. Buprenorphine is also incredibly strong, and many people make the mistake of taking large dosages because they think it's not a "real opiate" due to the fact that it's only a partial agonist. If you have little to no tolerance, I wouldn't take more than .25mg of bupe at a time, and make sure to wait at least an hour for it to kick in before deciding to up your dose.
I'm guessing you mean 2 mg (milligrams) of subutex rather than mL (milliliter)?
If you are Dependant on morphine, than taking the subutex on top of it, without waiting a good 24 hours is a bad idea, as it will cause precipitated withdrawal (subutex, or buprenorphine-the active ingredient, is a partial agonist opioid which can act like an antagonist by causing precipitated withdrawals if taken before withdrawals from a full agonist occur). However, if you take the morphine after 2mg of subutex, you will still most likely feel the morphine, though it depends on dosage and ROA (route of administration). For instance, I doubt that taking 10mg of oral morphine will have much effect on top of the buprenorphine due to morphines low oral absorption. But the same dose taken intravenously would most likely produce effects (not that I'm suggesting you shoot up morphine).
If you are naive to opioids/opiates in general, I would be careful with both of these drugs as they are rather potent. Especially with the morphine as you don't know how much you even have. Buprenorphine is also incredibly strong, and many people make the mistake of taking large dosages because they think it's not a "real opiate" due to the fact that it's only a partial agonist. If you have little to no tolerance, I wouldn't take more than .25mg of bupe at a time, and make sure to wait at least an hour for it to kick in before deciding to up your dose.
tricomb
Bluelight Crew
Until we know more about the background as ZNeg pointed out, I'm going to say, no, it's not a good idea to use the two together, and it's never safe to consume an "unknown amount of morphine".
morphonorconic
Bluelighter
Is the morphine a liquid formulation? If it is in pill form, do an ID and figure out what you have, otherwise be extremely cautious. And I'm also going to assume that you mean 2 milligrams of subutex, but we'd still need to know what your tolerance is like before making any recommendations.
Buprenorphine can be used concommitantly with full agonists like morphine, but the amount of bupe must not be too much or it will outcompete and saturate the receptors, as its binding affinity is much greater than that of morphine. It's best to stick to doses of 1mg or less when trying to acheive a synergistic effect with another [full agonist] opioid. To second what Znegative said, don't assume that because bupe is a partial agonist that it is safer to combine with another opioid/use recreationally. It is extremely potent, and if you aren't tolerant in general, you definitely shouldn't take 2mg, and should probably not take more than 0.25-0.5mg. Whatever you do, be smart and be safe.
Buprenorphine can be used concommitantly with full agonists like morphine, but the amount of bupe must not be too much or it will outcompete and saturate the receptors, as its binding affinity is much greater than that of morphine. It's best to stick to doses of 1mg or less when trying to acheive a synergistic effect with another [full agonist] opioid. To second what Znegative said, don't assume that because bupe is a partial agonist that it is safer to combine with another opioid/use recreationally. It is extremely potent, and if you aren't tolerant in general, you definitely shouldn't take 2mg, and should probably not take more than 0.25-0.5mg. Whatever you do, be smart and be safe.
ro0ga
Bluelighter
^ Yeah that pretty much sums it up.
[ignore]
As a side note, one of my pet peeves is when people spell morphine "morfine", amphetamine "amfetamine" etc. I don't know why, it just irks the hell out of me.
[/ignore]
[ignore]
As a side note, one of my pet peeves is when people spell morphine "morfine", amphetamine "amfetamine" etc. I don't know why, it just irks the hell out of me.
[/ignore]
mrflowers00
Ex-Bluelighter
bupe is not very recreational i'd stick to just morphine even though i dislike morphine
morfine is a common spelling in other languages, which is where the confusion probably comes from.
tricomb
Bluelight Crew
Considering I have no idea what "indaglin" is, I'm going to say it's a bad idea.
It's a good idea to use generic names so that we know what you're talking about, as these are international boards.
Where Wolf?
Bluelighter
Ethylmorphine isn't morphine proper - it's a weaker derivative, that creates a fairly massive histamine release (itchiness, other allergic symptoms) with very little recreational value. As Indaglin also contains a (presumably higher) dose of Indometacin, an NSAID (like Ibuprofenor APAP), this really doesn't seem like a good drug to abuse, least of all mixed with subutex. Take a look here:
http://en.wikipedia.org/wiki/Indometacin#Adverse_effects
Sounds a lot nastier, potentially, than naproxen or Ibuprofen. I'd suggest at least leaving the Indalgin for another time, if not flushing it.
http://en.wikipedia.org/wiki/Indometacin#Adverse_effects
Sounds a lot nastier, potentially, than naproxen or Ibuprofen. I'd suggest at least leaving the Indalgin for another time, if not flushing it.
sekio
Bluelight Crew
Mixing suboxone and other opioids is not a good idea, wait at least 24h between a high dose of suboxone (>2mg) and taking any other opioids for the best effects
n.
n.
for some strange reason this bothers me too.
on a sidenote completely unrelated to this thread, morphine was first isolated in 1804 by friedrich sertürner and named morphium, a name that's still prevalant in common german usage although morphin is the official name.
sekio
Bluelight Crew
As far as I know "amfetamine" was the British spelling (see also sulphur/sulfur... except strangely the other way around)