foolsgold
Bluelighter
just found this while looking around here the little bit of info there is on it
14-Methoxymetopon is an opiate analogue that is a derivative of metopon which has been substituted with amethoxy group at the 14-position. It is a highly potent analgesic drug that is around 500x stronger than morphinewhen administered systemically; however, when given spinally or supraspinally, it exhibits analgesic activity up to a million fold greater than morphine. It binds strongly to the μ-opioid receptor and activates it to a greater extent than most similar opioid chemicals. This produces an unusual pharmacological profile, and although 14-methoxymetopon acts as a potent μ-opioid full agonist in regards to some effects such as analgesia, a ceiling effect is seen on other effects such as constipation and respiratory depression.
just wondering if any one has tried this yet ?
14-Methoxymetopon is an opiate analogue that is a derivative of metopon which has been substituted with amethoxy group at the 14-position. It is a highly potent analgesic drug that is around 500x stronger than morphinewhen administered systemically; however, when given spinally or supraspinally, it exhibits analgesic activity up to a million fold greater than morphine. It binds strongly to the μ-opioid receptor and activates it to a greater extent than most similar opioid chemicals. This produces an unusual pharmacological profile, and although 14-methoxymetopon acts as a potent μ-opioid full agonist in regards to some effects such as analgesia, a ceiling effect is seen on other effects such as constipation and respiratory depression.
just wondering if any one has tried this yet ?