Yes, 2C's act as pretty caustic chemicals - the damage felt afterwards and the mucous/thick saliva abundantly produced in your mouth and stuff to dilute it after snorting plus the pain... yes I'd say all of that sums up that it is bad for your nose.
I have snorted 2C-B, 2C-C and 2C-D but would never snort the other less mild ones personally. I also think it is not worth it with any of these compounds and that plugging is far superior because it provides all the advantages without the negatives. If that idea isn't something you can live with, I'd say hold the complaints and just use them all orally which is quite fine as a ROA.
Also note that it matters which salt you snort. 2C-B HCl is significantly worse than the HBr due to water solubility.
im pre sure snorting anything causes some sort of damage...... wtf.....
The term significant would be important here... and for example snorting mannitol (a sweetener that does pretty much nothing in your nose) that serves as a carrier for a superpotent psychedelic, that cocktail would cause very minimal or better said 'insignificant' damage to the lining of the nose that should be repaired by the body quickly.
Things like mannitol are often snorted because they are present as cuts in street drugs such as speed or coke but it can be present in virtually every white powder, especially if not in crystalline form. But don't fool yourself, even crystalline compounds can be recrystallized with xylitol or if that is hard to do, melted mixed and solidified. Almost seems like a crystal. < true story.
So my point is: there are inert compounds, inert meaning: they do not react - they don't really do anything we should care about.
Conversely, frequent snorting of caustic phenethylamines in doses that seriously hurt and burn the mucous membrane, that would be significant because the damage can be
irreversible. That makes it damn significant.