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Have I changed/damaged my brain somehow?

D

done juan

Bluelighter
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May 6, 2011
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does it matter
ok first of all sorry if this comes across as being a really retarded thread.

on friday around midday i started on a binge. started with 4-mec, but got bored so added pentedrone into the mix. this binge went on until sunday evening non stop. i have no idea how much was consumed, reckless i know and not very clever in the means of hr. i also had a couple of bottles of JD too which again is not big and not clever. all in all i got about 2 hours sleep sunday evening. woke up in the am of monday with my alarm set for 6 am so i could gte my shit together to go and sign on at the jobcentre (previously been in work for a long time so kind of alien to me). From waking up and attempting to go to sleep time went soooo slowly and i was anxious as hell but definitely not going to risk any benzos with all that alcohol in my system. felt too shit to go to the jobcentre, needless to say i never got any sleep until the afternoon of monday which was probably half an hour to an hour at most.

at times when i was drifting off to sleep i would get an instant 'nightmare' which would shit me up, really bizarre stuff like being sprayed with water. anyway monday night dropped a benzo and got about 9 hours sleep.

this is where things change. since tuesday i have felt full of confidence, really chatty and basically not giving a shit, whereas before i was quite concious of my actions in general and consequences. i havent become reckless or anything but any kind of issues i may of had before have faded. is there some part of the brain that houses the emotions of fear? i have been thinking maybe its some kind of afterglow but it doesnt feel like that. i just feel more chilled about everything.

sorry if this is in the wrong forum, not too sure where to put it.
 
This is definitly not advanced drug discussion pm a mod and have em move it probably belongs in Other Drugs.


While its here ill answer your question. I think i have experienced the same thing coming off a good run a couple times before. to me it feels like i just got used to being fucked up and careless so it changed my mindset for a while. there is also the way drugs fuck with your brain chemistry but its not like it eats away your fear sensors or anything. This feeling usualy goes away within a week for me unfortunatly but take advantage and get shit done while you have it i guess.
 
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Sometimes when you do a lot of chemicals/ drugs it throws off your body chemistry. It may take a while for everything to go back to normal. Sometimes when you do this you permently alter your brain. It's really hard to tell.
 
From what I can tell (and I'm a pretty astute observer about any changes that any drug use causes in functioning) the brain is an extremely malleable organ. If you abuse RC stimulants regularly then I wouldn't be surprised if you have semi-permanent changes. If you only did this once or do it infrequently then I seriously doubt it. Taking a lot of drugs overall can have a negative cumulative effect also, though.

The best way you can tell how much damage has been done is to listen to your body for the strength and length of those after-effects. Since they don't appear negative beyond your sort of "hangover", I'd say the damage isn't to be that worried about. The brain usually does a good job of telling people when to stop. You just have to listen.
 
crimson wouldnt that lead to depression though?
ho im not complaining. if i had done something shrooms or even more extreme like iboga i could understand.
 
not necessarily on the depression part...serotonin is responsible for a lot more than your mood...
 
Yes, the brain dose have a specific area that handles fear, as it also does with emotions--generally speaking that is. But NO, I highly doubt you did any type of real damage to that area or your brain as a whole even...

IMO and IME, your just experiencing an afterglow / hangover type of phenomenon. Your particular symptoms sound exactly like the ones I get from a Benzo afterglow/hangover. Frequently, when I would take benzos, short or long acting ones, I would feel extremely confident, happy, and anxiety-free. It almost felt like I was actually on a benzo even though it had been a day since last taking any.

Stimulants on the other hand made me feel short tempered and angry the day after, so IDK about that element, but I've never taken an RC so I couldn't tell ya.

Most likely just a combo of lack of sleep and benzo after efffects are the cause of your symptoms, maybe also just ur body's response to a polydrug binge...
 
Zoeylynn said:
Sometimes when you do a lot of chemicals/ drugs it throws off your body chemistry. It may take a while for everything to go back to normal. Sometimes when you do this you permently alter your brain. It's really hard to tell.
Click to expand...

Right on the $$$

Yes people I know that neuroplasticity is real. Its a big reason why our brains rock extra hard: the brain has an amazing ability to adapt to deficiencies and surpluses of certain things, as well as recover from stuff. BUT, that still a change.

Analogy: rewiring a circuit to a roundabout way to fix a short is still a rewiring, even if the function ends up being the same different things are at work.

So: its possible you did. Its also possible its temporary. Only time (or a large battery of tests and evaluations by many, many, trained doctors) will tell.
 
my guess is the positives you notice will go away.
and maybe hopefully they wont?

i have been in similar situations, the experience can stay with you but generally you will feel like before once again
 
Yes you may have changed your brain chemistry

I'm always surprised how people are so willing to just combine lots of different psychedelic and other type drugs without any thought to how it affects their brain chemistry. As a rule of thumb, and this is by no means is absolute, anytime large amounts of a drug are requred to acheive the effect (ethanol and dextromethoraphan, etc.) the likelyhood of their being damage is almost always likely to increase (which is why toxicology is something all drug users should at least have a grasp of). But drugs like MPPP and 6-OH Dopamine do not need much to induce a parkinson-like syndrome so you should always be careful. I learned this with MDMA in the 80s when you could put it on your AMEX at certain bars before the (should be unconstitutional) Analogue Act was passed. The more you understand phase I biotransformaton, CYP450 enzymes and medicinal/toxicological chemistry, the more likely you can predict some of the oxidative damage that may occur from a drug, but things like Olsney's lesions and such are harder to figure (the neuroexcitatory damage patterns seem harder IMO to predict.

Now it is likely that I have done drugs and variations most of you have not, just because of my access to and unpublished modifications of many drugs that are CI in my research. But I still have never been one to just keep pumping unstudied compounds or mixtures thereof into my system.It is always a good idea to research the toxicology and the possible problems associated with compounds you take, and especially mixtures. Psychedelics that affect serotonin or NMDA also seem to be most problematic as rule of thumb. But the answer is that yes, you may have changed your brain chemistry. Hopefully, it will return to normal or near normal within a year if you are lucky.

While many people probably believe I am a wild man, I do not indescriminately pump anything I can get my hands on into my sytem, in large doses. And unike ETF, I do not take ketamine multiple times in my lab after getting caught once (he got thrown out of grad school because of being caught the second time.) And as someone who has seen ETF on ketamine more than once, I cannot imagine how he expected to not be caught. I tend not to show my opioids compared with most people-most likely because of my high dose long time use-but I know better than to shoot a bunch of cocaine or 4-Methyl-Aminorex in my lab and go around other pharmacologists or physicians, some of whom are also experts in drugs of abuse.

My suggestion is to try using some high dose antioxidants for a while ASAP like SAMe, Gingko, Vitamin E or Resveratol for a few weeks to try to reverse the likely type of damage. Be careful next time. Read all you can about the drugs you are taking and try to reduce the harm they cause.

Finally, some drugs last directly for a week but rarely much longer. If this persists for more than a week, it is likely there is a change, but start the correction with antioxidants on day 2.
 
After a careless binge as they call it I would say it's not unnormal to have 3-6 days of mental unstableness. Im guessing the benzo is the reason for not giving a shit - benzos are kind of infamous for this reason alone so I would advise you to be careful to mix benzo and uppers. Many people having this lifestyle often to breakins waking up the next morning not remembering anything with a stereo between their legs, not remembering from where. Stealing cars and shit.

Eat healthy and stay away from stims for some days. You being aware of the changes I would say is a good sign. Different benzos have different halftimes, that is, some takes 72 hours before being out of your system. That is - you eat a pill and the effects of it will last for 72 hours. Others are shorter, others are longer. Also benzo seems to make one forget, so you might even eat some more without really recalling so extending the period...
 
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