While I appreciate the sentiment here, such attitudes are antithetical to the ultimate political goal of worldwide drug decriminalization that I presume we share, to a greater or lesser extent. There's no question about it - mescaline is a potent hallucinogen that is capable of producing mental states that are behaviorally indistinguishable from psychosis. Now, we can compare the safety of piperazines and gin and peyote all we like, but don't you think that this legislation is at least a tiny step in the right direction? And what is the actual safety profile of cannabis and hallucinogenic fungi, anyway? I highly doubt that controlled trials would report either one to be safe for public distribution by today's food, drug, and cosmetic standards. But that isn't the (political) point. Whether or not these drugs have been 'adequately' tested by a federal authority should have no bearing upon an individual's consumption of their particular substance of choice, harmful or not...or at least that's the libertarian tack. True, a more sensible approach would involve extensive (yes, probably unethical) animal testing and approval procedures - but that would only serve to put a stranger spin on the criminal underworld that we suffer today. Drug's that are federally 'banned' or officially deemed unsuitable for human consumption would still have to be regulated to such a degree that new underground markets could find an insidious niche in the production and distribution of Generally Recognized as Unsafe compounds. If criminal organizations began to thrive on such, what would fundamentally distinguish their role in society from the meth chemists of today and the bathtub gin-brewers of yesterday (note that I'm not talking strictly about organized crime here)? Recall the tired maxim that if people want it, they will tend to find it, purchase it, and consume it in direct proportion to the depth of their desire.