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  • BDD Moderators: Keif’ Richards

tramadol not working the same way on me as before, any help??

utrop

utrop

Greenlighter
Joined
Jun 21, 2010
Messages
38
First of all if somebody is going to criticize my question etc, finding it silly or whatever, that person better bite his/her tongue and shut up. Yes any help, tramadol feels weaker now, I need it for pain relief and my body is quite used to it now. DOn't know about fake trams we get that a lot nowadays. Or maybe I have to start using some good potentiators. Appreciate any help or advice.
 
Are you prescribed them? Or acquiring them through another means? How much are you taking per day?
Tolerance is a problem with all drugs and tramadol doesnt do anything for me anymore even at high doses. If you are a chronic pain patient and tramadol is no longer doing what it should, you need to talk to your Dr about switching to different meds. When tramadol stopped working for me my Dr put me on dihydrocodine 30mg for 6 months, then i went back on tramadol and it worked fine again.
 
I'm facing the problem you are...

I'm Rx'ed 50-100mg 4x per day (100mg 4x/day (400mg/day)), and have been on this since Feb. 2011. It's gotten so bad that I've switched to 200mg 2x per day and do my damnedest to keep from dosing a 3rd time. My doc won't budge on this Rx for some reason, so I get to just suffer. I really don't have any advice for you except to try and make yourself go through a drug holiday where you don't take any of your tramadol for about a week. I tend to go 1-2 weeks each month in between my Rx without anything, so that kinda helps with my tolerance, but not by much.

Anyways, I wish you luck. Chronic pain is a bitch of a problem, and can affect many areas of your physical and mental health. Stay strong, my friend.
 
Because 400mg is the maximum safe daily dose of tramadol. Anything above runs a risk of seizure. If 400 isn't working for you then your meds need to be changed. There's plenty of alternatives to trams.
 
Consider yourself lucky that tramadol ever did anything at all for you. For alot of us, it doesn't do anything at all.
 
Ya same thing happened to me. It worked when I was taking low doses but then when I started taking higher doses it stopped working completely and just gave me a headache. Weird.
 
Tramadol can be rally bad news, I was having the same problem, unable to get anything from a regular dose of tram. I ended up taking 700 mg throughout a couple hours and had a nasty grand mal, it lowered my seizure threshold to the point where even after I stopped taking them I was still having seizures and was finally diagnosed as epileptic. Its sad that doctors write a script for something as horrible as this... An opiate is an opiate and there are much safer ones. To the OP: Sorry I cant help more, just please listen to everyone and dont take more than 400 mg a day, Id recommend trying to get on a real opiate, even poppy pod tea is so much safer (IF youre going to take opiates everyday that is), and poppy pods are always readily available for sale on the internet. Either way, best of luck to you :)
 
Yeah, tramadol is a tricky bitch.
When I was doing very little of opioids (that is tramadol rarely and codeine from time to time, also not too often) it was MAGIC. Later when I was doing PST, even with nodding doses, I found that to be less euphoric than tramal.

When I got addicted to said PST, I still sometimes had great time with T. Sometimes. It's the key word here. I don't know what it was dependent on, but once I took 200mg, felt cozy and had this nod-like night, the other time I took 400mg and didn't feel too much.

Recently (I've kicked PST but I'm still doing weak opiates) I got myself a box of T. and I was doing doses of up to 700mg an evening (if you're new to T. don't take this much!) and felt it strong only once, with 400mg as far as I remember, other times were "meh..."
 
All you can really do is abstain for a little while. In my own experience, tramadol doesn't have much cross-tolerance with other opioids. There have been plenty of times when I was temporarily out and used various other opioids to mitigate withdrawal from tram. Codeine, hydrocodone, oxycodone, even methadone. As soon as I got tram back, I noticed tolerance had gone down considerably. Other opioids dont even help tram w/d symptoms 100% except for methadone which helped tremendously, but I would never touch it again.

But...you're in pain. Only thing you can do is talk to your doctor about it.
 
Thanks a lot my friends, appreciate your help, forgive me, replying almost a year after. I had strong doubts on fake pills but also maybe that manufacturers are not making it the same way as B4. I know ativan got that problem. I am not a user of ativan but this s from what ativan users told me, it's not the same anymore.
 
Dread calm said:
Because 400mg is the maximum safe daily dose of tramadol. Anything above runs a risk of seizure. If 400 isn't working for you then your meds need to be changed. There's plenty of alternatives to trams.
Click to expand...

Seizures from tramadol are not dose dependent according to one study.

Mean tramadol intake does not differ between patients with and without seizure, and the most common dose range in those with seizure is 500-1000 mg. We thus conclude that the incidence of seizure with tramadol is not dose dependent.
Click to expand...
Source:http://www.ncbi.nlm.nih.gov/pubmed/19415589
 
But higher doses will still be more likely to cause seizures even though some people might have bad luck and get one at the recommended dosage...

Get switched to tapentadol instead.
 
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^even less. Ive read accounts of people passing away as a result from the seizures with doses as low as 50-75mg. Fucking crazy.

It comes down to individual chemistry. For eg i can use a couple of grams at a time with no ill effect. And have done so countless times. I do not condone nor promote that by any means that isnt safe HR practice. This is just my experience with the drug for close to a decade.

This mightnt be a popular view but to be frank and honest, i think the seizure risk warning can be blown out of proportion as a lot of accoints of high doses by many on BL indicate.
 
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^ I've also used 2000-4000mg tramadol on several occasions (probably like 100 times at least). Out of all these times I only had a seizure once and that was when I didn't use clonazepam at the same time.
 
^ everyone's different. I almost died because I was driving on the highway when I had a seizure. Tramadol is not safe over 500 mgs and that's pushing it. I would talk to your doctor about an alternative.
 
I really miss the days when Tramadol actually worked good both as a pain-killer and a anti-despressiva. After going up to 700 mg with added anti-seizure medication (being prescribed 400 mg daily back then tho). I Got switched to 20 mg of OxyContin a few years ago (now I a at 120 mg a day, opiate tolerance sucks :p). However, I still miss the body buzz I had from it, I sometimes add a few to my Oxy and Morphine doses to potentate a little.

--» Peace o/
 
You can never avoid tolerance. Sure, somebody will suggest a potentiator or two, but then what? You bought yourself another month maybe if you're lucky? Tramadol has a ceiling and the risk of seizures so there's that. I don't mean to antagonize, but sooner or later you'll face the truth and you WILL have to take a tolerance break if you want it to be as effective as before. So either start taking something else instead, or take a tolerance break. As for potentiators there really isn't much in the end. If you want a more sedating effect you can take some benzos with it, but be VERY careful as this combination is quite dangerous. Other than that there's the usual antihistamine (Benadryl, Chlorpheniramine, etc) and then there's some anecdotal stuff like fruit juice, tonic water with quinine, baking soda, Tagamet, etc. which I personally never found them to work with opiates.
 
^ Yeah you're correct. Some of them are inhibitors of enzymes that break tramadol down, and with tramadol you need inducers rather than inhibitors to assist the conversion to M1.
 
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