DextromethorFan
Greenlighter
- Joined
- Jul 17, 2009
- Messages
- 15
The Areca Catechu (ARC) palm renders so-called 'betel nuts' -- fruits that contain seeds -- which have psychoactive alkaloids (at least 9 structurally related pyridine alkaloids including: arecoline, arecaidine, arecaine, arecolidine, guvacine, isoguvacine, guvacoline, and coniine). Peoples have been using the known carcinogen for years. The seed is chewed with CaOH to convert the alkaloids within to freebase for improved sub-lingual absorption.
A study shows that:
From that, could one say that the ARC seed alkaloids could undergo acid/base extraction and then insufflated to bypass digestive enzymes from converting the ARC seed material into carcinogens?
A study shows that:
http://dspace.nehu.ac.in/bitstream/1/3546/1/720.pdfTumour induction in any tissues was not observed when ARC or areca-nut extract was administered through the IP route [1,17]. Therefore, it seems that metabolic activation of ARC is needed for the final conversion into the ultimate carcinogens...
From that, could one say that the ARC seed alkaloids could undergo acid/base extraction and then insufflated to bypass digestive enzymes from converting the ARC seed material into carcinogens?