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  • BDD Moderators: Keif’ Richards

Drugs that potentiate alcohol

A

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Greenlighter
Joined
Apr 29, 2012
Messages
5
I take antipsychotics and one of the side effects is that it completely blocks the effect of alcohol. By this I mean that I can drink 10 beers and I won't feel a thing. The same is true for benzos. However, I went on Zoloft a little while back and while I was on it I could feel alcohol. Unfortunately I had to go off of it because it messed with my other symptoms.

I was wondering if anyone knew of any drugs that potentiate alcohol like SSRIs. Maybe not through the same mechanism of action, but drugs that make you feel the effect of alcohol more. I have done some research but haven't been able to find anything. Any help would be appreciated.
 
There are a few drugs that will potentiate alcohol, but they either lead to liver damage or increased risk of overdose when combined with alcohol.

Alcohol is so cheap, in interest of HR, I would just consume slightly more alcohol instead of trying to potentiate.
 
well anything that potentiates alcohol is likely to be a dangerous combo as they will most likely be depressant drugs too which can lead to a fatal cocktail of drugs all together.

benzodiazepenes act on the same receptor of alcohol, GABA, and of which you would have to drink less alcohol in order to get drunk, but it would be much easier to black out and consume too much.

apart form that i can't help you. try drinking harder proof liquor. or take ghb.
 
Please don't try to potentiate poison...errr..sorry.. alcohol.

harm reduction reply for today: check.

~token
 
indeed, there is no point in potentiating a poison. there aren't any safe methods that i know of either in order to boost the effects of alcohol. most will leave you dead as your loss of inhibitions from the alcohol will make you want to dose more of the drug you used to potentiate, or drink more alcohol. don't do it, or drink more if youre really desperate.
 
I don't get the big deal with alcohol. A nice beer to cool off is awesome. But I hate the feeling of being drunk...
 
Benzos or Pregabalin are the best way of potentiating alcohol, imo. The combination will lead to increased tolerance, addiction, physical dependence, blackouts, amnesia, motor ataxia, faster intoxication, etc if overdone.

They are very synergistic, so 1 + 1 =/= 1, it's more like 1 + 1 = 3-4, so I would take no more than 0.25-0.5mg Xanax or no more than 5-10mg Valium with your reduced alcohol amount, maybe 25% of what you normally drink (seriously, lol).

He's going to do it anyways, so we might as well show him how it's safely done in the spirit of HR.
 
Be careful using alcohol when you are obviously suffering from some level of depression it can really creep up on you. I ended up drinking 20 units a day for well over 2 years and just got more and more depressed.

I've stopped drinking now but am left with a Benzo issue which is proving difficult to deal with, and that started because the booze was no longer enough not matter how much I drank, when you drink everyday, heavily you don't get "drunk" I could down half a liter of whiskey and walk and talk like I'd had nothing, and get up the next day and go to work all day, that's when your in real trouble oddly enough, all the time your still getting to feel sick or having a serious hangover it's unlikely you've got a real problem IME.

Mixing benzos and booze is a very bad idea for so many reasons, not only is it dangerous but you end up with 2 nasty habits, Benzos seem so benign but they are far from that in reality.

You will honestly feel better if you stop drinking altogether and you will benefit fro your medication more, I'm not preaching I've done it all myself and still do some of it today:\
 
the main reason you arent feeling the effects are because the anti-psychotics you are on block the production of excess dopamine in the brain, which is a receptor which alcohol targets. it could also be switching off your gaba receptors at the same time, hence why you don't feel the effects from benzos or alcohol. benzos act on the gaba pathway, so i am presuming that it is doing both at the same time.

which anti-psychotic is it that you are taking? it could be a reuptake inhibitor which essentially will cancel the effects out from your alcohol/benzos as that is the primary receptor they work on.
 
ErgicMergic said:
Benzos or Pregabalin are the best way of potentiating alcohol, imo. The combination will lead to increased tolerance, addiction, physical dependence, blackouts, amnesia, motor ataxia, faster intoxication, etc if overdone.

They are very synergistic, so 1 + 1 =/= 1, it's more like 1 + 1 = 3-4, so I would take no more than 0.25-0.5mg Xanax or no more than 5-10mg Valium with your reduced alcohol amount, maybe 25% of what you normally drink (seriously, lol).

He's going to do it anyways, so we might as well show him how it's safely done in the spirit of HR.
Click to expand...

Point taken, honestly:)
yet, I won't retract.

-token
 
I hear heroin potentates alcohol pretty good, LOL.J/k Don't do that:D.Seriously don't.

What anti-psychotic are you taking. I can tell you that seroquel, risperdal, fluphenazine, or lithium do not block alcohol for me. Might make me more drowsy.

Do ten beers do absolutely nothing? Maybe your tolerance is too high, the anti-psychotics should make the alcohol stronger.

Really there is nothing that can be mixed with alcohol and anti-psychotics that won't cause potentially dangerous depressant effects. Yeah it's possible, I do it all the time, but who knows if what's safe for me will be dangerous for you.
 
Thank you for the replies. I am taking a combination of the antipsychotics Fanapt and Saphris. I used to take Zyprexa, which didn't work for me, but I could feel alcohol when I took that.
 
i think that alcohol has some effects on the 5-ht2p receptor of the brain, under which saphris antagonises and dependant on how long you have been taking anti-psychotics can affect your tolerance to alcohol greatly, meaning you require a lot more in order to feel any of the effects of it.
 
nootropics change the way alcohol feels as a whole...there is a fair bit of potentiation as well...but its a more "clearheaded" drunk...anybody whose drabk on nootropics can probably explain this better than me
 
Seriously whats cheaper than some crap wine or beer..? Why potentiate ethanol and risk liver damage when you can drink 2 more glasses...?
 
6apbhmm said:
Seriously whats cheaper than some crap wine or beer..? Why potentiate ethanol and risk liver damage when you can drink 2 more glasses...?
Click to expand...

Benzos are significantly cheaper than crap wine or beer if you buy them in bulk from 3rd world countries (1000pills+)

...but you probably shouldn't attempt to do that. it could easily result in serious jail time :\
 
ErgicMergic said:
Benzos or Pregabalin are the best way of potentiating alcohol, imo. The combination will lead to increased tolerance, addiction, physical dependence, blackouts, amnesia, motor ataxia, faster intoxication, etc if overdone.

They are very synergistic, so 1 + 1 =/= 1, it's more like 1 + 1 = 3-4, so I would take no more than 0.25-0.5mg Xanax or no more than 5-10mg Valium with your reduced alcohol amount, maybe 25% of what you normally drink (seriously, lol).

He's going to do it anyways, so we might as well show him how it's safely done in the spirit of HR.
Click to expand...

Pregablin will be your best bet OP.

Mixing benzos with alcohol is a good way to end up messing up your life or ending up dead.
 
Best way to potentate alcohol is with phenibut. It's legal, and you can order it online. It acts on GABA like alcohol. 1.5 - 2 grams will decrease your tolerance dramaticlly. I'm able to get pretty drunk with phenibut and a few beers. Just don't use it every day or you will build a tolerance to it rapidly.
 
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