30mg "Blues" Stuffed Nose issue

[blasph3my1]

Okay the title says it all.. I been doing 30mg "Blues" for about 8 months now about six 30mg blues every 3 days or so i do them, and for the past week or so everytime i bump it within 30 seconds my nose is just stuffed up to the point were i get a headache right away. So im curious can i be allergic now? ha does anyone else have this issue or have?

Thanks in advance!

 

[Tommyboy]

It could just be regular allergies. It's common for allergies to act up during this time of year, even if you don't have a history of bad allergies. If you were actually allergic to oxycodone, you would be experiencing more than just a headache and stuffy nose.

I recommend just eating the pills. Oxycodone has a higher oral BA compared to its nasal BA. I gave up snorting oxycodone a year or so ago, and even though the pills are pretty small, I certainly wouldn't be putting 6 of them up my nose if I was still snorting them.

 

[blasph3my1]

Yeah i was kinda thinking i could be allergies because the weather is changing.. out here in ct its been going from 30 one week.. then the next its 80 ha. But yeah i been thinking about chewing them now since my nose seems like its being abused.

It could just be regular allergies. It's common for allergies to act up during this time of year, even if you don't have a history of bad allergies. If you were actually allergic to oxycodone, you would be experiencing more than just a headache and stuffy nose.

I recommend just eating the pills. Oxycodone has a higher oral BA compared to its nasal BA. I gave up snorting oxycodone a year or so ago, and even though the pills are pretty small, I certainly wouldn't be putting 6 of them up my nose if I was still snorting them.

 

[Allein]

You may be atopic to some degree and some can become intolerant to almost anything due to exposure to it, I'd try the above but if you get the same result you may have to give it a break for a bit.

If you have history of condition like asthma or hay fever then this is quite possible, but also likely to be temporary.

 

[BiggDirty01]

I know for me that nasal swelling from sinus issues or snorting too many substances does not go away unless you stop using this ROA and use a saline spray to moisturize and irrigate the nasal passages.

And as Tommyboy mentioned above, you should really consider taking all oxycodone orally because you absorb so much more than any other ROA (except IV, but that is far too dangerous to be worth serious consideration)

Just my .02

 

[Pjkt2501]

I know for me that nasal swelling from sinus issues or snorting too many substances does not go away unless you stop using this ROA and use a saline spray to moisturize and irrigate the nasal passages.

This occurs with me as well; the inflammation. Saline spray works excellent - I do a "free" method however: while in the shower inhale very lightly with your face in the stream (more like chin / neck) and breathe in the "spray" from the shower head (only the light particulates). This keeps the nasal passageway hydrated as well.

OP: Oral BA IS higher, but I sympathize with you in terms of only wanting to sniff them.. I unfortunately tend to do the same.

Don't IV pills... baad road to go down.

 

[THC2LSD]

I personally think that small study that says oral oxycodone has higher average BA might be bullshit or it's not true all the time for all people.For me it feels at least 25% stronger. Plus that study showed it peaked in 15 minutes vs 1-2 hours with oral. That's why people sniff them.

It would be best to take them orally, it still works pretty good for most people, but if you do snort oxy use a clean surface and a clean straw(fresh 20 could work but even then it's got a lot of germs, clean straw is better). What works for me is flushing the sinuses with saline water. If you can stand the taste sublingually might work, though there are studies that show it's not better than oral, I think the subjects might have just swallowed the bitter oxy too quick, that's just my opinion.

 

[BiggDirty01]

So are you saying its preferable to get a quicker rush (and thus a shorter duration) over the steady and continuous rush that oral oxycodone provides.

I'm sorry but your logic reminds me of the folks who prefer smoking oxy because "it hits you right away". I know opiates and addiction in general are a instant gratification business but my god if we cant acknowledge the scientific fact and longer period of time oral oxy provides than I guess I am an 'atypical' oxy addict.

Not trying to be a dick, just confused about the rationality.

 

[GABAking]

^I agree with THC. I always research drugs thoroughly before I use, and oxycodone is the only drug that I continue to take nasally rather than orally, despite its lower BA. Eating it just doesn't provide that same satisfaction as snorting.

BiggDirty, when you write it like that, you make it sound like it's ludacris. It's personal preference. I prefer a quicker peak (thus shorter duration) rather than slow onset and peak 2 hours later. Everyone's different. What's irrational to you makes sense to others, y'know?

 

[THC2LSD]

It's the same reason people use beer bongs, gravity bongs, drink liquor vs. sipping on a beer or slowing enjoying a joint. The faster drugs get into the brain the more euphoria they provide. The faster they enter the brain the more euphoric. Think methadone vs. heroin. You could say why doesn't everyone get on methadone, it's an opiate with a slow onset and long duration, shit why bother with oxy when you could get on methadone. I suspect that for some people snorted oxy could provided higher brain levels mg for mg than oral oxy.For me snorted and even smoked oxy feels more intense than oral, though the duration for smoked is very short it feels more intense while it lasts than even snorted if done right.

If oral oxy works for you, more power to you. Orally is the safes way to take pills, oxycodone being one of the best oral opiates out there. But some people like a more intense high than oral can provide.

 

[nAON]

The BA thing is verified, oral is definitely higher. It's stronger because you're getting a higher dose over a shorter period of time - it's just not as efficient.

 

[THC2LSD]

Are you referring to this study(http://www.ncbi.nlm.nih.gov/pubmed/9062618)? They only had 3 males and 7 females from Finland, used an uncommon liquid preparation, and BA varied .34+/-. And they compared it to IV, not oral. They measured plasma levels, not brain levels. Other studies show oxycodone's oral BA is generally over 50%, usually 60-85%. Where does the rest of the oxycodone go, there is less first pass metabolism in the nose than the GI tracts? Maybe more reaches the brain, or maybe more is converted to oxymorphone. It's hardly as definitive as a drug trial with a 1000 people. Ancetdotely many people say sniffed is stronger.

If someone's body gets 85% oxycodone, the 15% extra will be barely noticiable save the much faster onset, but for people getting 50-60% BA it might feel twice as strong.

I find that using grapefruit juice makes oral oxycodone stronger and gives a longer duration, this is another option.

 

[BiggDirty01]

^
BiggDirty, when you write it like that, you make it sound like it's ludacris. It's personal preference. I prefer a quicker peak (thus shorter duration) rather than slow onset and peak 2 hours later. Everyone's different. What's irrational to you makes sense to others, y'know?

I wasn't dismissing your own preference I just was trying to point out that it seems odd that people would want to go against the grain in terms of bioavailability. While I don't doubt the rush from snorting oxy is fantastic (I've done it as well) I just was curious as to what the rationale would be knowing scientifically that you are absorbing more of the drug orally.

Maybe where I was really off was comparing it to smoking oxy; it obviously is much better/smarter to insuffulate versus smoke it.

Once again, sorry if I came off as a dick.

 

[Tommyboy]

It's the same reason people use beer bongs, gravity bongs, drink liquor vs. sipping on a beer or slowing enjoying a joint. The faster drugs get into the brain the more euphoria they provide. The faster they enter the brain the more euphoric.

No, they just want to get high or drunk using less of the substance. Smoking a bong is not more euphoric than smoking a joint, and taking shots does not provide a more euphoric intoxication that drinking beers. They just allow you to get drunk/high faster, but that doesn't make them more euphoric ROAs.

Think methadone vs. heroin. You could say why doesn't everyone get on methadone, it's an opiate with a slow onset and long duration, shit why bother with oxy when you could get on methadone. I suspect that for some people snorted oxy could provided higher brain levels mg for mg than oral oxy.For me snorted and even smoked oxy feels more intense than oral, though the duration for smoked is very short it feels more intense while it lasts than even snorted if done right.

If oral oxy works for you, more power to you. Orally is the safes way to take pills, oxycodone being one of the best oral opiates out there. But some people like a more intense high than oral can provide.

You are comparing two different drugs. People find different opiates to be more euphoric than others, and onset isn't the main factor. Even if all of the drugs were compared using IV as the ROA there is still going to be a preferance for some opiates over others. A lot of people don't find fentanyl to be that euphoric even when IV'd, yet it certainly has a quick peak and is extremely potent.

Are you referring to this study(http://www.ncbi.nlm.nih.gov/pubmed/9062618)? They only had 3 males and 7 females from Finland, used an uncommon liquid preparation, and BA varied .34+/-. And they compared it to IV, not oral. They measured plasma levels, not brain levels. Other studies show oxycodone's oral BA is generally over 50%, usually 60-85%. Where does the rest of the oxycodone go, there is less first pass metabolism in the nose than the GI tracts? Maybe more reaches the brain, or maybe more is converted to oxymorphone. It's hardly as definitive as a drug trial with a 1000 people. Ancetdotely many people say sniffed is stronger.

What are "brain levels?" Bioavailability has many different factors. Some drugs have a very high oral BA and a low nasal BA, while others have a very low oral BA and a high nasal BA, and everything in between. These aren't some bogus numbers either. People are given the drug via different ROAs, and the plasma levels are taken to determine the amount of the drug in the persons system. This number is compared to the numbers for the levels of the drug from the IV roa which has a BA of 100%. From there they calculate the numbers to arrive at the BAs for each ROA for a given drug.

 

[Kid Amine]

two guesses (other than overdoing it):

~ Generic formulations of roxy may have different ingredients than other generics. I got ahold of some 30s not long ago, teh ones V 4812 - Qualitest (iirc) makes em - seemed like they had a LOT of blue dye in them vs the Mallincrodt roxy. that could be one thing. another time I got some 15s I didnt recognize teh markings - they were real, but Caraco brand, and were like snorting sand- very abrasive mix (again, compared to the Mallincrodt ones).

Personally I always put a few drops of water down each nostril after snorting pretty much anything (30s included) to help flush out my nose and get the bio higher - I figure dry powder doesnt absorb well onto much of anything. I know that snorting is *usually* a lesser route with roxy vs eating, but for some reason nearly every time Ive had roxy, I had a big meal not long before, and I dont want the wait of the oxy in my stomach nor the 'randomness' of the absorbtion experience (will it take 30 mins or 2 hrs to start working? will I barely feel it or get high as hell? these are legit questions when taking most pills by mouth after a big meal).

I like 30s too but the prices here are insane, availability is low, and my tolerance is too high. Makes for an expensive high.

 

[oppie]

After a couple years of oxy snorting my nose was plugged from morning to night almost everyday. I would literally have to shove tissue and q-tips up there to clean my nose out before every line and wash it down with a lil water. I was doing around 3-6 80's a day. I was at 6 when I quit. Now I've relapsed here and there but everytime I rail them my nose gets fucked up for a couple days so yes I think I did permanent damage to my nose.

And for the oxy eater club out there once you head down the snorting road eating oxy's doesn't do shit for you. I was snorting 120mg at a time and if I ate double that I still wouldn't feel as good as my 120 line.

 

[BiggDirty01]

After a couple years of oxy snorting my nose was plugged from morning to night almost everyday. I would literally have to shove tissue and q-tips up there to clean my nose out before every line and wash it down with a lil water. I was doing around 3-6 80's a day. I was at 6 when I quit. Now I've relapsed here and there but everytime I rail them my nose gets fucked up for a couple days so yes I think I did permanent damage to my nose.

And for the oxy eater club out there once you head down the snorting road eating oxy's doesn't do shit for you. I was snorting 120mg at a time and if I ate double that I still wouldn't feel as good as my 120 line.

Your claim doesn't hold water scientifically.

According to http://www.bluelight.ru/vb/threads/266339-Bioavailability-Half-life-MEGA-Thread

The highest bioavailability intranasally is 70% while orally goes as high as 87%

Now the rush may be better and quicker from snorting oxy, it is without a doubt impossible to suggest that eating oxycodone "doesn't do shit for you". Especially if you are having issues with your nasal passages.

Just a heads up bro.

 

[oppie]

Ok so scientifically I should get higher eating them I know I've read that years ago, I was just saying that after you've been snorting oxy's for a long time(I did for 2 years everyday) every couple hours, wake up one morning and say I'll eat all my oxy today....that day will feel like your in withdrawal all day. Maybe because you eat a single dose maybe 2 or 3 and say that's it for the day, I couldn't do that if I went 4-6 hours without my dose I would go through the acute withdrawal, meaning I would start sweating and generally feel like shit. It was just a waste to me to eat it, I literally wouldn't feel shit. I was pretty deep into addiction and eating oxy's wouldn't cut it I don't know what else to say but I'm not just making this up I know others that have had the same experience. This is coming from people that snort oxy's a lot for years, I don't know how many people like that you know but try and convince them that they will get higher by eating oxy's and they will disagree.

 

[tricomb]

Your claim doesn't hold water scientifically.

According to http://www.bluelight.ru/vb/threads/266339-Bioavailability-Half-life-MEGA-Thread

The highest bioavailability intranasally is 70% while orally goes as high as 87%

Now the rush may be better and quicker from snorting oxy, it is without a doubt impossible to suggest that eating oxycodone "doesn't do shit for you". Especially if you are having issues with your nasal passages.

Just a heads up bro.

This ^ People should not snort oxycodone just because they can, if I were prescribed roxicodone I would take them orally, as that is the best way to get desired effects, duration, analgesia, euphoria, etc.

All IV oxycodone provides is instant onset, not any more intense than the peak of an oral dose, maybe even less so. It's worth waiting 15 minutes for your instant release oxycodone to kick in orally.

 

[Pjkt2501]

BA is a measure of analgesia effect as well, not how nice they are when abused. Meaning that oral oxycodone provides 87% the pain relief as IV oxycodone does, and nasal about 60%. These figures don't speak to abuse at all. Yes, it translates somewhat, but that's not the main goal there.