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Opioids Snorting Pills With Bloody Nose So It Hits Faster and Harder

C

curioushat

Bluelighter
Joined
Feb 28, 2011
Messages
150
Hello all,

I have a serious question. I am looking to snort some powder to get high, I would like it to hit me faster than normal. If I had cuts in my nose before snorting (bloody nose), would it enter into the bloodstream faster? I imagine the answer is the same regardless of the substance, but I am asking specifically about opioids (oxycodone). I am thinking that more of the oxycodone would enter immediately into the bloodstream through the cut(s), then the rest absorbed into the nasal cavity.

The bioavailability would also be higher, am I correct?

Thank you for serious scientific factual responses only. I am aware that this is not the healthiest way of ingestion, nor is it "necessary".
 
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Please don't use any varians of SWIM, "that person" still is a violation of our user agreement, please read it now as well as the OD guidelines, there is a link in my signature.

Having a bloody nose if anything will decrease the nasal bioavaliability. This of it like this, if you cut your arm then put oxycodone on the cut, do you think it would work? I highly doubt it, since a cut is a break in your skin, resulting in pressure pushing out, which is why you bleed out.

In your nose, drugs are absorbed through your epithelial membrane.
 
tricomb said:
Please don't use any varians of SWIM, "that person" still is a violation of our user agreement, please read it now as well as the OD guidelines, there is a link in my signature.

Having a bloody nose if anything will decrease the nasal bioavaliability. This of it like this, if you cut your arm then put oxycodone on the cut, do you think it would work? I highly doubt it, since a cut is a break in your skin, resulting in pressure pushing out, which is why you bleed out.

In your nose, drugs are absorbed through your epithelial membrane.
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Thank you for the response. In the future I will be more careful to ask the questions on the behalf of myself.

I have been curious about this for a time, so I am thankful for a thoughtful response.

EDIT: Also, it is interesting that you spoke of cutting your arm and putting the oxycodone in the cut. I have actually tried this with Opana (since the BA is low for intranasal and oral), and I nnoticed an intense, short rush. I made a small cut on my arm put in the powdered Opana. I used a pair of scissors to "force" the opana into the cut and into my bloodstream. I do believe it worked effectively. However that may have been placebo. I am going to try this now with ~20mg of oxycodone and will report back the results.
 
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OP, this sounds like a very BAD idea and an easy way to develop an infection. Using open wounds as a means to force non-sterilized powders into your blood stream is likely to not only not work (as TRI just mentioned) but you are asking for bacteria on the pill or your hand from also entering the wound. Oxycodone has a ~90% oral bio availability.

Please just swallow your Oxycodone!!
 
curioushat said:
Thank you for the response. In the future I will be more careful to ask the questions on the behalf of myself.

I have been curious about this for a time, so I am thankful for a thoughtful response.

EDIT: Also, it is interesting that you spoke of cutting your arm and putting the oxycodone in the cut. I have actually tried this with Opana (since the BA is low for intranasal and oral), and I nnoticed an intense, short rush. I made a small cut on my arm put in the powdered Opana. I used a pair of scissors to "force" the opana into the cut and into my bloodstream. I do believe it worked effectively. However that may have been placebo. I am going to try this now with ~20mg of oxycodone and will report back the results.
Click to expand...

Wow buddy, take a step back. I assure you that if you cut yourself and put opana in the wound, anything you felt was most likely placebo, as there are many reasons why this wouldn't work. Mostly due to the pressure pushing out due to your body's own self defense mechanisms.

As mentioned, orally is the best way to take oxycodone, as directed. I guarantee you anything you feel by cutting yourself is mostly psychological. I can't imagine a bioavailability being anything higher than 5-10%, making that the worst possible way to take a drug. Just take it orally.....Do not self-mutilate!!!!?

You can't make a new, efficient ROA. Apparently there are reports of other people doing what you did, but it's highly inefficient as an ROA.
 
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tricomb said:
Wow buddy, take a step back. I assure you that if you cut yourself and put opana in the wound, anything you felt was most likely placebo, as there are many reasons why this wouldn't work. Mostly due to the pressure pushing out due to your body's own self defense mechanisms.

As mentioned, orally is the best way to take oxycodone, as directed. I guarantee you anything you feel by cutting yourself is psychological. Do not self-mutilate!!!!?

You can't make a new ROA.
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Eh, I doubt it was all placebo, as some of it would still get absorbed into capillaries/lymphatic vessels, just not necessarily the ones he cut--like how a missed shot will still get somewhat absorbed. It definitely wouldn't provide a rush, though.

Not that I'm recommending ever doing that, it's certainly a bad idea.
 
Yeah I editted my post to explain what I meant. Maybe a TINY bit got absorbed, oxycodone is not very lipophillic. That's why I think it's mostly placebo, with maybe 10% BA and I feel like even that is generous.
 
Yeah cutting your arm to administer drugs is just going to waste your drugs. If you're so concerned about the rush, just snort it, or even better, plug it. I would never recommend IV use to anyone because of the even bigger addiction monkey that comes with it.
 
I think the rush you experienced with opana was more a rush from self harm. You wouldn't have absorbed the drug. If this is something you are doing I would reccomend psychiatric help.
 
madog11 said:
I think the rush you experienced with opana was more a rush from self harm. You wouldn't have absorbed the drug. If this is something you are doing I would reccomend psychiatric help.
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I don't do this regularly, I've just done it a few times before. The self-harm rush makes sense. It's probably true too. I feel like an idiot for asking this question.

Thanks for the factual replies.
 
You would be an idiot if you didn't ask about a question like that, you're no idiot.
 
def Plug ya oxys broooooo :) If u dont wana go IV/IM way and want to get better BA's try crushing it, add 3-4mls of warm water use a oral syring and insert it in your ass. about 2knockles deep. then push the plunger ;D
 
^ have to agree with this.. plus dont cut yourself up. thank you.

also, can we change the title so its not so gross sounding someway? like "Alternate ROA's through cuts?" i think is gross thinking of snorting anything with a bloody nose. it could just be me tho.
 
this actually happened by accident to me once.

i was leaning down to the table to snort a line of heroin. i put the straw in my nose as i was leaning down to the table and misjudged the distance, that and i was in some bad withdrawal and couldn't wait to get that powder up my nose. anyway, i lowered my head to fast and stubbed the straw on the table jamming it inside my nostril and got a bloody nose. i still had to snort the best i could with that nostril as my other one was totally clogged.

i was hoping for the same thing you were asking but i barely felt anything. most likely any blood that is in the nostril will catch the powder and stop it from absorbing completely.
 
acid_staind said:
this actually happened by accident to me once.

i was leaning down to the table to snort a line of heroin. i put the straw in my nose as i was leaning down to the table and misjudged the distance, that and i was in some bad withdrawal and couldn't wait to get that powder up my nose. anyway, i lowered my head to fast and stubbed the straw on the table jamming it inside my nostril and got a bloody nose. i still had to snort the best i could with that nostril as my other one was totally clogged.

i was hoping for the same thing you were asking but i barely felt anything. most likely any blood that is in the nostril will catch the powder and stop it from absorbing completely.
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This is what I thought would happen, it'll coagulate and lower the BA significantly.
 
honestly i think the bioavailability of oxy on a cut would be absolutely zero because your body is designed to not let any foreign matter enter your bloodstream from an injury....oxycontin on a thumb tack? maybe...lol please do not do that
 
weekday warrior said:
honestly i think the bioavailability of oxy on a cut would be absolutely zero because your body is designed to not let any foreign matter enter your bloodstream from an injury....oxycontin on a thumb tack? maybe...lol please do not do that
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my thoughts. I thought a 5-10% BA was generous due to the external pressure. If your body absorbed much from cuts and just released it into the bloodstream, we'd be fucked from infection.
 
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