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  • BDD Moderators: Keif’ Richards

How do different doses of bupe compare & how long can I take it with minimal w/d

A

Anon54

Ex-Bluelighter
Joined
Jun 11, 2010
Messages
861
I quit regularly use codeine 400mg-600mg & use & do oxy about 40mg-120mg.
anyways I got given some bubs & wondering about how different doses work
buprenorphine has a ceiling effect at 32 mg according to wikiepdia but does that mean the last 8mg is as strong as the first 8mg if u know what i mean?
Im quitting cwe because I got a liver function test done & my enzymes were slightly off balance probably due mostly to the soluble apap but also the codeine maybe but like i said im not taking the bupe just for the codeine w/d. Im trying to relax but dont want to get addicted. I only have 8 but can get more though.
I've had 16mg today & I dont feel great but certainly feel better. im just a bit more relaxed. I have another 16mg in my mouth atm. So im taking the ceiling dose because I think I can easily handle it. Yes I understand that is it's a high dose but im only feeling a little relaxed from too. Im not falling asleep or anything.
Is taking 32mg dangerous at all?
If I take 16mg-32mg of bupe every day how long could i take it for with stopping it pretty easy. or atleast with a half the dose for a day taper?
IIm guessing I could get away with 5 days but taking it for a week would be pushing my luck. I hope ya cant get w/d from just taking it for 4 days. Anyways its helping my c/w. a bit overkill but I was diagnosed with GAD & these pills some to be calming me down.
Someone I know has a script for temazepam & Valium so im going to be buying some of which ever benzo I decide. I usually take large doses of benzos. usually around 100mg of valium or 200mg of temazepam.
Is it any more dangerous to mix benzos with bupe than it is with oxy?
Ive mixed them with oxy before with no problems. benzos honestly practically have no effect on me.
btw I here ppl talking about "PAWS" When they get opiate w/d.
Can someone explain to me what PAWS means please?
 
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quoted by xHippiexchildx in the sub mega thread:
Opiate addict: Doctor, i'm a pain pill addict. Can you help me?

Suboxone doctor: Sure, I'll just give you this prescription for suboxone. It's 100% totally safe. We'll start you off on 32 mgs a day, even though it stops being effective after 8mg. Then, whenever you want to come off, just taper down. You may have to cut the pill with a razor blade to get the correct dosage, or do some extraction methods on it. But other than that, you'll do fine.
Click to expand...

Is there any truth to this. Am I wasting good medication by taking 32mg like I am now?
if 32mg is only 10% for example more effective than 8mg than it would be waste

Edit: this pills have no dose written on them. he said they were 8s. but wouldnt i be passed out if they were really 8s?
 
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Basic dosing question OD --> BDD


Please read their posting guidelines, we don't do substance ID's on bluelight a simple google search will sort that out.
 
You should be able to drop from 32mg down to 8mg per day without any discomfort. You're receptors will be saturated, and you definitely don't need to be taking 32mg a day, let alone in a single dose, based on your previous oxy/codeine use.

It's no more dangerous to mix benzos with buprenorphine than it is with other opioids, but is still dangerous nonetheless, and especially in the amounts you're taking.

And PAWS is Post Acute Withdrawl Syndrome, basically an aggregate of symptoms users experience after the acute withdrawl symptoms have subsided. Do a search for more info.
 
well i must say im pretty impressed with the way Subutex is working. I dont feel high yet I dont feel sick.
Usually i would feel really sick on a day like today. Ive had no sleep cuz i was up all night cuz i had a point of meth (Ice) & had 120mg of oxy too.

I rarely do meth & i never really think it's worth it & every time I take it I dont ever really feel the need to do it again which is good. So basically its only been a few times a year over the last 6 years or so ive touched it.

the subutex may be more addictive than the codeine im addicted too. (I only use codeine & valium on a fairly regular basis. I dont drink) but i wont be getting any soluble apap. Because my hope is to live a happy healthy life.

Ive been told my liver isnt 100% so im not gunna fuck around & plan to change my life style. im just going to do it now while it's not to late.
 
so let me get this right. as u up the dose the effects increase slower & slower?
your first 8mg is the strongest. if u have another 8mg it wont be twice as strong. maybe 3/4 stronger.
than if u have another 8mg the effects will increase even slower maybe 3/5.
next 8mg 1/2 stronger than the increase of the last 8mg
not the exact fractions of course but is that kinda how it works?
anyone know why the ceiling dose is 32mg?

i'll do some research myself now... but if i cant find anything im just interested
 
Careful, Anon, you're playing with fire with those subs. We'll probably see 5 threads a day from you about how to quit subs in 6 months if you keep that up and don't take the advice we've given you in your 9000 threads in BDD.

Bupe is stronger, and has a higher ceiling dose than codeine. Plus, its long half life makes dependence and tolerance catch on much faster.
 
^^hmm u know actually kind of make me think for a second. maybe when i take my last 2 tomorrow i should leave it at that. i mean im only really addicted to codeine. subs are a bit over kill. cant help my addictive personality. I have GAD & depression & the subs have really cheered me up today. dunno what i would have done without them

truth is u'r right. like my dr who doesnt wanna give me benzos no more. because yeah i wouldnt even think twice about not abusing them :(
I used to get prescribed 5mg a day valium. Now when I often buy them I take over 100mg. But Im not addicted. guess thats the same logic im using with the subs. wont happen to me. & the sad thing probably is i actually dont think it will happen to me. if that makes sense. i think i just contradicted myself
 
ErgicMergic said:
Careful, Anon, you're playing with fire with those subs. We'll probably see 5 threads a day from you about how to quit subs in 6 months if you keep that up and don't take the advice we've given you in your 9000 threads in BDD.

Bupe is stronger, and has a higher ceiling dose than codeine. Plus, its long half life makes dependence and tolerance catch on much faster.
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He speaks the truth, brother... I've been struggling to come off of that shit for a long time and so have a shit load of other people on BL. Getting your doses down from 24 or 16mg to even 4mg isn't that big of a deal..but once your down to like 1 or 2mg a day, coming off becomes much harder. Take all the suboxone withdrawal threads and the fact it has it's on megathread as a hint. It's a temporary band aid that turns into a fifty pound weight attached to your bloody ankle.
 
The effects are not going to increase slower, and slower as you go up. Rather they will NOT increase at all.

Bupe is very strong. You only really need very small amounts to keep off withdrawal, and the less you take the more of a chance you have of getting high.

It's only a partial agonist. It's going to fill all your receptors, not make you sick or high, and block any other opiates from binding.

There is no need to take 32 mg of suboxone. It's a huge waste.
 
You get MUCH higher when you get your bupe dose below 2mg per use.

I was once on 16mg a day back in my teens, and barely felt each dose because my receptors were always so saturated so I didn't get any euphoria - which is associated with the increasing levels on bupe after each dose.

I went down to 1mg three times a day and felt it much better.

Then I quit for 3 days, went into withdrawals, then took .5mg and was completely high like I had taken a strong dose of hydrocodone.

The lower the dose, the quicker your body eliminates the bupe after each dose, therefore the bigger increase you'll feel after each dose, hence increased euphoria.

You can drop from 32mg to 8mg in a week. Tolerance adjusts extremely fast with bupe both up and down.
 
2mg and under allow for the liver to produce and utilize norbuprenorphine from what I understand; this is the chemical that allows for a "high." If you're constantly dosing at 3mg, you'll rise above this point quickly and just get the same effect as if you took way more (assuming you don't NEED the huge amount to come off a serious dope habit: grams per day).

How much codeine do you take per day? 400mg? At that level I'd still suggest taking 1mg of bupe at a time until relief is achieved. Day 1 will be tough getting this sweet spot; it takes like 45 minutes for sublingual bupe to take effect.

When I'm responsible w/ bupe, I just use 2mg once, then .5-1mg per dose (usually 1/day) until I can either hop off, or want to use my DOC again.

Good luck! (32mg is far too much; 1mg would have prob done you fine, maybe 2. Bupe doesn't behave like typical opiates for the most part.)
 
CitioKid said:
You get MUCH higher when you get your bupe dose below 2mg per use.

I was once on 16mg a day back in my teens, and barely felt each dose because my receptors were always so saturated so I didn't get any euphoria - which is associated with the increasing levels on bupe after each dose.

I went down to 1mg three times a day and felt it much better.

Then I quit for 3 days, went into withdrawals, then took .5mg and was completely high like I had taken a strong dose of hydrocodone.

The lower the dose, the quicker your body eliminates the bupe after each dose, therefore the bigger increase you'll feel after each dose, hence increased euphoria.

You can drop from 32mg to 8mg in a week. Tolerance adjusts extremely fast with bupe both up and down.
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so im trying to use them recreationally cuz i only have a few. what dose would u recommend. 1mg?
its gunna be hard to cut an 8mg in to 8 peices.
anyways once i know the dose i also need to know how often I should re-dose to be as effected as possible?

It doesnt make sense. I can understand 4mg giving u the same high as 1mg. but i dont understand how 4mg would give u less a high. I wonering why they have 8mg tablets when they are weaker than the 1mg tablets
 
Just saying, man, you're going to get a lot more euphoria at doses under 2mg. You seem to be going through a rough patch, which is the worst time to experiment with euphoric drugs, especially ones as readily available as Subs. You haven't opened pandora's box yet, why risk it?

Low doses of bupe act as a prodrug to the full agonist Norbupe, which is a bonfide, full-agonist opioid. The reason you aren't getting euphoria right now is due to the binding affinity of bupe; that affinity is so high with bupe (partial agonist) that doses over 2mg saturate the opioid receptors, making getting high from Norbupe impossible.

You haven't opened Pandora's Box yet, so why risk it? You can walk away right now and save yourself a lot of heartache.
 
Anon54 said:
It doesnt make sense. I can understand 4mg giving u the same high as 1mg. but i dont understand how 4mg would give u less a high. I wonering why they have 8mg tablets when they are weaker than the 1mg tablets
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Active metabolites, and the vacancy of an opi receptor left after an addiction.

To elaborate: the metabolites of buprenorphone (particularly norbupe) is what gets you high. When you take doses less than 2mg, norbupe gets a look in at your receptors. Above 2mg, it's just the regular stuff (which provides no real euphoria).

A heavy dope habit leaves a large crater to fill, so to say, which 1mg likely won't fill - leaving WD still present. 4mg will fill this and leave a user feeling "baseline" to okay. From there the dose is worked down to 1.5-2mg (imo, the sweet spot) and slight peaks and dips are felt allowing for a subtle high.
 
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