etizolam

[phsycra]

Hi

I know its said that 1mg of etizolam is equal to 10mgs of Valium but I've read that 4mgs is the od threshold I'm on 3mgs now and not feeling anything is it safe to take more?

Thanks

(changed to etizolam - effie)

 

[Venrak]

What is your benzo tolerance like?

Also, benzos aren't recreational IMO. You may not get euphoria from them. Are you perhaps just feeling sedated and calm?

 

[FlippingTop]

it is etizolam btw.

I find that all these benzo comparison charts are a bit stupid. Benzos do not feel the same, maybe an addiction to 1mg etizolam a day is equivalent to 10mg diaz if you are tapering, but apart from that the charts should not be taken as the gospel truth.

4mg is not the OD level either... I ate 10mg last night with no benzo tolerance and I slept well and feel fine.

you can only OD on benzos when mixing them with other drugs (unless you go OTT obviously...)

 

[pally pete]

it is etizolam btw.

I find that all these benzo comparison charts are a bit stupid. Benzos do not feel the same, maybe an addiction to 1mg etizolam a day is equivalent to 10mg diaz if you are tapering, but apart from that the charts should not be taken as the gospel truth.

4mg is not the OD level either... I ate 10mg last night with no benzo tolerance and I slept well and feel fine.

you can only OD on benzos when mixing them with other drugs (unless you go OTT obviously...)

He could mean Estazolam?

 

[BabyGurl3171]

If it is Etizolam, 4 mg isn't OD level. I've taken up to 6 mgs but I HAVE TOLERANCE. As for you, it depends on what your tolerance level is for benzos. Plus some people don't get anything off benzos, just a relaxed, calm feelin.

 

[effie]

I presume you mean etizolam (1mg does = 10mg diaz) so I've changed it - let me know if you meant something else!

People's tolerance varies, even for the benzo-naive. It is actually quite hard to OD from benzos alone (although easy when mixed with another CNS depressant like alcohol or opioids) but you may well black out if you take too much, or injure yourself.. if you're not feeling much from 3mg then taking another 1mg is reasonable but make sure you give it a chance to kick in, and don't mix it with anything else..

Some people don't get much from any benzos, especially if you don't know what to expect. Others find that one benzo works well where as another doesn't. Etizolam is a thienobenzodiazepine but behaves like a normal benzo; it isn't hugely strong though and some people don't find it recreational at all (although I do )

 

[kokaino]

it is etizolam btw.

I find that all these benzo comparison charts are a bit stupid. Benzos do not feel the same, maybe an addiction to 1mg etizolam a day is equivalent to 10mg diaz if you are tapering, but apart from that the charts should not be taken as the gospel truth.

4mg is not the OD level either... I ate 10mg last night with no benzo tolerance and I slept well and feel fine.

you can only OD on benzos when mixing them with other drugs (unless you go OTT obviously...)

Not true, people have been known to OD on temazepam taken alone. French porno actress Karen Lancaume OD'd on temazepam alone. She committed suicide. NO alcohol, no other depressants, no nothing. Just temazepam.

Cases of nitrazepam, flunitrazepam, and flurazepam taken alone and causing death also exist.

 

[FlippingTop]

ODs from benzos are really quite hard to do. Unless you are trying to kill yourself, or an idiot, you are not going to die.

 

[effie]

^ very true, although temazepam is a bit different - it is quite a bit more toxic than others.

I presume etizolam is similar to the rest of the benzos but actually I don't know - it's a thienobenzodiazepine and I don't know much about it's toxicity..

 

[FlippingTop]

I was under the impression that the toxicity of a drug was not something that caused death, more lasting damage. Deaths from benzos would be caused by having your CNS depressed and eventually you stop breathing.
Is that not the case?

 

[kokaino]

There are studies that show a reduction in use of temazepam causes major reduction in benzodiazepine related overdose deaths - this study for example

This paper here claims that temazepam was a major cause of overdose deaths in the UK, particularly in Scotland.

And of course we've all seen the British studies on benzo toxicity, showing temazepam to have a much higher toxicity rating than other benzos. Temazepam's rating was so high, that it was higher than some tricyclic antidepressants and equal to a few barbiturates. That is pretty remarkable for a benzodiazepine.

A 1995 Australian study found that temazepam overdose is more likely to lead to coma than other benziodiazepines (again, corroborating the British studies). This is due to a high toxicity level that can be explained by the receptor affinity and absorption rates between benzodiazepines. The study found temazepam to have a more rapid absorption rate than other benzos, while oxazepam showed a slower absorption rate than other benzos - so it was least toxic.

 

[Tripman]

Not true, people have been known to OD on temazepam taken alone. French porno actress Karen Lancaume OD'd on temazepam alone. She committed suicide. NO alcohol, no other depressants, no nothing. Just temazepam.

Cases of nitrazepam, flunitrazepam, and flurazepam taken alone and causing death also exist.

I would like to see a toxicology report before I gave this a second thought.

The LD50 for any benzodiazepine on its own is simply out of reach unless you have access to a big pile of a pure Benzodiazepine powder...

 

[laCster]

i like etizolam, although it doesn't seem to pack the punch valium does... still better than xanax

 

[kokaino]

I would like to see a toxicology report before I gave this a second thought.

The LD50 for any benzodiazepine on its own is simply out of reach unless you have access to a big pile of a pure Benzodiazepine powder...

Here is a paper from the British Medical Journal. You'll notice there are two separate studies which corroborate each other. First is the Australian study (1995) which is highlighted in blue. Then as you scroll down, you will see it say "Introduction" and that is the beginning of the three year British study (1990-1993). Both studies showed temazepam to be far more toxic than other benzos.

Also, you can go HERE - it is "wikidoc" and it is detailed info on temazepam written by an actual doctor. You can click on the doctors name at the top and check out his picture and credentials. Just go to the "Toxicity" section of the page and read.

Or do you mean a toxicology report for the French porn star? It is well known that she committed suicide with temazepam. Check out any of her biographies and they will tell you the same. Plus, I have links to papers above in my other posts about the amount of overdose deaths temazepam had caused in Europe, especially the UK and Scotland in particular. In 1992, temazepam was totally banned in Sweden and Norway followed with a similar ban on the drug the year after due to the amount of deaths that were being attributed to the drug. You can also read this here to get an idea of just how many overdoses temazepam caused alone or in combination. And you also got this article. Temazepam was responsible for a huge number of overdoses, alone or taken in combination with other CNS depressants. Another article from Dr. Ashton's website here. All this and you want a "toxicology report" on a porn star who committed suicide using temazepam? Its in all her biographies and its not like she's the only one. Thousands and thousands have overdosed and died as a result of temazepam. Temazepam is different from other benzos as far as toxicity goes, as the study claims (the study claims that there are big differences between the benzos in terms of toxicity). Its toxicity rating is higher than some tricyclic antidepressants. That is remarkable, and deadly. So its a bit silly of you to ask for a "toxicology report" on 1 chic out of thousands and thousands.

Excerpt from Dr. Ashton:

Dr Oliver told BBC's Frontline Scotland programme last night: 'Approximately a third of all of last year's drug deaths involved Temazepam. And of the actual deaths themselves, at least 20 per cent had Temazepam as a very significant contributor to the cause of death.' Dr Oliver said he wanted to see Temazepam banned. He added: 'Heroin is still the biggest killer, but if we can eliminate the Temazepam-related deaths, we can reduce the number of drug deaths by 20 per cent.'

Excerpts from British study:

Of drugs frequently prescribed, temazepam had the highest number of deaths per million prescriptions at 11.9 (95% confidence interval 10.9 to 12.8 ); above that of some tricyclic antidepressants.3 4 In contrast, oxazepam had an index of 2.3 (1.2 to 3.4), and the index for all benzodiazepines combined was 5.7.

Oxazepam was less and temazepam was more sedating than other benzodiazepines with significance obtained for oxazepam in both the unadjusted and adjusted analyses (table II). (In the analysis of coma the odds ratios were adjusted for fewer variables as the others were not needed.)

The sedation produced by benzodiazepines in therapeutic doses and overdose has a poor correlation with measured drug concentration but is increased with rapid absorption.1 10 11 12 Temazepam is more rapidly absorbed and oxazepam is more slowly absorbed than most other benzodiazepines.

 

[Mr Blonde]

^ Interesting studies, thanks for the links! Around that time here in Australia, one highly abused form of temazepam was banned; gel caps, which were removed because people were injecting the liquid alongside heroin.

 

[kokaino]

^ Interesting studies, thanks for the links! Around that time here in Australia, one highly abused form of temazepam was banned; gel caps, which were removed because people were injecting the liquid alongside heroin.

Yes, I have read about it. Temazepam was also the major target in 85% of pharmacy robberies in Victoria and Queensland around that time. It was a big, big epidemic.

I have these to excerpts relating to Australia and temazepam:

The Australian Institute of Criminology conducts analysis on voluntarily provided urine samples from detainees at police watch houses at selected sites around Australia. In 2003, 24% of males and 40% of females tested positive for temazepam. As temazepam is available under prescription, however, the result does not necessarily translate to illegal use. Reflective of this, 24% of females and 12% of males reported they had taken prescription temazepam in the last fortnight while 31% of respondents reported using temazepam illegally in the previous thirty days

Temazepam based capsules and tablets are commonly detected by Customs at different ports and airports. Most are coming from countries where they are being illicitly manufactured in clandestine labs. Organized crime syndicates and drug barons in Eastern Europe and China are responsible for the illicit manufacture and distribution of temazepam. Clandestine "jellie labs" have been identified and shutdown in Russia, Ukraine, Greece, Czech Republic, Latvia and Belarus. Temazepam is also found occasionally in the baggage of air passengers. Customs detected 544 unauthorised importations of temazepam-based capsules in 2003–04. Most detections were of small or medium quantities of temazpeam (up to 200–300 tablets/capsules) brought to Australia for personal use. A number of importations, predominantly from China, involved quantities of over 1000 capsules. Most of the temazepam detected originated from the United Kingdom, Russia, China, France, and several Eastern Europe countries. The increase in illicit importation of temazepam in Australia to meet the high demands for the drug are likely due to two reasons: the fact that intravenous drug user-friendly temazepam capsules have been taken off the legal market, and because of a dramatic decrease in prescriptions for temazepam in Australia over the past five years. Customs detected 447 illicit importations of temazepam-based capsules in 2005–06, an increase from 341 in 2004–05, and a decrease from 544 detection in 2003–04. Quantities detected varied from 100 to 2,000 capsules per detection. Eastern European countries, China, Russia, India, United Kingdom, Sri Lanka, Philippines, Thailand, Singapore, New Zealand, Germany, France, South Africa, and even the United States, Peru, and Argentina. This is the first time that the US, Peru, Argentina, and Germany have been mentioned in Australian Illicit Drug Data Report (IDDR) for the importation of illicit temazepam. This may suggest a trend in the growth of an international temazepam epidemic. There were two detections of over 1,000 capsules—one from Sri Lanka and one from Peru—both of temazepam. Additionally, there were 12 detections of over 300 capsules and 10 detections of 100 to 300 capsules.

 

[Mr Blonde]

Wow, someone actually interested in Australia!

I like temazepam I suppose, but it's not very strong and you don't get many tablets in a bottle so whenever I had it I went through it in one or two doses.

 

[kokaino]

Wow, someone actually interested in Australia!

I like temazepam I suppose, but it's not very strong and you don't get many tablets in a bottle so whenever I had it I went through it in one or two doses.

That's the issue with temazepams. Like other strong hypnotics, tolerance skyrockets fast and mg for mg temazepam isn't exactly the most potent benzo out there.

But as far as side effects go, temazepam is a strong hypnotic, and according to the FDA, it is the only benzo with "euphoria" as a side effect.

I know in Australia it was either take temazepam gelcaps out, or put temazepam under Schedule 8.

 

[effie]

Thanks for the links kokaino

People were injecting the gel temazepams here in the UK too, with a high rate of complications. Temazepam is pretty much the only hypnotic benzo you can be prescribed however (tablets not gelcaps obviously) - nitrazepam at a push, very rarely flunitrazepam. I like it - I do find it is more euphoric than other benzos (etizolam comes close actually) but my tolerance isn't that high and I don't come across it often.

 

[Psychonauticunt]

I know that in this country, at least the following hypnotics are prescribed (or the following benzodiazepines also prescribed for sleep): brotizolam, midazolam, triazolam, diazepam, loprazolam, lorazepam, lormetazepam, oxazepam, temazepam, nitrazepam, flunitrazepam.

I have seen loprazolam, lormetazepam and flunitrazepam on friends, but never been even mentioned them by a doctor here. Brotizolam, midazolam and triazolam may have been mentioned had I not always said my problems were both to do with falling asleep and staying asleep (which they are). Lorazepam has been brought up, but the doctor was not very willing to prescribe it. I have been offered diazepam, oxazepam, temazepam and Z-drugs - and was recently told by a doctor that "the only drugs we really prescribe anymore for insomnia are zolpidem and temazepam". I'm on the 20mg gel caps now, but I suspect that when I tell them it's insufficient they may admit there are other alternatives - especially considering I can produce an old prescription for nitrazepam.

I found etizolam quite pleasant, but far from the most euphoric or overall agreeable in its effects. It was delightfully un-amnesic, though. I'm pretty sure it shares a similar safety profile with other benzodiazepines; ie. when not combined with other CNS depressants, you may have to eat hundreds of pills to OD.