Your List of Hallucinogens That Induce the Most Nausea/Discomfort

[bighouse911]

2c-e snorted made me feel like I would puke if i stood up for around 20 minutes but went away as I got used to it!

 

[frontbluntt]

I don't get any nausea whatsoever from 5-meo-xxx, granted I have only done 5-meo-mipt and 5-meo-dalt, and only once each. I didn't even know they made people nauseous.

However, 2c-e gives me unbearable discomfort and nausea, though I have never actually thrown up on it.

Alcohol makes me puke the entire next day if I get too drunk without hydrating a ton.

I tried MXE once and puked, though it might have been due to being slightly hungover when I took it and eating fast food that morning before I took it.

Opiates give me persistent nausea if I overdo them or eat on them, they give me nausea that literally NOTHING will ease besides laying perfectly still. This includes kratom.

 

[Solipsis]

IMO it's exaggerated that all the 5-MeO tryptamines would induce nausea but they do have a tendency to work on the body so maybe for other people a lot of them have that capacity. Though for me it is only 5-MeO-DiPT and that one was even tolerable, and yes if I come home tipsy and make the foolish mistake of eyeballing 5-MeO-DMT and snorting it then the result might very well be that it hits me like a freight train, I barf and lie on the floor wiped out at Jupiter gravity being steamrolled like an Italian pizza. 5-MeO-MiPT did a number on my physically but no nausea, and no vomitus.
Have not tried 5-MeO-DALT yet, the reports don't seem to indicate that it is unreasonably rough.

Yes 2C-E is a bad one IMO, but I think I already said that I believe that not the compound should be blamed but the way the user handles the body load. Often similar tips are given to try and work with it. Though if you are too late then you might not find yourself able to even stand up and channel that load. Even so, you can still meditate while lying down. If you feel victimized, or too lazy to work on it, or you haven't a clue how to meditate... ok. Maybe you're fucked. But I also believe your physical condition when starting is also paramount - having slept well and eaten well, not too greasy, not too little.

A number of times when I took codeine, I just wasn't feeling it very well and unhappy with the result took a bit more. This can give me some real body load from hell like I poisoned myself. Screw working with body energy like with psychedelics such as 2C-E. More like negotiating with your body to please forgive your poor judgement and clean up the toxic spill on isle 5.

The first time I took MXE, I also drank on it and took a really hefty dose of 2C-C. (Definitely not all at T+0:00 of course). I got more dizzy than any theme park ride ever made me, like someone put me in a washing machine only it made me feel dirty rather than clean. All this got me extremely disoriented and at some point I puked in the attic but did not see it coming. I felt like I screwed myself since I had no intention of explaining myself to family, it started to smell bad obviously, and my vision was like a total soup even without dumping my stomach. I had a hard time seeing what the hell I was doing but I got the job done.

I attribute the nausea to the vertigo though, and the vertigo to the presence of alcohol in the mix. It still made me laugh now and then in between, like when I lost my glasses and had to put in contact lenses with an insane amount of visuals, finding my glasses again (kind of close by), deciding I could take out my contacts again only to realize my glasses were lost again. And a few repetitions, reduced to a slapstick idiot. The hardest part was putting in the contacts with those visuals. I kept yelling: 'are you KIDDING ME WITH THIS??!! hahahaha'.
Good experiment, getting so lost in such a familiar place, but one time was enough.

 

[LogicSoDeveloped]

I have to say that for me it is probably Mushrooms followed by either 2c-e or 2c-i.

 

[PsychedelicPeptide]

I felt like high dose 2CE was a lot worse than anything high dose aMT ever did to me. I mostly get stomach churning from aMT but never really anything else added to it, except maybe one or two trips to the toilet early on- but I get that from just about everything. aMT is mild enough to where I am willing to do it again.

With 2CE I had stomach churning combined with a trip to the toilet at least a few per hour for a few hours. I couldn't believe it was happening. Like every 5 minutes I would get done, leave the bathroom, lay back down on the couch and a few minutes later it's back to the John... over and over and over. That night I remember I ate an entire bottle of rolaids! Well, at least I had a nice visual show looking at the magazines.

I only did high dose 2CE to cause the real bad problems one time that I remember well. I may have had another one or two bad experiences with it. But that was enough, I won't touch it anymore.

 

[Axed]

I get pretty nauseous from pretty much everything I take, from psychedelics to E to alcohol. It's usually on the come-up though, although there were times on 4-aco-dmt where I was in pain from being so nauseous. However, I've only actually puked while on DOC, and that happened twice. But after I was done vomiting, I felt so much better for the rest of the trip.

 

[Solipsis]

I wonder if there are endorphins released when you vomit or something like that, at least I guess it would send a signal that toxins have been disposed of.
Must be some mechanism behind the whole 'la purga'.

Also, regarding going to the toilet very frequently, I'm sure this is a common occurrence with mushrooms as well for a lot of people. But then it's also like you are not really sure whether you have to go or not or it can seem like it is leaking right through you, you can get the feeling like things are all wet when they really aren't. But I don't recall getting this with synthetic tryptamines and I don't know why that is. Coincidence? Nasty way of getting played or mindfucked if you ask me. Though it's better than real bedwetting when you chronically overdo it with K and G and maybe other downers. Fortunately that happened to me only a few times and got fixed when I took it down a notch or quit things. I also think it can happen to pretty much anyone who drinks way way too much on an occasion.

 

[Sepher]

aMT wins hands down, beating all of the 'traditional' psyches I've tried. Don't suffer hugely from the nausea usually attributed to it so much. It's more the constricted, tightness around my throat that I used to get coming on up on a decent E than it is a feeling that I'm genuinely about to puke, and it's usually passed by the time the peak hits. It does though absolutely rip through my guts unlike anything else.

A little general moistness in the arse area is to be expected on most psyches / stims, obviously, but we're talking bowl-spattering bum-gravy on aMT. We're talking shitting through the eye of the proverbial needle. And it hurts. Oh, how it hurts! We're talking soaking a dirty great wad of bog roll in cold water and clutching it desperately to a fiery ring-piece just to get some relief. Even pre-dosing on Loperamide only alleviates the worst of it, and it doesn't settle down. It's pretty much regular bathroom visits throughout the trip, and after, which is kind of ok seeing as the bathroom is the trippiest place in the house, but you can see too much of one in an evening.

 

[Winding Vines]

I wonder if there are endorphins released when you vomit or something like that, at least I guess it would send a signal that toxins have been disposed of.
Must be some mechanism behind the whole 'la purga'.

secondary dopamine, serotonin (5HT3), H1 Histamine, nicotinic (a la muscaric). Ohhh emesis