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cyprexa to abort lsd trip
- Thread starter badjaja
- Start date
Most likely. Wikipedia says that zyprexa (I'm assuming cyprexa is a typo) has a high binding affinity to 5HT-2A receptors, which is suspected to be the main receptor on which lsd acts. It is also regarded as an antipsychotic which have been used for years to abort trips.
clubberdude
Bluelighter
I'd imagine Zyprexa would be very damn effective at terminating just about any psychedelic... but the idea of using Zyprexa for this purpose sounds pretty heavy going - from what I can gather, Olanzapine is not the nicest of drugs. Would a benzodiazepine not be both safer and more pleasant?
Probably. Although if someone is inexperienced and tripping WAY too hard, a benzo would only reduce the anxiety factor and dampen the trip, as opposed to ending it all together (which is what the op is going for here I think.)
tmdoca
Bluelighter
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- Oct 6, 2011
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- 69
The OP has taken zyprexa before, I'm sure if they thought it was gonna be "not nice" to him, he wouldnt be asking this question.I can comment from my own use of the drug (Zyprexa) that the only negative side effect was that it made me a zombie (after the 3 days it took to take effect).
I wouldnt go suggesting that taking Zyprexa once is unhealthy OTHER than saying its smart to take a benzo at the same time, because Zyprexa lowers the seizure threshold.
tmdoca
Bluelighter
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- Oct 6, 2011
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- 69
Benzos are a good first line of defense should something go wrong, and im all for working through the problems that are presented to you on a trip, but the way I see it, benzos are just central nervous system depressants. Its gonna slow everything down, including the trip to some degree. This i believe is what you are experiencing, but i think this "level" you are describing is very shallow. Unless the benzo knocks you out (please dont take this much), your brain is still functioning and then therefore reacting to other drug in your system, LSD.
Antipsychotics like zyprexa, as indole said, bind to the receptor sites (both the 5ht2a and dopamine sites) that LSD agonizes. Zyprexa effectively plays goaly at the receptor sites that lsd is trying to score at. This feature, combined with the sedation caused by zyprexa (wikipedia says this is due to its action at histamine sites), makes zyprexa much more viable as a trip killer.
The catch is that when antipsychotics are used to treat actual mental disorders, it takes around 3 days to take effect. I dont know if this is the time it takes for the personality to catch up with the changes in neurochemistry (if this is the case taking zyprexa should kill a trip), or if 3 days is what it takes for levels to build up so that they are effective in changing the neurochemistry (if this is the case then antipsychotics shouldn't kill a trip). Seeing as there have been reports of antipsychotics working (including a report of my own), if say its safe to say the former option I suggested is corret.
PS if someone that actually knows something about neurochemistry could correct me I would be greatly pleased.
Alpralozam or Diazepam does kill VERY effectively 2C-X trips (not only relaxing you), can vouch for that. It (Alprazolam) does not kill LSD, and can have paradoxal effects at high doses like happened to a friend of mine, stick only to low to medium dosage. More info here. It's still very effective as first line of defense in psychedelic crisis, anti-psychotics should come after (see interactions 1st).