Alcohol withdrawal is a bitch -- DXM?

MagickalKat777

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Hey all,

I didn't know where else to post this.

I am a long time alcoholic. I have been drinking off and on since I was a kid (like 5 or so) and hit the bottle(s) hard when I turned 17. I hit 21 and I went crazy with it. 10-20 bottles of strong IPAs a day, rum, vodka, etc., until I passed out. I have had an up and down relationship with alcohol. It has been about as up and down as all of the personal relationships that I have had.

I don't drink much anymore because I am also on benzos (sometimes 2mg of Klonopin a day, sometimes 10-20mg of Valium a day - currently on Klonopin because I am out of Valium for all intents and purposes - I have 6 5mg V's left because someone stole my bottle of 10s and I can't find my V cut Valiums) and it seems like every time I drink even a little bit I end up in hell the next day. Paresthesia, tremor, palpitations, racing heart, panic attacks occasionally, the works.

What is causing this? I would think an occasional down-regulation and subsequent up-regulation of NMDA wouldn't be too extreme but every day after I drink I get all the symptoms. I feel like hell and sometimes when I drink I lose my shit - especially when I'm taking Klonopin (I really hate the stuff but it is either go without benzos which I've been on since 2004 - or go back on Klonopin which I have like a three month supply of from prior prescriptions that I didn't finish) - I've had some pretty serious mental health breakdowns when I've had too much of the bottle. I've actually learned not to do shots and just sip right off the bottle because of this. It keeps the episodes at bay.

Someone on the forum here (of course I can't find the post) mentioned that since both benzos and alcohol affect GABA, with alcohol binding to and destroying GABA, that the benzos may be "rattled off" of the GABA destroyed by alcohol use. This would explain the all-day benzo/alcohol withdrawal symptoms that I tend to have after using.

There is a post on DXM (Delsym form) for alcohol withdrawal but would a 20mg dose of Delsym be enough to knock NMDA down? I have two 5 ounce bottles of Delsym and the way that I am looking at it, I drank last night, its been about 6 hours since last drink, the withdrawals are starting and to avoid them what did I do? I took a swig off the whiskey bottle as soon as I got up. This isn't the way I want to live my life. It isn't fair that someone who has NEVER abused any of his benzos (I've been prescribed Xanax, Klonopin, and Valium - with the former and latter obviously being "recreational") to go through so much hell from a little bit of alcohol. Even more fucked up is that when I drink, the first few drinks actually make me anxious so I drink until I'm leveled out. Next thing you know I'm passed out drunk and waking up feeling like hell. I don't even get the "traditional" hangover. I don't get the headaches and sluggishness, I get symptoms of benzo/alcohol withdrawal and it sucks.

These are the things I have available to me right now and I could really use some advice - I have the Delsym, I have Vicodin, Vitamin E, trazodone, Valium, Klonopin, Celexa, and Wellbutrin. I'm half tempted to just dose myself up on 50-100mg of trazodone and sleep it off. Obviously I have plenty of alcohol readily accessible but that just furthers my problem. Also somewhere around here (god knows where) I have memantine.

I don't know what to do. These alcohol withdrawals though definitely make me want to kill myself and I'm not even depressed - I just don't want to deal with the consequences. I don't think its fair that people go on a rampage with benzos and alcohol and don't feel shit the next day even after doing it daily but I do it once a week or so and I get the shit kicked out of me. I only drank about 325mL of whiskey last night. To some that may seem like a lot but my bloodline is German and Irish. We can hold our liquor, benzos or not. =/ And alcoholism runs on BOTH sides of the family so I kind of got the short end of the stick on that one.

Is it all just in my head, playing into my latent GAD, panic disorder, and agoraphobia, or are there most likely other things going on?
 
lyrica or gabapentin works better than DXM for alcohol/benzo WD

DXM does work for opiate w/d's though
 
I've used DXM for benzo tapering before successfully but I feel alcohol withdrawal a LOT harder than benzo withdrawal probably because alcohol kicks in full blast within 6-12 hours and Valium has a ridiculous half life and Klonopin has quite a half life too. I've heard of memantine for alcohol withdrawal and I used it with benzos but DXM was more effective. I don't know what to do. I experience full-blown alcohol w/d every time I drink except it has never gone past the visual distortion and shaking point and I don't get sick to my stomach.
 
And I've used Lyrica before - unfortunately it doesn't do anything for me for any type of GABA-related w/d because of the fact that my GABA system is already so down-regulated from benzos. The benzos are more of a problem than the alcohol I guess you could say.
 
you might look into gabapentin...your initial post; I could have written, though towards the end I was drinking daily in addition to taking etizolam, phenibut and gabapentin, and tizanidine. i have belgian/english descent and both sides wrought with alcoholism.

Shits a bitch though, and I didn't see it coming because i would either alternate any one of the things i was taking with alcohol about 12+ beers daily and much more for occasions--the last being 12 beers and a fifth of brandy, along with phenibut and gabapentin tizanidine and [the unisom which actually put me to sleep]. Of course i can drink much more in a sitting, but that's not the point. My Gaba receptors had downregulated under the pressure of the immense torrent i was throwing at it. It caught me off guard because i wasn't drinking [relative to me] that much, but i had a pretty severe withdrawal, which is still continuing now.

The ativan spike i was given at the ER, I didn't even feel...I just noticed a minor drop in an tachycardia [down from 130 to 100, with normal hr around the high 40's]

i'm not recommending anything to fry your receptors, but you don't want anymore alcohol or 'hard' gabanergics to help with withdrawal. GBP can be mild, or even strong depending. the thing is that it has a really long duration which makes it kind of analagous to the principle behind methadone.

you could try phenibut too for w/d help, look it up, though the bitch of all this is that the w/d helper can cause dependence in and of itself.

I'm trying to taper with prescribed ativan, but have some gbp on the way which i will ask my doctor about.
I'm sick of withdrawal and really just want to be free from having to take anything postponing symptoms...but i raped my gaba receptors
 
you could try phenibut too for w/d help, look it up, though the bitch of all this is that the w/d helper can cause dependence in and of itself.

if someone is already addicted to alcohol and benzos adding an additional gabaergic is probaly a terrible idea.
 
Having been through withdraw from vodka many times and ended up in the ER as a result. I get bad WD bad... worse then other drugs. DT/ tremmor/ heart/ seeing hearing things/ depression/ cant sleep/ sweats/ shaking/ leg cramps/ body cramps/ and it goes on. I took val to get off of booze and now remain drug free. It took two weeks to detox and even with a high dose of VAL plus other drugs I remember the WD being HORRIBLE! the val didn't dent anything.. I don't know if it could of been worst but I feel benzos really don't help at all.

My best bet would be opiets. They always make my WD better no matter what im WD from so just take them and you will feel better. Try to ration them and just don't start back up learn from your mistakes. Take the vic and use the traz to sleep... you will make it save the benzos for after sense you need them. Once your booze WD over go back to your benzos. I say.
 
if someone is already addicted to alcohol and benzos adding an additional gabaergic is probaly a terrible idea.

right, all i want for anyone in my shoes is to be off anything, but quitting cold turkey on the gabaergic one-two [or four] punch is dangerous and will require some sort of taper...just offering suggestions here.

In the case of suggesting phenibut i would recommend switching rather than adding...which would definitely be a terrible idea vice-versa. Phenibut is a gabaergic, and one with a rather long duration...could help, but again i'm not a doctor
 
I just don't get why I withdraw after going weeks without drinking and having a relatively modest night of said drinking. I ended up drinking to fight off the withdrawals which I know I am going to pay double time for... Guess its 200mg of trazodone for me to get through tomorrow.

As for phenibut, that stuff has a much more rapid build of tolerance than benzos so what's the point? I have not tried GBP but I have tried Pregabalin (Lyrica) and even at 800mg, it didn't put a dent in my withdrawal. I hit 1200mg and then finally I was calm (high as hell actually when it hit me) but for about an hour and then I was even worse off than when I started (much like if I took alprazolam/Xanax). And at that level it is just simply too expensive. My doctor gave me 6 50mg trial bottles to see how I would do with it for tapering off of clonazepam/Klonopin. Obviously didn't work since he stuck me on diazepam/Valium. Now I ran out of that and I'm in a different state and I don't know what to do.

I have these Vicodins here but usually Vicodin MAKES me anxious being based off of thebaine instead of morphine. Too stimulating.

I just don't know what to do. I could always *QUIT* drinking but everyone says it like its so easy. Its in my blood and I've been drinking since I was pretty much a baby... Literally.

I have those Relax-All capsules by MRM Response Modifiers but it has phenibut in it and I'm afraid I'm just going to get hooked on the phenibut or worse, have a paradoxical reaction which I'm already prone to. I would try my chances with the DXM but I am afraid of the tachycardia and BP spike - if I have a panic attack and my panic meds aren't working then what the hell am I going to do? LOL. I hate GABAergic medication and I wish I never started them. Too late now though. I just need to get through tonight and tomorrow. Anyone ever tried trazodone? Its never failed to knock me out - I have mirtazapine in the car too but its known to lower the seizure threshold so I don't know that I want to mess with that since I'm sure between the benzos and alcohol my seizure threshold is anything but high right now.
 
Don't try to be a do-it-yourself molecular biologist and pharmacologist. Alcohol withdrawal is difficult enough. I would consider detoxing in a hospital.
 
it seems like every time I drink even a little bit I end up in hell the next day. Paresthesia, tremor, palpitations, racing heart, panic attacks occasionally, the works.

Careful. These can all be signs of pancreas issues. If you continue to drink, you increase your risk of developing pancreatic issues, which can be chronic and life-threatening.

I just don't get why I withdraw after going weeks without drinking and having a relatively modest night of said drinking.

This phenomenon is known as kindling and while the model is highly developed, not much is known about its epidemiology.
 
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