I can give at least some input here.
I'm autie, Kanner's phenotype (classic autism) (and if anybody is wondering, no I don't see autism as a disorder, just a very different CPU-architecture, so to speak. I'm very pro-spectrum really, as far as my outtake goes; to the point where I'd actually be quite devastated if, if I ever have kids, and they turned out not to be autistic. I only date other auties (although aspie ladies aren't off my menu either, or Rett's girls, but ideally any kids I'll ever have will turn out classically autie too, at least, I'd like that for them, I'd hate for them to miss out)
I've tripped plenty times on plenty different things, both tryptamines, psychedelic cathinones, psychedelic phenethylamines, lysergamides, as well as cannabinoids and dissociatives.
Whilst one thing I have noticed, is that without first developing a tolerance, my innate tolerance to many non-psychedelic psychotropics seems rather high, especially to GABAa agonists such as benzos, and the Z-drugs are nearly useless to me, the only exception being zolpidem, but that tends to make me react in a weird, trance-state inducing hallucinatory/dissociative sort of way.) Can take as much as 80-100mg nitrazepam, often even more before it will certainly put me out. Similarly, I require fairly large doses of opioids. Psychostimulants i seem very sensitive to, but at the same time, they don't really seem to have much compulsive nature to them, in me personally and I do not find these drugs addictive (stimulants)
With psychedelics, I respond to regular doses as one might expect the magnitude of the effect to be within a dose range. I don't find it in any way unusual in terms of my reactions to psychedelic drugs. I enjoy tripping, at least usually, with the usual provisos of set, setting etc.
And particularly, I find that it helps, (and ESPECIALLY when a light to medium psychedelic is paired with a cannabinoid) to bring back a sort of bright, fizzing sparklyness that I associate most with being a young kid, with eyes new to the world, and to being young at heart (albeit I confess, I am rather a cynic, but that is just something that came with age and seeing a lot of the nastier, darker and seedier aspects of the world and some of its inhabitants. Shit like that is bound to pollute the light in such a child-at-heart to some degree.)
But with a cannabinoid added to a psychedelic, it all comes right back, and I find myself doing things like going out to pick blackberries and wild plums, sea-buckthorn berries, japanese wineberries and other fruit that grows wild round here, and bounce my way merrily back home, with the world tingling at the edges, all throughout my perception, all the weight that comes with age and exposure to nasty, pollutant little sources of shit and effluent of the human, or at least, human-shaped variety, all that enthusiasm I had for the world as a 5yo eagerly delving into his mycology and botany textbooks, teaching himself to read, and then all those times I would go out hiking and find mushroom species, both poisonous, edible (and often quite delicious, better than anything the shops have to offer by far) or just interesting in their own right, for the first time etc.)
Its like...when I'm getting busy in my lab (autie speshul interest, science in general, but especially chemistry and the biological sciences, pharmacology, toxicology, as well as condensed matter physics), in a way, when I trip. All that joie de vivre, that sparkling tingle to the world comes rushing back, just as if I were busy conducting a vacuum distillation, separating out the fruits of my labours from byproducts, having success with an organic synthesis or a particularly exciting bit of inorganic chem, preparing reagents for my projects, carefully setting everything up, preparing the PCl3/PCl5, ICl, sulfur halides, acid chlorides or alkyl halides etc. and feeling the blood rush through my veins and my heart pumping hard in concentration and anticipation.)
Its like that, tripping, for me. In a way. Not QUITE like stimming, but the two do have things in common.
And maybe its also worth mentioning that I had my first ever trip, when I was relatively recently in secondary school (a speshul-ed school for classic auties), after going out and picking some liberty caps (Psilocybe semilanceata), drying them in preparation, so I could sneak them into school, hidden in a mint tin, after finding out we were to be taken on a long duration excursion of a couple of weeks, in a rural guest house retreat kinda place in the middle of yorkshire. Nice area, nice scenery, and at least as far as my time there ever went at any time I went there, it was also, barring one particular teacher who I always hated anyway [she really was an arrogant, gobby, opinionated, stuckup, selfish neurotypical curebie bitch with a chip on each shoulder, and both chips located somewhere around the middle of her intestinal canal, and she deserved to be despised, doing things like (and I caught her doing this, using a can of tomato juice that had mould growing all over the surface of the contents in a thick sheet of blue-black stinking soggy fur, and, to a low-functioning kid who had some mental retardation as well as being autistic, forcing him to scrape it off and use it anyway in food that he knew we would all have to eat after. SHE didn't eat any, no, did she hell, but she didn't give a damn about those worthless retarded spackers, it isn't like we'd ever amount to anything in life anyway so why should she bother (thats snark on my part, don't think for a moment that *I* would EVER view people with MR like that. Hell no. I've dated mentally challenged women, autistic women, autistic women who were mentally challenged, and really the only question is, if I'm to date, is WHICH, or what combination the other person will be. I treat people who are MR as equals, why? because they ARE equals.)
But otherwise, the place was shithead-less as you could ask for. And during a midnight feast that we (the kids) decided to get up late after bedtime for and have ourselves a party. Unbeknownst to all, I'd dropped the mint-tin full of libs a bit short of, maybe 3/4 hours beforehand, and started tripping, for the first time. One thing I actually noticed was that over the next weeks and months, with a quite rapid onset, was that my communication skills, particularly of the nonverbal kind well nigh skyrocketed, as if the mushrooms had catalyzed some sort of developmental changes that helped bring this subset of communication abilities out of their hidey-hole and whipped them into shape, had them standing to attention and saluting ship-fucking-shape.
It was such a huge change subjectively speaking, dramatic, and the onset and the way it unfurled as it all grew on, in, and through me that even at that age, i was well aware of it happening, and was most impressed and not a little shocked, especially at the speed the nonverbal and body-language communication capacity improved and refined itself.
I would very much wonder the results of a placebo-controlled double blind clinical trial series of psiloc(yb)in in autistic subjects, and in particular, child subjects with profound autism (that is what I call it, or refer to it as, profound autism/profoundly autistic, not the vile, perjorative, narrowminded term 'severe/severely' autistic, spoken by those with the mindset of seeing autism as a disease and auties, aspies all, as people who need to be made 'normal', which is disgustingly close to autism squea...ahem..SPEAKS...sorry, my bad...typo..honest it was
rabid curebie bitches and the repugnant faggotry they spew from their propaganda-mills. Because it IS profound, even in its 'mild' aspects, it is still a deep, rich and profound life experience, being autistic. Or at least it should be, when those who would make life difficult for us, other parties who would interfere that way, and act like shitheels who couldn't give a crap about, not even going out of their way to make thngs GOOD for us, but the ones who couldn't even give enough of a shit to refrain from making our lives more difficult, or in other ways unpleasant.
I'm classically, 'severely' in curebie-bilge, autistic. But *I* don't see it that way. Hell no. I'm proud of it. I'm comfortable with it, yes I take a few meds related to it, clonidine mostly, that helps me get away with less sensory static, and helps prevent me overloading, as well as now and then, on an as-needed basis, a benzo for sleep issues, since I've always had trouble sleeping, but no more than a couple of times a week, especially considering its likely to be 70mg+ of nitrazepam. Other than that, those particular aspects of it, as well as things like tactile sensitivities to certain textures, those I'd be glad to be rid of. But if it were to be at the price of being 'cured' and made into an NT then fuck no I wouldn't take it.
If it were just that, and otherwise changing nothing else, yeah I'd take something that just disposed of the inconveniences in a heartbeat, assuming no nasty side effects. But not at the expense of being 'cured'.
Why? because if you cure somebody autistic, if it were even possible, then you would be 'curing' a person of their soul, their spirit, their personality, everything at the core of what makes a human being a human being, and it would not be, IMO a cure, only killing the original inhabitant of the body, in order to hollow out an identical looking physical shell and install a new being in it.
Which is, if one looks at it with a certain angle, not that dissimilar to murder. The body isn't butchered, nobody gets shot. But the autistic person would be poisoned, and another being, with the memories and experiences of the autie/aspie/Rett's girl to access, read from, as if it were another computer being installed in the same housing,completely stripped down, and with all the important parts removed and replaced, with the memories and experiences loaded on a flash drive or ROM chip.
And what is near as can be to certain, is that big pharma wouldn't bother developing a cure for the 'cure'. Something to make people who were soul-murdered like that back into the autie or aspie they used to be, much less something that could turn a neurotypical autistic. Even if it were just for a short time. The best we can home for is that if there ever becomes available a genetic in-vitro test for autism, that it won't, as happened with down syndrome prenatal testing, be used to wipe us off the face of the earth (in case of Down syndrome, in many countries with regular prenatal testing used, the birth rate for live people with Down syndrome plummeted by 80 percent or even more. Why? because they were being aborted before they could ever have the chance to be born and live the lives that could have been theirs. I'd just hate to see a pogrom of that kind happen to us, too. Its a chilling thought, and a worry to many within the autie/aspie community and rightly so IMO)
Although of course there are those of the autistic community other than me, I am sure, who would use IVF to deliberately select for the autistic embryos and make sure that our kids turned out correctly.
Do tread with a light step with your autie friend, make sure to help make the environment one he is comfortable with and at home in, that he'll be happy in, and at ease. But don't get the idea that just because someone is spesh, that it means for some reason they shouldn't ever take psychedelics or other psychoactives. There is no contraindication, autism isn't like say, bipolar or schizophrenia or any form of psychosis or personality disorder. It is a profoundly different brain and psyche architecture. But think of it like say, running linux rather than windoze NT (see what I did there?
), with autism, rather than as with personality disorders or psychoses, which are more like hardware problems that cause the software to continually BSOD.
Its an important distinction to remember to make; that autism isn't a disease, or a disorder. Its a different way of being put together, and it doesn't mean there is anything wrong with us. So become one with the flappy side of the force, and viva le spazz
I do hope, if your autistic friend desires to try psychedelics, that you or he, or both, manage to find something for him that will work well, so he doesn't miss out.
And once the mechanics are sorted out, in respect of getting a psychedelic that he will respond to well, good ideas would be to have available (if he likes such things of course) sensory-tactile and sensory visual toys, things like rubber covered studded or spikey rollers, combs to run back and forth over the skin, or round brushes to step on and roll back and forth underneath the feet, favourite music, things like, if desirable for the subject, plasma globes, those volcano lamp things, as well as favourite foods and drinks, plus new food and drinks as yet untried, just in case he desires some novelty and to dip his feet into new waters. )
And make it a familiar environment, one that your friend loves, and feels safe in. with the proviso of course that he can always go out and choose a change of environment if, or when-ever he so desires. And if he indicates that he wants some time alone, (and tell him these things, make them all explicit, since auties, aspies can have difficulty reading implications, or reading 'between the lines', and also that if he at any times does want time alone, then it is his for as long as he needs, but that all he needs to do is to somehow indicate his need or desire for company again, that you will be within range, and if needs be, such as in case he goes nonverbal, then have something like a string threaded through some loops, into other rooms, that move something or trip an LED light to get your attention. The means to accomplish that end is up to you two, many ways to skin that sort of cat (pets being around if he has any loved animals would be another good idea, with of course, the proviso that his pets are not themselves dangerous, such as poisonous snakes, dangerous scorpions or spiders [some people do keep that sort of pet, I have. Have had black and brown widow spiders before], giant centipedes etc. that some pets just aren't the sort of creature one wants to have curl up at the foot of the bed as you drift off to sleep
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