This may gross you out but if you only have 100mg, the best route to take is anal, squirting a bit of water with MXE in it up your butthole, it greatly speeds the comeup and moreover, its almost twice as effective as oral use.
Me I use orally. Empty stomach, then swallow with half a glass of water, repeat after 1:30h
If you are doing oral anbd have a low tolerance I would recommend 33 + 33 + 33 with 2 1-1:30h intervals.
Most people with low tolerances find single high doses quite unpleasant, for most people 20-40mg is the perfect increment, allowing for a steep climb without too much tugging or shallow.
For me 30mg is perfect, even after 3 years of use, its high enough to be magical but not too overwhelming when it decides to hit HARD (sometimes it does!)
Oral MXE on the clock:
0min - gulp
5min onset
20min strong effects
40min shit gets real
1-2hour you emerge and think about boosting
3-4h a single dose ends
4-8h even if feeling sober a subsequent booster still stacks atop of the former
Its OK to eat bananas/fruit or drink milk or juice, those do not much interfere with oral MXE even when eaten/drank right after ingestion.
Dissolve your mxe ideally in a shotglass of lukewarm water.