Zohydro ER (hydrocodone bitartrate), created by Zogenix, which also makes needle-free sumatriptan injections, is to be released next month (March). They will be releasing this drug in 10, 15, 20, 30, 40, and 50 milligram CAPSULES, which I assume will be filled with a pure hydrocodone powder, despite the 11-2 panel of experts the FDA created to vote on the approval of the drug. This drug is now in production, obviously.
I was badly addicted to OxyContin for many years and I remain on buprenorphine to this day. This "new" drug, made from the same compound that first triggered my addiction to opioids (which I found in vicodin, of course) is to be released in EXACTLY the same way careless way that OXYCONTIN was released by Purdue Pharma except in a presumably even more abusable form, a powder within a capsule. Zogenix and Zohydro's proponents have even gone so far as to reject claims that the new Tylenol-free formulation should be required to have a similar abuse preventative formulation that Purdue Pharma was finally forced into creating so as to continue selling their pure-formulation OxyCodone which is now, of course, the new, very unsexy OP.
Ah, now down to business. This drug is making my scrotum stir with anticipation; I cannot see a future where Zohydro exists where I also do not get high on it. What the fuck do you guys think about this new thing? Could this be the gnarliest opiate "epidemic" since, well, morphine? I want thoughts, information, experience, opinion, conjecture or speculation any of you professionals have on this new drug.
In my opinion, this is going to change history.
(FYI, this thread was moved from Other Drugs)
I doubt they are pure hydrocodone powder in there, probably more like classic time release beads in HydromorphContins here and also in multiple ER morphine pills (Kadians, M-Eslons). I think if they get any popularity, they will reach HydromorphContin levels, and it's not as bad, since most junkie worth its monicker knows that snorting and shooting up hydrocodone is stupid/dangerous ( I did it with our pure Hycodan 5mg pills here, just 2 of them, and it didn't do much and I was pretty damn itchy all night, nevermind the 100mg hydroxyzine I took with it.) So yeah, this is an even smarter product than HydromorphContins (to be supplied as a first line opiate painkiller when NSAIDs and tylenol aren't doing it). It's amazing how hydromorphone is thrown at us in Canada, wheter in regular Dilaudid form or HydromorphContins (which can be banged, easily, more people are on methadone and bupe than for HydromorphContins IV habits than Heroin habits here). And we do not hear about how those pills are evil in capsules at all here. Most people fear official medication and are more than ready to eat and snort typical canadian meth pills when it comes to hard street drugs.
Through obscurity, painkiller addiction remains very low in Canada, even with how liberally they are scripted, people who are scripted them long term are never abandoned. The most known opiate painkiller pills are Empracet 30's (tylenol 300mg/30mg codeine), there's 60's too but they're really rare. This is from studying in the academic way and from experience in my own pretty large circle of drug users before I dropped out of the scene.
I discovered how awesome IV'ing Dilaudid was after breaking up with a long time girlfriend. All the people saying "IV dilaudid or nothing" are to blame I tell ya!
Just kidding, my dentist who was scripting me 90 counts of 1mg Dilaudids had me addicted once I started snorting them, 2mgs a bit later then I made friends with an ex boxer who was scripted both HydromorphContins and Dilaudids and there ya go.
I don't see american media going mad about Dilaudid, a much, much more hazardous substance than hydrocodone...Who profits from railing against a medication that is approved anyway, massively. I heard Massachussets banned ZoHydro. Mitt Romneycare doesn't only seem to suck, it's also idiotic. Yeah don't script a 30mg ZoHydro to this person! Here you go! *patient leaves with 30mg OXY IR's or 60mg MS-Contins or whatever else....the stupid, it hurts.
I forgot, were CodeineContins ever considered in the US? Because Purdue has also successfully pushed this one in. They make much more sense than going for stronger painkillers too, like ZoHydro (hydrocodone being marginally stronger than codeine, IN EFFECTS/stimulation of opiate receptors). We got C Contins 50mg,100,150,200. They are one major reason why tramadol was never really popular here, it only managed to come in as Tramacet 37,5mg/325mg tylenol. Last year they approved Zytram XL, time released tramadol and it is still almost totally unheard of, like Tramacet. They only consider it according to my nurse female friend when people are allergic to codeine/morphine, and they go with Demerol. I once asked an ER doctor if I could have Tramadol (around 2007) since it's a good painkiller thats apparently non addictive and she went like "sure, but don't you mean Tramacet? They have tylenol in them does that bother you?" And I passed and said what are my options here ? And I left with 20 Empracets 60's and 30 CodeineContins 200mg. Those can be made IR just by crushing them, like our generic oxycontins.
All of this to say that codeine is an overlooked product, and the higher dosages which were normally shunt, were embraced as XR pills. But I hear that in America people say codeine = morphine, even health professionals spout bullshit like this apparently and go straight to hydrocodone/oxycodone. Like oral oxy is less dangerous than oral morphine. To get high on oral morphine you need massive dosages, even if quite opiate naive, I managed to do it by eating 130mg Kadians where I crushed the bead to turn them IR and eat em after some large Tagamet dose, 600mg or something or eating multiple generic 60mg MS-Contins (the purple ones). And lets not get into the actual usefulness of HydromorphContins used orally. The boxer guy who got me into them was eating them....but he was scripted the highest strength pills (30mg) 4 times a day + 8 x 4mg dilaudid. So, yeah, I know you guys don't have HydromorphContins, you had them as Palladone XR or something for 6 months a decade+ ago and they FDA removed it due to dose dumping caused by drinking just one beer over your high dosage HMC pills (9mg+ I guess). I tried the thing with 12mg HMC's...nope, this wasn't an issue. They just outright lied to you guys because they expected what Purdue was doing, what us canadians are plagued by IV HydromorphContin crushed beads addicts. Imagine the bang for the buck a 30mg HMC pill offers to a Dilaudid fiend like me...
No wonder this world is going to hell, Orwell everywhere.
