sorry for bumping an old thread but my .02c (AUD so worth less):
I get IV ket infusions twice a year for chronic pain. I'm on the drip for a week at a time as an inpatient, between 20-24mg/hr depending on my body weight at the time (I am very skinny), I think that's about the equivalent of 50-60mg intranasal. Not a hole dose obvs but you are very much off baseline for a *long* time. +/++ for a week straight - it gets stronger at night and meditation can take me some weird and wonderful infinite spaces, CEVs, insane dreams the one time I had temazepam . Anyway. It is SO HARD to sleep on the drip - the first time I had t I actually had a nervous breakdown by day 5/6 because I'd barely slept so in combination with the dissociative effect and the sensory overload nightmare that is a hospital room without a door i was losing my mind. For admissions after that i got charted for a decent amount of valium, 10mg 3 times daily. While on it I can't have any caffeine or cannabis - yes they let you have it as an inpatient if it's been prescribed! - because it just sends my body into overdrive, even with valium. Heartrate and blood pressure will both increase along with significant anxiety.
I also get charted for, but have not yet used, low dose haloperidol 0.5mg, which I was told for anxiety caused by the dissociative/psychedelic effects of the ket. I thought perhaps that might have been the same overkill school of thought that has docs prescribing seroquel for anxiety but reading this thread seems like it is in fact specifically targeted to block the dopaminergic effects thereby reducing the psychedelia but also the stimulation. Interesting. Perhaps I might try it on the next infusion in October as insomnia is already kicking my ass in my nice controlled home environment.
PS What effect might the haloperidol have on my body temperature? I have a tendency to feel quite hot on the drip - my body temp will stay raised .5-.7C above my norm which isn't a danger but is quite shit for sleep as well.
