I never had a full on deliriant trip yet but i always wondered how people could see real OEVs because, as far as i know, we don't have an exact photographic memory, do we ? Or maybe anticholinergics (among loads of drugs) exploit more of the brain's potential, in comparison with the limited sober state of consciousness.
Dude, from what i read you need like 700 mgs of DPH to induce the delirium (drugs.com, erowid). You managed to hallucinate on 200-300 mgs? A few days ago i did (first timer) 300 mgs DPH + ganja only to induce sedative effects... then i tried redosing it to 500 mgs but it wasn't enough and it made me fall asleep....
Saaaame here, this has me confused. But what's really weird is that although I've experienced very mild delerium on DPH in the past, all my latest doses have simply felt like a mild, short lasting version of amphetamine (the primary effect being becoming horny and getting penis shrinkage). That's very weird considering in the past I've gotten deleriant and drowsy effects.
In any case, here's some literature that supports the amphetamine effect:
The tropane alkaloids, especially hyoscine (scopolamine) (18), have been used to treat PD since they increase DA activity by antagonizing cholinergic activity at the muscarinic receptors in the striatum. The naturally occurring alkaloids, found in various genera of the Solanaceae, are not used much for this purpose but synthetic analogues e.g. benzatropine (19) are used since they also inhibit DA reuptake, and the resultant increase in DA compensates for the deficiency of DA associated with [Parkinson's Disease].
Selected Topics in the Chemistry of Natural Products (Raphael Ikan, 2008), p. 406
Note: amphetamine is a dopamine releaser.
FYI, diphenhydramine has a connection with Solanaceous chemicals:
Following the description of the structure and activity of scoplamine by Ladenburg, the search for synthetic analogues of and methods for total synthesis of scoplamine and/or atropine in the 1930s and 1940s resulted in the discovery of diphenhydramine, an early antihistamine and the prototype of its chemical subclass of these drugs, and pethidine, the first fully synthetic opioid analgesic, known as Dolatin and Demerol amongst many other trade names.
Pharmacology for Anesthetists 5, John D. Current, M.D., p. 195
I also want to add that the amphetamine effect I experienced included a feeling of being burnt out on the come down, just like amphetamine does. And a worsening of this crash when dosing more to try to feel better (including feeling like I had a fever). Furthermore, something scary happened to me: I fell while walking and experiencing the rebound effects and when I hit the ground I quickly became extremely dizzy, so much so that I thought I was going to wind up in the back of an ambulence, breathing in and out, hanging onto my life. Luckily I immediately went back to normal though....
I also messed with low-moderate doses of datura seeds many times recently and never got the same level of amphetamine effect that DPH produced, although it was there to an extent. On the positive side, datura never made me crash the way DPH did. Datura
always produced a delerium-type effect, which was suspiciously absent from some of my DPH trials. And note that I've never experienced the full blow delerium that these substances are notorious for.
I would describe this 'delerium effect' as downright stupid. Memory impairment is also an effect, so you won't even remember much. Using datura in combination with like 4 mg of Klonopin on one occasion resulted in a complete black out. I found myself sitting on the steps of a building with no memory of how I got there. Even later I found that I had lost my sneakers and I have no memory of how that happened, although I remember that I was putting my shoes back on before being asked to leave the steps of the building, so I was obviously taking my shoes off.
I had quite a nice trip all told, no spiders or creepiness, had a conversation with a pigeon like it was normal, had a run through different people I knew standing at the foot of my bed, right up until I went to talk to them and I had a flash of sobriety and realised they weren't real. No spiders, the sore throat was the worst bit for me, oh and trying to plug my laptop in, only to realise my laptop wasn't there, that got annoying.
Yeah, I've had a small taste of what you're describing. I've never seen something as dramatic as a person standing at the foot of my bed, but here's an example of what I've experienced: I was sitting at the counter in my kitchen and my mom was sweeping. When not looking at her, I slipped into a state where she wasn't my mom but rather the cleaning lady and I asked her, 'is my mom coming back soon?' She said, 'I am your mother' and I looked up and snapped out of it and it was like 'whoa, you're really fucked up.' I had already told her that I was experimenting with it for antidepressant reasons. She ended up calling the police on me when it became apparent how fucked up I was and I had to spend hours in the hospital until it wore off. But one thing I wanna emphasize is that one does not just see things like people who aren't there, rather one slips into a dream-like state in which such things can occur, right?