A lot of people here seem to be equating temporary cognitive impairments with brain damage.
They're not the same thing. "Brain damage" means actual structural damage, which by definition is irreversible (neurons are the only cells in the body that don't regenerate).
From what I've read, alcohol, mephendrone and amphetamines all do clear and pretty easily observed damage to various brain structures. Mephedrone is reputed to cause permanent damage faster than any other drug, but who knows if that's actually true.
With other drugs, it's just harder to say.
The effects I get off ecstasy always seem to be telling me that what's going on in my brain just CAN'T be good, but apparently the jury's out on whether the effects are permanent. That said, E is sort of like pot in that people who really like it seem to get all emotionally invested in proving that it's a totally healthy and therapeutic and every person and their dog needs to try it at least once and blah blah blah, so you never know how much of the "no proven permanent damage" research is just e-tards with biochem degrees trying to justify their own actions. Like I find the erowid MDMA vault has this noticeable pro-E slant, and goes out of its way to play up the fact that some psychoanalysts found it useful in their sessions and shit like that.
They're not the same thing. "Brain damage" means actual structural damage, which by definition is irreversible (neurons are the only cells in the body that don't regenerate).
From what I've read, alcohol, mephendrone and amphetamines all do clear and pretty easily observed damage to various brain structures. Mephedrone is reputed to cause permanent damage faster than any other drug, but who knows if that's actually true.
With other drugs, it's just harder to say.
The effects I get off ecstasy always seem to be telling me that what's going on in my brain just CAN'T be good, but apparently the jury's out on whether the effects are permanent. That said, E is sort of like pot in that people who really like it seem to get all emotionally invested in proving that it's a totally healthy and therapeutic and every person and their dog needs to try it at least once and blah blah blah, so you never know how much of the "no proven permanent damage" research is just e-tards with biochem degrees trying to justify their own actions. Like I find the erowid MDMA vault has this noticeable pro-E slant, and goes out of its way to play up the fact that some psychoanalysts found it useful in their sessions and shit like that.