NBOMes aren't nauseating for me, unlike most substances. Though if I take them orally instead of buccally, I will feel a little unsettled and have to take a dump or three during the come-up. But it's nowhere near as bad as most other things I've tried.
The worst gut-wrenching nausea I've ever gotten is from some 4-AcO-DMT which had turned gray and clumpy in the vial it was in, and I had kind of an existential crisis while experiencing it, wondering things like, why must I exist as a biological creature, and how much pain is it possible to experience before I will go insane? But even then I didn't throw up, though I very much wanted to at the time.