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  • BDD Moderators: Keif’ Richards | negrogesic

What is happening??? Hopefully someone out there can help.

sb_33

Greenlighter
Joined
Oct 6, 2016
Messages
44
Ok, i would say that this is probably the main reason that i decided to stop lurking and finally make a BL account, because what im experiencing is beyond frustrating. Hope this is the right section, as its part basic-preventative info, part trip report(s), part pharmacology... idk. I thank each and every person who reads thru this, as i am seriously having difficulty figuring this out and i know SOMEONE out there has experienced something similar.

A little background... im 27 y/o, male, live in southern California. Been using one drug or another for 10 years, opiates basically throughout until 3 months ago. I would say that i am definitely an authority on drugs and how they affect MY body and what i can expect out of one drug or another.

I have dabbled in just about every drug there is, save for real mescaline and PCP (just never came across my path i guess LOL) but, as most of us know, the one that really undeniably sunk its teeth in was the general brand of opiates...painkillers, predominantly heroin. Ive had it in my life for 7 years and could not for the life of me kick it for more time than i was in residential treatment. Typical story, i know. In the last treatment i was in, one of the staff members told me about a once a month shot called Vivitrol. She said it blocked all effects from opiates and was proven to significantly curb cravings. Sounded good, and my insurance would cover it in its entirety. ($1200/ shot otherwise)

I decided to give it a go. They told me in the consultation that i needed to be 7-10 days clean prior to getting the shot, as precipitated (acute, accelerated) w/d would happen if i didnt, since Vivitrol immediately knock any opioids right off your receptors and sits on them for the duration, not allowing any other chems to attach. I was not able to gather enough willpower to stop even for ONE day, and used all the way up until the night before, telling myself i would be able to handle a day or two of kicking, if it meant freedom from dope afterwards. I got the shot and within 30 minutes, already felt sore, yawning like crazy, and my legs were starting on their trip as well. All symptoms just got worse and i had a fairly terrible rest of the day, night and morning after. And then it was over, i felt ok.

I have not had ANY cravings at all to use opiates, or even TRY and see if it would work, as many ppl on here have (to no avail). I knew that it would be a waste of cash and total frustration, and plus, i didnt feel like i needed it at ALL. The absence of opiate cravings still stands true to this day.

My problem is... I have tried other drugs (since i still feel like getting high from time to time) and have noticed something (actually a few something's) that the doctor or the internet never told me was going to happen. My sex drive is all but completely left me. I dont ever get even a dirty thought around the sexy girls at my work, feel the urge to masturbate or watch porn at all, and cant even get hard when said porn is watched. Drinking is also out, alcohol has no pleasurable effects but i knew that goin in. Not much of a big drinker, dont mind. I dont eat or crave food like i used to, nor do i sleep quite as well.

AND THE KICKER... i have done meth, powder cocaine, even smoked rock cocaine (just to see if itd work!!) and realized that the effects of these drugs (which act primarily by releasing more dopamine, more or less) have been greatly diminished or straight up ERASED by... something.. Vivitrol is seemingly the variable, but i also started taking a slew of vitamins (lsted at bottom) in the last 2 months, which corresponds with the loss of effects. Im sayin i can smoke a bunch of crystal, til im basically shakin, and not feel one single ioda of desire to watch porn..or do much of anything for that matter. Sex ruled my mind when i used to do meth here and there, and EVERYTHING was super fun. Now granted i have been smoking it fairly consistently for about the last month, and take tolerance/ dopamine reuptake pathway damage into account. But especially since after the 3rd shot, the effects of any stim have been SIGNIFICANTLY reduced. Since this started noticeably occurring, i have researched a bit and seen some studies for Naltrexone (Vivitrol) suggesting that it can help with more than just opiates & alcohol... but meth as well, as proven by people coming in and being given Naltrexone (or placebo) for a few days and then given IV methamphetamine. Naltrexone works by, essentially, blocking the dopamine reuptake/release via an outside agonist (heroin), and in my experience, does not affect dopamine release from natural stimuli, like actually having fun, good music, etc. However, heroin, meth, coke, amp, and many other drugs work on the dopamine receptors, thus presenting the possibility of some (or all) of their effects being somewhat muted. Like off-label uses that havent been thoroughly discovered yet.

Now, I have taken these stims (meth, coke) before starting Viv and can attest to their quality, as I lived 2-3 hrs from the border and the coke and crys that i always get are both from the same...well... the same guy with Mexican cartel connections... just know its quality, respectively the best ive had of both.

So know i am seemingly OUT of options, except to be sober, which i mean... isnt so bad, but id still like to use occasionally since nothing but opiates have been detrimantal in my life thus far and ive never liked anything else enough to do it consistently at all. I dont like weed, after i stopped smoking years ago, it just makes me way too high and uncomfortable every time i do it. Its out. Psychs are fun, acid works just fine LOL did it a few weeks back, but psychs dont fit the bill of what im lookin for in terms of social/ comfortable use, understandably.

Now i know some of you will probably just say somethin like "count your blessings and be clean, most of us would Love to be free of real cravings and out from under the fear of w/d!!!"

I get it. Im just looking for some people who have experienced something like this, AS WELL AS PEOPLE THAT THINK IM TOTALLY WRONG!! please. i WANT to be wrong, but i know its not weak dope. I dont ever smoke coke, EVER. and i did earlier today (HUGE rips, should have been major ringers, but instead had no high OR any comedown). I want to think a period of abstinence from everything is all i need, maybe a few weeks, but ive never needed that before to get high...

. Im currently on the 3rd month of Vivitrol (Naltrexone) 350mg time release injection as well as these supplements DAILY:

-GNC Mens multivitamin (plenty of random ingredients)
-1000mg Omega 3 fish oil
-500-1000mg L-tyrosine (for dopamine supplementation...tell me if youve heard it can be an inhibitor!!)
-100mg 5-htp (for serotonin supplementation..again.......^^^)
-500mg Turmeric root extract (great antioxidant, many uses)

Thank you so much for reading this and pleasee leave me any input you think is necessary..or not necessary, i dont care.
 
I'm on my way out the door to the classroom as I'm typing this, but I hear you OP. When I get off later on today I'll be able to actually read the entirety of your post and hopefully give you some decent answers. I just don't have time now sadly :(. I just wanted you to know you're not being ignored!
 
Hey Sb, I just read through your post. I'm just trying to figure out what your main issue is? You've got a lot of text going on here and a lot of different points made, raning from the lack of sex drive to the desire to use other drugs and so on. Could you maybe just condense it a little bit? I haven't personally had the Naltrexone shot before, but I know of several people who have had it.

So yea, just get back to us with some of your main gripes in a more succint form. You'll probably get more answers from the community at large by doing this as well!
 
Wow, $1200 for this shot? Oh man! I couldn't force myself to do that! Especially after reading some of the side effects you are getting! That doesn't sound like fun to me! I am going to do some research online later, i have been hearing about this drug, my mom actually told me i should get it rather than take bupe everyday, to save money in the long run... but i take other meds too, like benzos and amps... don't need that vivitrol fucking with my other meds, just to get off bupe.. i think i will keep the bupe! I am sorry it hasn't worked out as well as it was supposed to for you, hang in there.. i wouldn't take another shot of it, if i were you though! I mean that sounds like hell to me, not able to get a woody or let loose!??! hellll no! or smoke crack and get anything from it?! no fucking possible way, i would ever willingly take that shot! i am sure that's not what you signed up for, and probably just wanted your opiate cravings to go away! i would be fucking livid! Very informative post, and thank you for sharing! I hope these side effects you are experiencing subside for you soon! Good luck!
 
is your post a question or a general warning? i'm kind of confused but either way it sounds horrible :(
but i suppose to get to the point of having one of these shots opiates must have impacted your life significantly - i hope you dont get into a similar situation when the Viv. eventually wears off
hope you're well
 
Wait, wo....are you saying you no longer have a sex drive?? If that's what you're saying, or even part of what you're saying, I really want to hear more or hear input on this. Does that happen? Do narcotics kill sex drive?!?!?
 
Thanks for the replies, guys.

The MAIN point of my ridiculous OP was to see if anyone here has any experience or knowledge with regard to contraindications between Naltrexone and coke/meth/molly or stated supplements ( at bottom of page) and coke/meth/molly.

I have to say, i am NOT totally upset, as this situation is proving to be somewhat up-and -down, as i expected it may be at some point. I am not pissed as i go through each day and want to reiterate that however my initial post came off last night, there definitely ARE positives to the shot. After i typed the OP out last night, i smoked up the rest of my crystal and, just like some random other times, got realll high off just like 4-5 hits. PLUS, i felt the strong urge to watch some fuckin porn (FINALLY) for the first time in about a month and enjoyed a glorious hour or so of much needed j3rkin. =D

Keif, my main gripes go like this. On a pretty damn consistent basis, i dont think about sex, nor does M-Amp intensify said feelings at all... although im realizing that with crystal, the highs (as a whole, all effects) can never be predetermined and CAN still hit pretty hard. (i plugged m-amp earlier today after reading about how dominant it is over smoking, since i wont shoot.) I plugged a .8 in two servings, a few hours apart, so much cleaner than smoking. so much. Also, as evidenced by studies done that are easily found w/ a google search, cocaine's effects are basically muted altogether. Like i said... powder... rock...(i smoked about 6-7 monster hits last night, holding them in for as long as possible. NOTHING but a numb mouth and a little energy. So those are my issues... i want to use stims to their full potential and be able to have sex WHEN i WANT. I feel like im bitching, but then again i just posted this to get input.. after all, these are things that most people dont have to be deprived of... so i dont want to be..

iLove2Nod, i need to continue taking the shot each month as long as im living at my parents, which... with my other expenses, is a necessity right now... possible move down the road. and if it was $1200 per shot, i would never have gotten it. Anthem Blue Cross Insurance covers the entire cost... at least for now. Having a bit of an issue with this months coverage, due to my income.. so we'll see.

Keeping... i hear ya, im honestly scared of the prospect of stopping, because as of this moment, i could not FATHOM going back to dope. there is NO WAY i could do it. But i also know that i gave myself and made up every reason and justification to get a sack in the past, over all else. BROKE my family. I cant go back. none of the other drugs mentioned have ever gripped me like opes... im actually able to say (w/ crystal, coke, molly, etc) "eh, its getting late... imma go home and sleep" without too much difficulty.
 
Well, I don't have experience with vivitrol. But I do have 20+ years of heroin/opiate/methadone maintenance experience

What you describe as far as sex drive happens to many people on opiates. I know for me on methadone maintenance it was the same. Very rarely if ever had sexual thoughts/drives. (Although I can attest to the fact that cocaine works just fine on methadone, I ended up on quite the binge one year as I wanted to get high and the opiates were pretty much blocked)

Even on heroin many people also experience the lack of sex drive. Ask most heroin addicts and they will tell you sex is low on the list of desires so to speak,...many have issues with significant others who don't understand it....

From a purely theoretical standpoint it's interesting that all the other drugs have no effect...I have only experienced something similar after a 5 day cocaine shooting binge. I could do a shot and .....nothing. I had literally drained the dopamine in my system and could experience nothing from a huge shot. Like I would feel the very beginning start to go up....and stop. I needed sleep to replenish my system. Not that sleep will help your issue, just saying what helped me.

Honestly though, if you're doing methamphetamine on a daily basis for weeks as you mentioned, you could be experiencing issues due to that.
And don't take this the wrong way, but, if you're at the point at 27 you're back at your parents maybe it's a blessing in disguise and a good reason to take a break and get yourself a bit together. Not judging. Been there and worse; as I get older though I realize it's good to take breaks....can't run yourself into the ground like you're 22. No one wants to be the homeless junkie at 50....;)


I would say take a month off everything. Then if you are so inclined try meth or coke and see what happens ....

Anyway , at least the shot is allowing you a chance to break free of the opiate chains. And sorry I can't specifically help with the vivitrol. That wasn't even used when I was at my worst and in a position where I probably would've been made to take it. But sounds overall like you have benefitted. :)
 
Thanks crzy, i have been thinkin the same thing. Month off everything would surely give me the answers i am looking for in all the wrong places.

Just to touch on this since you mentioned it, in my years of daily heroin and oxy use, i never experienced any lack of sex drive, as a matter of fact i was like a rabid dog with my girlfriend every single night, especially after we moved in together.... Ah tha good times.. lol.... But if you just google search naltrexone decreasing libido Or sex drive, somethin like that, many people treat it like its an automatic for this med. For me with the time-release shot version, i didnt experience any change in sexual desire or libido until after i got my second shot (LOL it was still 10pm-7am wank seshes every night i was high). Couldnt be further from that now.

I somewhat gave up on smoking it (meth), wont bang it, dont like railing it... so i read about plugging it a few days back and have been doing that since. I Can easily handle a full G without having any negative effects, while getting moderate euphoria and my whole body feeling like a million bucks for a few hours..And thats after PLUGGING A WHOLE GRAM.... the effects are just about as intense if not less than when i started this episode a few months back, just from smoking 5 or 6 hits. I really think that it's, more than anything, an issue of tolerance. ANd the reason i say that is bc when i started smoking here and there after starting the shot almost 3 months ago, i definitely was LIT like NO OTHER. If i had ingested the amount of drugs back then with that tolerance (and mind you this is in a time RIGHT after getting a Vivitrol shot), i would have been off the wall.

Even on the Vivitrol, there was a time not too long ago when i would go over and smoke some... and literally... i felt it was the best course of action to actually get completely naked WHILE driving on the freeway at 80mph and proceeded to drive the remainder of the way home like that. I felt ON top OF THE W-O-R-L-D every time i smoked for about... a week or so. Then just started needing more and more.

At any rate, your message is clear and i just need to man up and do whats best... cuz right now im just beatin a dead horse and i know it. I keep thinkin if i change ROA, itll work. Nah. Need sleep, food and time.

------------------
And to you, my buddy the ShardHunter,

No, i do not believe that by and large, narcotics (as in ANY sort of recreational drugs) have a substantial negative effect on sexual behaviors and desires, most definitely it AMPLIFIES THE FUCK out of the sex drive, especially but not limited to MDMA, coke (hard to get hard though, IME), meth (<-----THIS).

When i was using heroin daily i was living with a girlfriend, we fucked like nobodys business, so...no issue there. I could never get up on coke though... and sometimes with mdma.

I think the point that you are honing in on is this.. Narcotics do NOT kill your sex drive, but in My experience, Vivitrol (ESPECIALLY after the 2nd shot and since then) has made my sex drive virtually disappear. I use crystal now more often, and not once through the entire night will i watch porn or touch myself... and that used to be the ONLY thing i did. for 8-10 hrs strong. Hope that addresses your concerns.
 
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Yeah, truthfully I never experienced the lack of sex drive on heroin either. It actually would make me horny. Methadone on the other hand really did kill sex drive. And for a lot of people, any opiate kills the sex drive...
Cocaine for me (when IV) made me not want anyone to touch me...different though with different ROA


I haven't done meth since the 90s when it was called crank...but what I took away from those experiences was that it was not a good daily use drug. It was much more effective used with couple day breaks in between. I think it's the same reason as when I've shot coke too many days straight...the dopamine gets drained

Anyway yes I think your best bet is at least a few weeks off everything then reevaluate with clarity and a healthy dopamine supply lol
 
If your main point, OP, was about your ability to get high on recreational drugs while on the Monthly Naltrexone Shot (Vivitrol), we have some answers for you. Just be aware that the Vivitrol shot is a fairly new thing on the scene, so experiences are going to be a little more scarce compared to say Methadone or Buprenorphine. Naltrexone is well known for its ability to block the effects of Opioids. This is well known and pretty indisputable. What we really don't know for sure, is how it alters the effects of other, non-Opioid drugs. Preliminary evidence would suggest that it has a pretty broad range of effect.

Alcoholism is one of the indications for the Vivitrol shot and Naltrexone in general. It doesn't block the effects of Alcohol completely, but it apparently reduces the euphoria and positive psychological effects of Alcohol, leaving you with just he physical effects, which frankly, really suck.

Other Drugs, like Cocaine and Amphetamines have also been noted to produce diminished effects when consumed by a user of Naltrexone. Just like with Alcohol, the effects aren't reduced to zero or "blocked", but the euphoria that you're after when using these substances seems to be greatly reduced. Sadly, this would indicate that Naltrexone and the Vivitrol shot do a fantastic job of curbing addictive behavior by effectively negating all positice effects of recreational substances. I'm really not sure how Cannabis is impacted by Naltrexone, but given its relationship with other drugs, I would say the prognosis is not good.

I've always said that I would need to be physically restrained and/or sedated for someone to give me the Vivitrol shot. I would never, never, never let someone or something chemically castrate me like that. Methadone maintenance is different in my opinion. It's a fair trade. I get an Opioid daily. It's not my favorite one, but it's an Opioid and it makes me feel normal. The Vivitrol shot takes away your choice, which is helpful for a lot of people, don't get me wrong, but it's not for me.
 
Well, SHUCKS that definitely solves that, Thanks Keif! yeah the euphoric magic has been reduced since first use of any drugs since getting the first shot, for sure, although not nearly as diminished as the present result of using these same drugs months later... (due to tolerance, Naltrexone residual buildup over the few months)... and i need to stay on this shot for at least 6 mos Minimum to continue to be welcome here at my parents home. Im working constantly and (i dont think) do not noticeably exhibit any signs of stim usage... after all, theyre so used to nodding out being the suspect behavior, and you bet your ass im not noddin out at this point in time....

I could possibly plead that the side effects are too substantial to continue and i wish to stop the injections based on that. However, then i would be tossed back into the Always-fearing-Drug-Test state of mind, as i have gotten used to not sweatin it lately bc they KNOW im not using opiates, so why test me...? After all, ive never had anything close to issues with anything but trees...

Honestly, this would be the song in the background if my life was a movie.. https://www.youtube.com/watch?v=WM7-PYtXtJM

Ya feel me? LOL all i want to do is just freely use my chemicals!!!! Not go back to heroin though, how to abstain from that for good..
 
Sorry to hear that Vivitrol a way more of a drag than original data suggested. But an even nastier "cure" is in the works. It is only targeted at Cocaine and Nicotine as of right now but I'm sure that will change.

"TA-CD is an active vaccine developed by the Xenova Group which is used to negate the effects of cocaine, making it suitable for use in treatment of addiction. It is created by combining norcocaine with inactivated cholera toxin.

It works in much the same way as a regular vaccine. A large protein molecule attaches to cocaine, which stimulates response from antibodies which destroy the molecule. This also prevents the cocaine from crossing the blood–brain barrier, negating the euphoric high and rewarding effect of cocaine caused from stimulation of dopamine release in the mesolimbic reward pathway. The vaccine does not affect the users "desire" for cocaine, only the physical effects of the drug."

https://en.wikipedia.org/wiki/TA-CD
 
So i have an update on my situation, after doing some thinking and talking to people. I have decided that i am going to discontinue the Vivitrol, not getting my next shot which is scheduled for the 24th.

Instead, i'm just going to go back to my daily Pregabalin regimen that i was on a number of years back, back when i didnt realize the true value of gabapentinoids and just wanted to use nothing but illicit drugs.

Id be lying if i said im not a little worried about how my feelings toward opiates may change a few weeks from now when the Vivitrol is all out of my system. Like i said in an earlier post, opiates have absolutely zero pull on me right now, and i really dont want to believe that its all solely because of the shot. The last few months have shown me that i truly CAN live, work and socialize without heroin, and be just fine. I know its possible... otherwise i probably would have cooked up a scheme to get off the shot earlier on if i really wanted to still run em.
 
Dude, you injected the microspheres in your muscle you're fucked, you gotta wait 40 days for the steady state to crash and the Naltrexone to come off the receptors. Even if you help it come off the receptors with some Heroin, the spheres will shit more naltrexone and you're back to where you started. Lol. Sucks to be you man.

Now you get to see what it's like when the opposite sex approaches you sexually and you feel mortified by it, roll your eyes and just wish you could escape the situation LOL!!!
 
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wonderful, another thread derailed by "master trole 2016" ksa. Whenever he's not being factually wrong, he's being puerile and childish.

But an even nastier "cure" is in the works. It is only targeted at Cocaine and Nicotine as of right now but I'm sure that will change.

Thankfully these vaccines don't interfere with the body's natural neurotransmitters... so at least on paper if you got them you'd be more like Case out of Neuromancer... drugs wouldn't do shit unless you found a nice analog :p

Part of why naltrexone has such a tendency for people to dislike it is because the body does use the opioid system normally! So when you take a drug that categorically blocks mu-opioid signalling you are effectively muting one of the major feedback/reward systems of the body.

Rimonabant (CB1 antagonist drug used for obesity) was actually pulled off market for the same reason - blocking the central cannabinoid receptors turned out to increase the risk of suicidal depression. Kind of a bad side effect in a weight loss drug. But you can imagine, THC is very good at producing feelings of contentment/enjoyment, now imagine having that blocked.... no euphoria from exercise or strong emotions? Count me out.

Anyway to answer the OP: thankfully naltrexone should only block the effects of opioids (and to an extent alcohol, too). It should not block cannabinoids, cocaine, amphetamines, MDMA, GHB, benzos, ketamine, PCP, nicotine, areca nut, or LSD/mushrooms/tryptamines. So you can have fun on those. Salvia divinorum should work too actually...
 
Ksa... i have no intention of going back to heroin at all. ive been without it for months and it the reason i started the Vivitrol in the first place. I am very confident that it served its purpose and i will bea ble to abstain from now on.

Ksa && keeping... i do appreciate the input, really, but... you two guys remind me of school children... think you're hurting MY feelings? lol im not that sensitive boys. Im well aware that ill have to wait another few weeks (its been 3 weeks since my last shot) and then ill be pretty close to normal, in terms of my sex drive and the effects i have been missing out on.. and for the record... i wouldnt consider my naltrex'd state of mind to be close to that of a womans LOL i have had sex a few times since being on the stuff, its still great, it just doesent hold as much importance to me throughout the rest of the day since starting the shot, and IMHO the ability to focus on other (more important) things like getting ahead at work instead of partying and mindlessly fucking girls.. is pretty great.

Sekio.. I can tell you as a matter of FACT that it 100% Does interfere with the [dopamine-releasing] action of methamphetamine (noticeably) and cocaine (much more noticeably). I hadnt done blow in years and about a week after getting my second injection, snorted up a whole gram of fishscale goodness in about 5 fat lines over the course of an hour (subsequent lines after the first done so quick and increasing in size due to the total lack of euphoria. I had all the speedy effects, just no euphoria. I could go back and attach a few links to articles where Naltrexone is mentioned as a principal method of "treatment" for cocaine users, due to the fact it blocks the desireable effects. I have even smoked a grip of hits of crack made from the same quality coke and not even got high at ALL. talk about frustrating. Thank god i didnt PAY for the coke... haha

The meth has had less and less effect, and is definitely affected less by the vivitrol, but definitely is, nonetheless, Im sure of it. However, i do also take into account the amount/frequency i have been using recently and know that plays a part too.
 
I just removed some posts that were not productive to the conversation. Please guys, stay on topic. Thanks!
 
I cant even remember what the deleted posts were even about... LOL but thanks nevertheless Mr. Calderone!
 
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