I would like to revive this thread because I believe doing so can provide information that apparently is nowhere to be found...
Viberzi is an agonist at the mu and delta opioid receptors, just as most of your run-of-the-mill opioid pankillers are, so why, by all accounts, has this medication not provided anything close to the same enjoyable effects provided by the others? The easy answer is it targets pain receptors in the bowels, rather than the brain. Now, I'd read one individual describe IV'ing this drug and he very much enjoyed it. (You can find this on a simple google search, and in fact it may even be on BL)
Anyway, I refuse to IV anything at this stage of my life, but what I did finally decide to do was try the insufflation ROA after all this time... Hey, maybe the effects will be totally different since this opioid will bind to receptors in the brain rather than the gut. I sucked the coating off and did just that. There is an INTENSE rush that hits you IMMEDIATELY -- from head to toe. Not entirely dissimilar from the physical sensation I described in this thread, although not with nearly the same level of discomfort. Again, very heavy-bodied feeling, and again absent any euphoria. This rush lasted about a half hour, and as it faded away the feeling became SLIGHTLY more opiate-like and pleasant, although still not something I will do again.
Also, though it doesn't necessarily burn, it is almost vomit-inducing in its taste (though this may be the fact that I generally dislike sniffing anything and haven't done so in years).
Dry mouth is extreme, no effects worth trying this again.
This is quite a unique and strange drug.
PS: Could I possibly be the first person to try this ROA and post about it online? Seems to be very possible.
I will reiterate again, this does not seem to a recreational drug whatsoever.