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Urgent!! What interactions could NBOME have w/ tramadol and pregabalin??!!

That's not quite true JG. Tramadol, when taken in an enormous overdose (from memory the figure in the research was something like 600-1000mg), can increase the risk of seizures in about 1% of people who take it if they are already vulnerable to seizures - such as epileptics.

Somewhere down the line that always gets shortened to "it increases risk of seizure". Only in epileptics taking a massive overdose.

My best friend took 400mg of tramadol and had a seizure and almost died a few years ago.
 
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