paracelsius
Bluelighter
- Joined
- Mar 11, 2020
- Messages
- 197
Here is a quote from some other forums:
The fact that Levamisole is a major ingredient of Cocaine in the US since quite some time now and that the expected massive outbreak of pulmonary hypertension did not take place raises some questions for sure.
It boils down to two possibilities:
- The whole "Aminorex causes pulmonary hypertension" thing is just utter bullshit (this is what I think*)
or
- only levo-Aminorex causes PH, not dextro-Aminorex. As Levamisole is a chiral medication of the "natural" configuration and it its metabolized to dextro-Aminorex alone.
But even IF it was true and all Aminorex would cause PH it would afflict at most 0,2% of those who use it daily for a prolonged time and as PH is a cumulative disease, say it must be triggered and existing to get worse and worse by self-reinforcement, just using 5 mg Sildenafil or Tadalafil daily will simply suppress the outbrake completely. Those meds were developed exactly for this and are prescribed in this doses for exactly this purpose and they work very well.
* I think Aminorex was slandered and pulled because it was in the process of getting FDA clearance not for weight-loss but as a medication for menopausal women to restore lost libido for them. What parts of the press and medical establishment slandered as a "Sex drug for women". I mean, it was still the 60's, early 70's back then. So yes, there was more to it then just weight loss and judging from the fight the test-groups put up when they were told that tests are discontinued and the drug banned it will have been a lot more I would say.
Synthesis is not as trivial as 4-MAR. Seems very similar to Amph/Meth where Meth is so much easier.
Aminorex is prone to Hydrolysis, so its more then questionable if Cyanates will give any yields worth to mention, not as far as I know. But well, what do I know.