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The Scientific Explanation Thread

Meep i should note im pretty secular & more concered with tribal affiliation over actual devout observance, but religion is handy as tool to maintain my family, do my job, provide a rough guide to whats right/wrong as it pertains to my individual ideals ~

Which leads me to believe that this question:

best question to ask any religious person is that if they were raised as a child in another country with another dominant religion, would they believe in that religion and shun their current one?

Is very interesting

In my case the answer would probably be yes, if i grew up as Muslim id pray in a mosque, ive my mother was Jew id pray in a synagogue.

Ive hammered this topic with folk from Rome to baghdad to Tel aviv & back again who all agree that we're taught to fear God so we don't fuck up, we all subscribe to the same newsletter..

buddy_christ.jpg
 
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Maybe its all about having faith and believing in our selves?!;) Whatever that may stand for :)
 
Sorry Zophen if your ramblings made a little more sense they would be much less conducive to misinterpretation.

Anyways...

The ground the KKK stands upon seems to be crumbling a bit further every day...

I bet Michael Jackson wishes he was privy to this information before he went and did whatever the god awful hell he did to his poor skin:

Skin colour: cracking the genetic code

SANDRA LAING has brown skin and curly black hair. Her appearance is typical of the coloured people of South Africa, descendants of European settlers, Malay slaves and local peoples such as the Khoikhoi. What's unusual is that Laing's parents were "white" Afrikaaners, as were her grandparents and great-grandparents. That she turned out to resemble a more distant ancestor should have been a mere curiosity - except that Laing had the misfortune to be born in apartheid South Africa back in 1955.

People like Laing, whose story is being turned into a film, illustrate the complexity of the genes that determine our skin, hair and eye colour. Her case, like those of twins where one has light skin and the other dark, has attracted much media attention. But they come as no surprise to geneticists.

"When you look at people of different pigmentation who have had children, it's quite clear there are discrete categories. One parent is fair, one is dark, but the children are not all in the middle," says Greg Barsh, a pigmentation geneticist at Stanford University School of Medicine in Palo Alto, California. "What that indicates is that while there are not one or two genes, there are not 10 or 20. There are probably 5 to 10 genes." We are now rapidly uncovering these genes - and the findings are throwing up some surprises about how skin colours evolved.

For many of those involved in the work, simply understanding the basis of colour differences is worthwhile in itself. "So much world history is ascribed to 'These people look different from me'," says Barsh. "I see providing answers as something that will remove some of the mystique and prejudice."

Meanwhile, law enforcement agencies hope for more practical benefits: they want to be able to generate a description of a person from a DNA sample found at a crime scene. Perhaps the most intriguing prospect is that as we work out exactly out what determines our colour, we may be able to develop ways to tweak it that are far more effective than anything that exists today.

The key to our colour is a dark pigment called melanin. The more melanin there is in skin cells, hair or the iris of the eye, the darker they are. It sounds simple, but there's more to it. For starters, melanin is not a single substance - its basic building blocks join to form various complicated chains. Rather than floating free within cells, these molecules are made inside little granules called melanosomes, whose size, number and distribution in the cells can vary. What's more, the melanosomes are not even made in the skin cells and hair they end up in; instead, specialised cells called melanocytes produce the melanosomes and dole them out to other cells via tentacle-like extrusions. How dark a person looks depends on variations in each step in the triggering, making, packing and distribution of melanin.

Sometimes one of these steps breaks down completely, causing abnormalities such as albinism. Studies of pigmentation disorders in animals and people have led to the discovery of more than 120 associated genes. Yet only a few gene variants have been found that contribute to the differences in normal human skin colour, and one of the most important was stumbled across only recently.

Keith Cheng, a cancer researcher at Pennsylvania State University in Hershey, was working with golden zebrafish, a strain whose stripes are paler than the typical black. This mutant was first found in an Oregon pet shop in the 1970s. Curious about its lighter colour, Cheng's team took a closer look and found that its skin cells have fewer, smaller and less dense melanosomes - just like those of lighter-skinned people.

As part of his work, Cheng needed to identify the mutation responsible for the fish's golden colour. It turned out to involve a gene now called SLC24A5, which codes for an ion-exchange protein that probably sits in the membrane of melanosomes.

Cheng's colleague Mark Shriver then suggested looking for variations in the human version, SLC24A5, in sequences collected as part of the International HapMap, a project to chart genetic variation in humans. The team found two variants, one of which was present in everybody of European descent.

To prove these variants affect skin colour, the researchers looked at which were present in people of mixed African and European descent. They found that those with one copy of the "golden variant" tend to have much paler skin. If both copies of the gene have the golden mutation, the skin is lighter still. They concluded that the golden variant is responsible for between 25 and 38 per cent of the difference in skin colour between Africans and Europeans. Cheng had stumbled upon one of the key genes determining skin colour (Science, vol 310, p 1782).

"One of the questions I get asked is, 'Does this mutation alone make you white?'" Cheng says. "The answer is no." That is, you can have light skin without the golden variant: Japanese and Chinese people have the same form of this gene as the Yoruba of Nigeria. You can also have dark skin with the golden variant: up to half of Sri Lankans have the golden mutation, recent studies have shown.

Clearly there is far more to skin colour than SLC24A5. A variation in a gene called MATP (also known as SLC45A2, which probably makes another melanosomal transport protein, also contributes to the light skin of Europeans. And variations in the gene for tyrosinase, the enzyme that produces the building blocks of melanin, may also play a role, according to a genetic survey published in December by a team including Shriver (Molecular Biology and Evolution, DOI: 10.1093/molbev/msl203).

To the researchers' surprise, their findings show that the light skins of east Asians and Europeans evolved separately: the dark forms of SLC24A5 and MATP are the ancestral forms, and only after modern humans migrated out of Africa did SLC24A5 mutate in one individual, giving rise to the golden variant. The MATP variant appeared in a separate individual, either earlier or later. Both variants spread rapidly among the ancestors of modern Europeans.

"We expect there will be other genes that will fit the bill for east Asians," says lead author Heather Norton of the University of Arizona in Tucson. While the study identified variants in two pigment genes that are common in Asian populations, it is still unclear if these variants affect skin colour.

It could turn out that every distinct human population has unique skin-colour gene variants, but there are also some that we all share. In two genes that influence skin colour, Norton found variants that were common to all the groups her team looked at, suggesting these arose before modern humans dispersed.

So why did different populations evolve different skin tones? The leading theory, proposed by Nina Jablonski, also at Penn State, is that our colour reflects a balance between conflicting needs. Not only can sunlight damage our skin, it also breaks down folic acid (also known as folate), an essential B vitamin. On the other hand, we need ultraviolet light to make vitamin D.

Jablonski and colleagues have shown that skin colour around the planet correlates more closely with winter UV levels than with summer levels (New Scientist, 12 October 2002, p 34). This suggests that our skin colour has evolved to optimise folic acid and vitamin D levels during winter, with tanning allowing us to adapt to higher UV levels in summer.

If the folic acid hypothesis is correct, the diet of our ancestors was as important as UV levels in influencing colour. It has been suggested that early European farmers ate little vitamin D, making very light skin an advantage, whereas peoples like the Inuit got so much vitamin D from their fish-rich diet that they have retained relatively dark skin despite living in the far north.

There are other possibilities. Mutations that make skin lighter could simply have persisted in regions where this feature is not a disadvantage. However, the fact that the same variants spread among almost all Europeans shows there was strong selection for them. And while sexual selection could have played a role in this most visible of characteristics, the latest evidence fits well with Jablonski's ideas. "Natural selection should leave a stronger signature, and that's what we see," says Shriver.

Indeed, while most researchers had assumed that light skin evolved only once, Jablonski predicted that similar skin colours evolved separately in different populations as modern humans dispersed into regions with different UV levels. "I am now eager to see genetic evidence that darkly pigmented skin evolved more than once: for instance, in the ancestors of modern equatorial Africans, southern Indians and Sri Lankans, and indigenous Austronesians," she says.

Despite the rapid progress, there is much left to discover. "There are some major parts of the world where we don't know what to expect," Shriver says. Only a few groups in Africa have been studied, for instance, despite the large variation in skin pigmentation across the continent.

What we do know, though, could soon be put to use. Murray Brilliant of the University of Arizona College of Medicine in Tucson has shown that variations in just six genes accounted for 50 to 80 per cent of the differences in eye, skin and hair colour among 800 individuals he studied. Those genes included SLC24A5 and MATP. The work was funded by the US National Institute of Justice, which is interested in building up a picture of suspects when DNA samples draw a blank against police databases.

In fact, a cruder form of DNA testing is already being used for this purpose. DNAPrint Genomics of Sarasota, Florida, sells police forces a test that reveals people's ancestral origins, thus giving some idea of what a suspect might look like. The company says its test has been used in around 150 cases in the US and UK. Looking directly at the gene variants that affect appearance will be more accurate, however, and DNAPrint has already developed such a test for predicting eye colour. Brilliant's work could lead to tests for skin and hair colour as well.

For others, the goal is to change skin colour by manipulating melanin levels. There is a huge market for products that claim to do this. "People generally do it for cosmetic purposes alone," Cheng says. Others wish to treat dark or light patches, from age spots to more serious pigmentation disorders.

Most existing products leave a lot to be desired. Take skin lighteners. Hydroquinone, long the key ingredient in many of these creams, was thought to work by inhibiting tyrosinase, the enzyme that helps make melanin. Now it seems that it works by killing melanocytes and may be carcinogenic, leading many countries to ban it.

What's more, most products are not very effective. "It's very difficult to distinguish treated skin versus untreated skin," says Genji Imokawa of the Tokyo University of Technology in Japan, who worked on skin products for 35 years at Kao Corporation. You can measure the difference, he says, but it's not easy to see just by looking. The exception is monobenzylether of hydroquinone, which completely and permanently depigments the skin, apparently by destroying melanocytes. It's drastic, but can give people with severe pigmentation disorders an even skin tone.

Darkening the skin is also tricky. Most attempts to boost melanin levels have focused on synthetic versions of MSH, the hormone that causes tanning after sun exposure (New Scientist, 7 May 2005, p 40). The trouble is, such products may do least for those who need them most - fair-skinned people who tan poorly have mutations in the receptor for MSH, called MC1R. Hence the interest in forskolin, a compound recently found to activate a later step in the tanning pathway. It darkens the skin of mice even if they have mutations in the MC1R gene (Nature, vol 443, p 340).

While efforts to develop conventional drugs continue, genetic discoveries could lead to a whole new approach based on RNA interference - using small bits of RNA to switch off specific genes. The trick will be getting these "siRNAs" into the melanocytes. "The skin is a formidable barrier," says David Fisher of Harvard University. But if it can be done, RNA interference could open the way to the creation of lotions that gradually produce dramatic changes in skin colour and would only need to be applied once a week or less.

Already, cosmetics company Avon has filed a patent for lightening skin by using siRNAs to switch off the tyrosinase gene (patent number WO2005060536). The patent says the method has been tested on isolated mouse melanocytes and outlines ways of delivering siRNAs to melanocytes in situ. Avon would not discuss details with New Scientist but says that the research is continuing.

If this kind of approach proves successful, our skin colour might one day become almost as easy to change as hair colour is today, freeing us from the constraints of our genes.

It would, after all, make a lot of sense to adjust our skin colour to suit the local climate. And being able to choose our colour would make life far harder for those who still insist on judging people on the basis of a handful of gene variants.
Jessica Marshall is a freelance science writer based in Minnesota
From issue 2594 of New Scientist magazine, 10 March 2007, page 34-37

25941701.jpg
 
It's an education , that I can say , I just don't have the inclination to read 99.9% of the stuff you pull from varying journals !
But it's different and for that lostpunk I award you 23 bluelight points!
 
Magnetic Implants

http://www.bmezine.com/news/pubring/20060115.html

...the basic concept is that if you implant small magnets under the skin, they will move in response to an electromagnetic field and transfer this as sensation to the surrounding nerves. This in effect allows one to extend “vision” (or touch) into the electromagnetic spectrum...

Some dude writes about his experiences after 6 months with the implants.

It’s hard to exactly describe what it feels like — it’s definitely not as simple as “I can feel the implant vibrating under my skin”, which is true, but I am completely unaware of the presence of the magnets... It’s more like being able to “touch” the EM field. It’s very tangible, and the best way I can describe it is a combination of vibrating air and a strong sense of static electricity.

I'd love a set of these but its a shame about when you damage the silicon sheath (as this guy did) it leaks unknown crap into your body
 
What is the scientific basis for m4dd0g's extreme attractiveness? Do you have the Heartthrob Gene? Do you mate often?
 
Hey m4ddog that is pretty cool. I can see how it would be extremely helpful to anyone working in IT. It kind of reeks of stupidity to put relatively untested chemicals beneath ones skin.

Here are two recent articles from New Scientist which are pretty scary. They outline the fact that what we are going through in Australia is not a drought but the first signs of climate change. I mean how many years are we going to keep calling it a drought?

Also it outlines how stupid it is of Syndey and Central Coast governments talking about rolling back water restrictions (from Level 4 to Level 3) because of the recent rain. My local council is calling the (undecided so far thankfully) plan, a gift to residents for being so vigilant over the last 5 years with water usage. Isn't drinking water for the next 50 years gift enough? It's not about rewards, it's about survival. We've got a decent amount of rain for the first time in years and now we want to fucking splurge it. Bollocks!

The first is an editorial and is written by our very own Tim Flannery, Australian of the Year...

Editorial: Australia - not such a lucky country


OVER the past 50 years southern Australia has lost about 20 per cent of its rainfall, and one cause is almost certainly global warming. Similar losses have been experienced in eastern Australia, and although the science is less certain it is probable that global warming is behind these losses too. But by far the most dangerous trend is the decline in the flow of Australian rivers: it has fallen by around 70 per cent in recent decades, so dams no longer fill even when it does rain. Growing evidence suggests that hotter soils, caused directly by global warming, have increased evaporation and transpiration and that the change is permanent. I believe the first thing Australians need to do is to stop worrying about "the drought" - which is transient - and start talking about the new climate.

While the populated east and south of Australia have parched, rainfall has increased in the north-west. This has prompted some politicians to call for development of the north, including massive schemes for dams and pipelines (see "The continent that ran dry"). Some have even called for a large-scale shift of population to follow the rain. Yet computer models indicate that the increased rainfall is most likely caused by the Asian haze, which has pushed the monsoon south. This means that as Asia cleans up its air, Australia is likely to lose its northern rainfall. Australians need to leave behind their dreams of opening a new frontier and focus on making the best of the water remaining to them where they live today.

To achieve this, much has to be done. Industry, power plants, farmers and households pay too little for their water, so they waste it. Water thrift is an absolute prerequisite for life in the new climate. The country also needs to shift to a new energy economy. Australia's coal-fired power plants consume around 2 tonnes of water - for cooling and steam generation - for every megawatt-hour they produce. They also emit much of the CO2 that is the ultimate cause of the drying. Dwindling water supplies are raising the price of electricity, and to avoid an economic and environmental disaster the old coal clunkers need to be closed as quickly as possible and replaced with cleaner, less thirsty means of power generation. These could include geothermal, solar thermal, solar, wind or wave energy, and possibly clean coal.

Australia needs to design and build an irrigation system fit for the 21st century. It is tempting is to try to fix the existing system, but that is hopeless. The country needs to move to highly efficient irrigation and to think laterally about water use. As the climate becomes more variable it may make sense, for example, to plant rice and cotton during the odd wet year, rather than persist with permanent plantings of grape, citrus and so on, which need water year-round.

The cities need drought-proofing by, for example, installing water tanks in all dwellings that can accept them. Because in affected areas the decline in river flow is three times that in rainfall, water tanks that use roofs as catchments are now far more effective than dams for supplying drinking water in cities such as Sydney and Brisbane. Recycling can help too. This needs new investment and in some instances will require state government water monopolies to be broken up. It will cost more, but the benefits in terms of water security and recapture of nutrients in solid wastes are immense.

Desalination plants can provide insurance against drought. In Adelaide, Sydney and Brisbane, water supplies are so low they need desalinated water urgently, possibly in as little as 18 months. Of course, these plants should be supplied by zero-carbon power sources.

Last, but by no means least, Australia must ratify the Kyoto protocol and agitate globally for a swift and decisive reduction in greenhouse gas emissions. Our best theories show that Australia is suffering early and disproportionately from climate change. As one of the two renegade developed nations not to have ratified the treaty (the other is the US), and as the world's worst per capita emitter of CO2, some may say that Australia deserves its fate. If it is to save itself from even more severe climate impacts the country needs to change its ways, and fast.


Tim Flannery is professor of earth and life sciences at Macquarie University, chair of the Copenhagen Climate Council, and the 2007 Australian of the Year
From issue 2608 of New Scientist magazine, 16 June 2007, page 5

Australia - the continent that ran dry

IN THE beginning the Australian drought was fun. A talking point over the barbecue, an excuse to shower with a lover or spend more cloud-free days with friends at the beach. Tales of thirst-crazed camels rampaging through country towns merely added to the excitement.

Sometime last year, the mood changed - perhaps with the first inkling that water restrictions had all but destroyed urban gardens and that agricultural production across the country had fallen by a fifth. Last month, when water storage fell so low that energy supplies were threatened, the sense of panic became palpable. Australia is facing a national crisis, one that promises to transform the country, inexorably changing where people live, what they eat, what they do in their spare time, and - most threatening of all - their future economic well-being.

Whether Australia can adapt remains to be seen, and water experts around the world will be following closely as regions as far afield as the south-east and south-west US, and south-west China grapple with their own droughts. "Water will still come out of the tap, but at what cost?" asks Chris Mitchell of CSIRO Marine and Atmospheric Research (CMAR) in Melbourne. "Will we adapt and ameliorate the problem or adapt and exacerbate it."

Across the continent, average rainfall has actually increased marginally over the past century. But there has been a shift in where rain falls. Since the 1970s the unpopulated regions of the north have got wetter, but the southern and eastern regions, where most people live, are drier.

To make matters worse, Australia's average temperatures have been increasing at an accelerating rate in the past 20 years. Seven of the past 10 years have been hotter than average, and four states have just clocked up their warmest autumn on record. Higher temperatures increase evaporation, making a bad drought even worse.

Today large swathes of six of Australia's seven states and territories, and all of Australia's major cities, are officially "in drought" and have been for years. That's in spite of the rain that has fallen over the past few weeks, and the once-in-30-years storms and floods that hit Hunter valley, north of Sydney, last weekend. Because the land is bone dry, it has simply sucked up the rain. That has helped some farmers but water run-off is still well below average and the level of reservoirs remains perilously low (see Diagram).

Melbourne's water storage stands at 28 per cent of its capacity. Sydney's is at 37 per cent. Perth, where rainfall has fallen 15 per cent in the past half-century, and inflows into the dams by more than 40 per cent, now accepts drought as the norm, and has dropped its expected annual catchment from 340 to 180 gigalitres. Last year, just 120 gigalitres flowed into its dams.

"People have been taken by surprise at the speed this has happened," says John Langford, director of UniWater, a research initiative shared by Monash and Melbourne Universities. What makes the Big Dry more shocking is that just 10 years ago, Australia was considered drought-proof. Precisely because the country is so susceptible to huge variations in rainfall, the nation-builders of the 1950s and 1960s equipped city and country with massive multi-year reservoirs, providing the highest water storage capacity per capita in the world, and plumbed in hundreds of kilometres of irrigation channels. What they hadn't bargained for was the thirst of the country's growing population, or just how brutal a drought could be.

Australia sits at the centre of three oceans, the Indian, the Pacific and the Southern. Its reputation as the driest inhabited continent on Earth, and the one with the most variable rainfall (in the 1970s, large parts of Australia were beset with floods), depends on a complex interplay between these oceans and the atmosphere.

The best understood system is the El Niño-Southern Oscillation. During El Niño events, which usually peak in the Australian summer, warm water develops in the eastern and south-eastern tropical Pacific, triggering differences in air pressure that drive rain that should fall onto eastern Australia out over the ocean. Australia has had two such El Niños in quick succession, one in 2002 and 2003, and one in 2006 and 2007, with no intervening wet periods.

Since 1997, the Indian Ocean Dipole - a cooling of the tropical eastern Indian Ocean, and a warming of the west - has also been more active, reducing spring rains in south-east Australia. Finally, winter rains have dropped off due to changes in the Southern Annular Mode, a climate pattern that prevents rain-bearing low-pressure systems reaching southern Australia.

A large portion of the drought-inducing changes is undoubtedly due to natural variation. But there is the possibility that climate change, especially rising temperatures, has turned a severe drought into a historic one. In Australia's worst-hit region, Perth and the south-west, increases in greenhouse gases account for about half of the reduction in rainfall, according to an analysis of 70 experiments using 21 climate models by Wenju Cai of CMAR and CSIRO colleague Tim Cowan (Geophysical Research Letters, vol 33, p L247098).

For many water experts the spectre of climate change makes arguments over the cause of the current drought almost irrelevant: the most recent assessment by the Intergovernmental Panel on Climate Change was confident that climate change would make the southern regions of Australia where most people live warmer and drier, and more susceptible to extreme variations in weather. In other words, Australia may survive this drought, but there will be more to come.

"For our major cities, supply will fail to meet demand by 40 per cent by 2025. We will need another 800 to 1000 gigalitres per year," says Tom Hatton, director of CSIRO's Water for a Healthy Country Flagship. In comparison, Perth, Australia's fourth largest city, uses 300 gigalitres a year. "That's based on projected population growth, and in hindsight, on rather optimistic estimates of the improved efficiency with which we can use water, and rather conservative estimates for declines in rainfall."

Can technology keep the water flowing? All but the greenest policy-makers now see desalination plants as essential, at the very least as back-ups to see Australia through this and future droughts. But you need huge amounts of energy to pump seawater through membrane filters, and the waste brine created by desalination is bad news for the environment.

Perth completed its first desalination plant last year, with a new wind farm being built to supply the electricity and offset the 24 megawatts required to run the plant. Desalination now supplies 17 per cent of the city's drinking water and a second plant has been commissioned. Sydney is building one, and Melbourne is expected to follow suit. Industrial plants which depend on a secure water supply, such as BHP Billiton's copper and uranium mine in South Australia, are considering building their own large desalination plants.

Recycling waste water could be a more sustainable option because it uses roughly a third of the energy required to desalinate seawater. But last year Toowoomba, Queensland's largest inland city, overwhelmingly voted to reject adding recycled effluent to the water supply, making politicians elsewhere nervous about introducing similar measures. Nonetheless, Queensland's government hopes to start recycling sewage before Brisbane's main water supply runs dry early in 2009. Most experts agree that recycled water will be supplementing Australian drinking supplies within the decade.

Even the politically unpopular and costly option of piping water from one catchment area to another - robbing Peter to pay Paul - will become more common. "Desalination, recycling and piping all cost more energy per unit volume of water than traditional reservoirs," says Hatton. That worries climate experts, because more energy tends to mean more greenhouse gases, which in turn will exacerbate climate change and future droughts.

Hatton believes we can still save the day by reducing demand for water, for example by increasing its price, and by making the same water stretch further. The Water for a Healthy Country Flagship is developing new techniques to bring down the economic and environmental costs of desalination and recycling, and to improve how water use is measured, which in turn will make water use more efficient. It is also working on new storage techniques, including "managed aquifer recharge", in which partly recycled water is pumped into underground aquifers. Not only does that reduce evaporation, which can be significant from a dam surface, but water quality also improves with time as pathogens die off.

Not everyone is convinced this will be enough. "You can fiddle around with technology, but there is a limit to the amount of water available. Population needs to be part of the discussion," says Graeme Pearman, director of the Monash Sustainability Institute at Monash University in Melbourne. He and others say people are failing to address the impact of Australia's burgeoning population, expected to grow from 21 million to between 25 and 33 million by 2051, for fear of appearing racist or anti-development.

That attitude may be starting to change. In March, delegates at a high-profile conference in Canberra on population and water use discussed the need both for a national population policy that took into account the scarcity of resources such as water, and for more strategic regional planning that ensures new settlements follow the water rather than vice versa.

Barney Foran, a policy analyst at The Australian National University in Canberra, says Australians must also address their per capita water use. When you factor in the water used to make products such as food, drink, clothing and newspapers, the average Australian consumes roughly six to eight times more water than what their domestic water meter records, with more affluent Australians consuming twice as much as less affluent ones.

Meanwhile, illogical as it seems, the biggest obstacle to dealing with an ever drier Australia could be rain itself. "We have a window of opportunity," says Quenton Grafton of The Australian National University. "My concern is that if the drought breaks then people's attention will move on to something else. Five years down the track when we have another drought - which will happen - we won't be ready."

26085301.jpg


13 June 2007
NewScientist.com news service
Rachel Nowak


Murray river system dries up

Talk about drought in Australia, and conversation quickly turns to the Murray-Darling Basin (MDB). This monster river system symbolises the difficulties of divvying up an ephemeral resource like water.

The rivers of the MDB cross four states and one territory, each of which hands over some of its water management responsibilities to a mishmash of often overlapping local authorities. Add in a shrinking water supply, a growing population, and the competing needs of irrigation, industry, the environment and water for drinking, and it is easy to see why no one's happy.

Long before the current drought, water extraction had pushed the MDB to breaking point, slowing its rivers, increasing their salinity and nutrient concentrations, and altering their temperatures. With the drought, farmers, who rely on the MDB to produce 40 per cent of the nation's food and fibre, are suffering too - their pain became international news in April when Prime Minister John Howard announced that they won't see a drop of irrigation water until significant rains fall.

Nor are city dwellers happy. The Murray was once the most reliable source of water for Adelaide, a city of 1.1 million. Now the river threatens to fall below the level of the pumps.

The latest attempt to rectify the situation is Howard's "National Plan for Water Security", revolving around revamping irrigation in the MDB. Its aims, to give farmers less water and to better police and measure water in the basin, have won support from water experts. Others fear that plans to plug leaks in the hundreds of kilometres of decrepit irrigation channels will backfire on the environment: up to 60 per cent of the leaking water returns to the rivers, bolstering what little flow there is.

What everyone agrees is that agriculture in the MDB will change. At the very least, the amount of irrigated pasture for dairy will decrease. Some farmers may even move to the wet, northern reaches of the continent - an option being examined as part of Howard's new plan.

"The current pattern of agriculture and settlement was based on a certain set of climatic conditions. If they don't continue, everything gets thrown up in the air," says Daniel Connell of The Australian National University in Canberra, author of Water Politics in the Murray-Darling Basin.

Keeping cool over energy

"You can't put a tight little boundary around the water issue," says Barney Foran, a policy analyst at The Australian National University in Canberra. As well as being a trade, environment and population issue, it is an energy issue, he says.

In the last few months dwindling water supplies have forced Victoria's major power stations to buy in water for cooling to supplement local sources. Queensland has turned off two of its generators, reducing its total capacity by 700 megawatts. Meanwhile, dams holding water to power hydroelectric turbines in the snowy mountains of New South Wales are at their lowest levels, containing just 8 per cent of the water once available for power generation. That has forced the government to temporarily waive environmental restrictions to allow fuller use of gas-fired power plants.

Water scarcity has also helped double the wholesale price of electricity from A$30 ($25) to A$60 per megawatt-hour. According to a recent report from the National Electricity Market Management Company, which manages most of Australia's electricity supply, the lack of water could cut the total energy available by up to 10 per cent by late 2008. Such a shortfall would drive up electricity prices, and lead to rationing and rolling blackouts during the summer, when air conditioners send electricity consumption soaring.
 
It's pissing down in Britain, weather forecasters are threatening ground frost as well.:! It is summer though so what could we expect. :\

A FYI lostpunk ;)
 
Does Anyone Remeber That Shark On Sesame St. With Those teef He Sung About?

lostpunk5545 said:
I'd rather burn in purgatory for eternity than share heaven with a god that would give a species freedom of thought and then punish them for exercising it.

Dude,
you can't burn in purgatory-
that's jus' where you hang out,
t'til He figures you're ready to
pitch your case
to St. Pete.

Anyways,
I thought you'd like to get up there
& give HIM a right
smite-a-thon
fo' that free thought stunt.

;)
 
Thanks Fo' All The Articles... I Love This Thread

^
^
An' you coulda used those
NSW legs
las' week...
;)

Hope it's dryin' dude.
:\

PEACE
UnS
:)
 
^Had a little rain in OZ then I presume.
 
There was a pretty bad storm that hit Sydney and to a greater extent a bit further North.

I got 2 feet of water throughout my house... Fun times :)

No worries Unsquare!
 
I read this article today and found it hella creepy. One explanation for this disorder, if it exists, is that the strands of fibre are related to fungi. Considering that fungi digest their food by theoretically putting their 'intestines' (mycelium and hyphae) through their food and then absorbing its nutrients from the inside...

Morgellons disease: The itch that won't be scratched

STEVE JACKSON* wants to know what is going on in his body. For years he has been finding tiny blue, red and black fibres growing in intensely itchy lesions on his skin. "The fibres are like pliable plastic and can be several millimetres long," says Jackson, an officer in the British army. "Under the skin, some are folded in a zig-zag pattern. These can be as fine as spider silk, yet strong enough to distend the skin when you pull them, as if you were pulling on a hair."

Jackson is one of thousands across the US, Europe and Australia who are reporting similar symptoms. "I've had lesions containing black fibres all over my arms, legs, ears and face, with itching, crawling sensations," says Pamela Winkler from Maryland. "It feels like something is biting you everywhere."

The biting, crawling sensations and itchy fibres make sufferers suspect that a parasite is involved. Yet anti-parasitic medications don't seem to have any effect. "I've spent a fortune on dermatological creams but nothing worked," says Julia Ormerod from Devon, UK. Ormerod has had her house checked for infestation, hoping to find the cause of the lesions and the itchy, pepper-like black specks that she keeps finding on her skin. Nothing was discovered.

Fibres are only part of the problem. Sufferers are also affected by chronic muscle and joint pain, severe fatigue and cognitive problems. "I walk into rooms and suddenly forget what I'm doing there," says Sarah Jones* from Somerset, UK. "My words get jumbled when I talk." As the condition progresses, paranoia and depression become common, in some cases leading to suicidal tendencies.

Ask Jackson, Winkler or many others with similar symptoms what is wrong with them and they will tell you that they have something called "Morgellons disease" (pronounced with a hard "g"). Yet mainstream doctors recognise no such condition and say that Morgellons is just a new and unhelpful name for a well-known psychiatric illness. Research into the condition, meanwhile, routinely produces more questions than answers, and now the US Centres for Disease Control, based in Atlanta, Georgia, has stepped in to sort out the mess. What is going on?

The Morgellons mystery was sparked back in 2001 when Mary Leitao of Pittsburgh, Pennsylvania, suspected that her 2-year-old son Drew had scabies. After treating him with a cream she found tiny bundles of fibres emerging from his skin. She contacted doctors but felt that none took her seriously. "Several physicians concluded that the fibres were coming from either my son's clothes, or my clothes," she says. After searching for information, she found a monograph by the 17th-century author Thomas Browne describing "the Morgellons", a long-forgotten illness characterised by black hairs protruding from the skin. She appropriated the name and set up a non-profit organisation, the Morgellons Research Foundation (MRF), in the hope of attracting advice or help from scientists. To her surprise, she began receiving thousands of emails from people claiming to have the same thing. To date, more than 10,000 families have registered on the site.

Yet on presenting typical Morgellons symptoms to doctors and dermatologists, people consistently find themselves being told that it is all in their heads. Rather than suffering from a mysterious infection or parasite, doctors say they have a well-documented psychological disorder called delusional parasitosis (DP).

DP is characterised by an unshakeable belief that sensations of itching and crawling on or under the skin are caused by parasites such as lice, fleas or worms - even in the face of incontrovertible evidence to the contrary. The condition usually occurs in people with other psychiatric conditions such as bipolar disorder, paranoia or schizophrenia, and in cocaine and amphetamine abusers.

Matchbox sign

"I was told that the sensations were being caused by my nervous system," says Ormerod. "Dermatologists took a small biopsy of my skin but said they didn't find anything. They just told me to stop scratching myself and the itching would go away. It didn't." Jones's appointments with doctors similarly came to nothing. "They sent fibre samples to a lab for testing. All they would tell me was that nothing abnormal had been found."

What doesn't help is that Morgellons patients often develop psychological symptoms such as depression and paranoia - hallmarks of DP. They also have a tendency to bring in small containers of fibres to their doctor as evidence of a parasitic infestation. This, too, is a classic symptom of DP, known as the "matchbox sign". "When you look at them, the [DP patients'] samples inevitably turn out to be skin, lint, scabs, or household debris or fibres," says Lynn Kimsey, director of the Center for Biosystematics at the University of California, Davis.

Most experts have little doubt that Morgellons is actually DP. "Claiming Morgellons disease is a case of people making a connection where there isn't one," says Kimsey. "They are advocating some unknown disease, but these are the same kind of symptoms that we see with DP sufferers."

And the lesions? Likely to be self-inflicted, says Jennifer Biglow, a dermatologist at Skin Specialists, a private clinic in Minneapolis, Minnesota. Many DP patients, says Biglow, are neurotic excoriators, creating the lesions themselves because of a constant need to pick and scratch at their skin. "When they pick, they get temporary emotional relief," Biglow says. The broken skin attracts household fibres, and exposes bundles of collagen and elastin from under the skin. To someone with DP, any of these can easily take the appearance of a parasite.

"To my knowledge there is no evidence presented so far that convinces me that Morgellons patients are infected with any organism known to western science or related to anything or any parasite we currently know," says Noah Craft, a dermatologist at the University of California, Los Angeles.

Spurious cases

Some experts are even concerned that the Morgellons Research Foundation and its made-up disease are having a negative effect on public health. "Individuals with DP are very sick psychologically and badly need help," Biglow says. "When they read about Morgellons disease they get emotional comfort and temporarily feel better about themselves." The result, says Biglow, is that many DP cases are missing out on the treatment that could really help them: antipsychotic drugs.

Others worry that they will be inundated with spurious cases. "As more and more of our patients discover [the MRF website], there will be an ever greater waste of valuable time and resources on fruitless research into fibres, fluffs, irrelevant bacteria and innocuous worms and insects," wrote Caroline Koblenzer of the University of Pennsylvania in Philadelphia in a stinging commentary in the Journal of the American Academy of Dermatology (vol 55, p 920).

Mystery solved? Not according to the handful of researchers who believe the DP explanation for Morgellons leaves too many questions unanswered. Randy Wymore, a pharmacologist at Oklahoma State University (OSU) in Tulsa, is one of them. About two years ago, Wymore chanced upon the MRF and was struck by how many people claimed to have the fibres. "I thought it would be easy to determine whether the fibres were real or not, and what they were."

Wymore contacted MRF to say that he would be willing to examine some samples, but secretly expected none to arrive. "When you ask a DP patient to show you physical evidence of fibres they commonly make excuses such as: 'Only someone who has it can see them,' or: 'If I post them to you they will disappear in the mail.'"

Within days, however, samples were pouring in. What surprised Wymore was that, under the microscope, fibres from different people looked remarkably similar to each other and yet seemed to match no common environmental fibres.

Wymore asked his colleague Rhonda Casey, a paediatrician, to examine some patients. Using a dermatoscope - a microscope used for examining skin - Casey clearly saw fibres. These were not just embedded in lesions but were also visible under the surface of unbroken skin and could be removed with tweezers. She observed nothing like them in a control group comprising both healthy patients and those with other dermatological conditions. Wymore and Casey are now working on a case study to submit to a peer-reviewed publication.

They also took samples to the Tulsa police forensic science team. On first inspection, the forensics experts agreed that the fibres were not from clothing, carpets, towels or bedding. Using spectroscopy they were unable to match the fibres to any of the 880 compounds commonly used in manufacturing commercial fibres. Dye-extracting solvents released no colouration.

Finally, they tried gas chromatography, gradually heating the fibres to around 370 °C and recording which compounds vaporised off. Save for giving off a small amount of carbon dioxide, however, the fibres remained intact. "Any organic material should normally be vaporised and the inorganic components reduced to ash by the time you get to the top temperature," Wymore says. "But all that happened was that the fibres darkened. We were shocked, and the forensics team were completely blown away." The team say they will submit their findings to a journal once they have an idea of what the fibres are, rather than what they are not.

One researcher who believes he already knows is Ahmed Kilani, director of Clongen Laboratories, a private research organisation in Germantown, Maryland. Kilani says that he managed to break down two fibre samples sent to him by a Morgellons sufferer using protein-digesting enzymes and extracted DNA from them. When he sequenced the DNA, he found that it belonged to a fungus. This makes sense, Kilani says: many fungi embed a root in their host and send out long filaments called hyphae. "This is what the fibres could be," he says. Clongen has not charged the patient for its services and now plans to apply for a government grant to carry on the work.

However, at Stony Brook University, part of the State University of New York, biochemist Vitaly Citovsky has another idea. He found that Morgellons lesions contain Agrobacterium, a genus of bacterium that causes tumours in plants. Control groups test negative. In 2001, when he knew nothing of Morgellons, Citovsky discovered that Agrobacterium, which is used commercially to produce genetically modified plants, is - under laboratory conditions, at least - able to insert its DNA into human cells. This is the only recorded example of trans-kingdom DNA transfer (Proceedings of the National Academy of Sciences, vol 98, p 1871).

Could Agrobacterium be causing a new human disease? "We don't yet know," Citovsky says. "Agrobacterium could just sit there in a lesion, like an opportunistic infection. Or it could genetically transform the host, as it does in nature with plants. The next stage will be to infect mice with Agrobacterium and see if we can recreate the disease."

Meanwhile, Robert Bransfield, associate director of psychiatry at Riverview Medical Center in Red Bank, New Jersey, has tried treating Morgellons patients with antibiotics and has seen significant dermatological and psychiatric improvements. "If it was placebo, anything you gave them would help. But only certain antibiotics work."

It's not just the identity of the fibres and the possible infectious agent that is attracting attention. A handful of psychiatrists are also starting to question the assumption that Morgellons is simply DP in disguise. "Before the onset of their illness, these patients' mental status appeared to be quite representative of the general population," says Bransfield, who has reviewed MRF's database of 3000 patients. "Many are high-functioning professionals. Their symptoms are not compatible with substance abuse or other recognised causes of delusions. What confuses it is that in the later stages, some Morgellons patients do become paranoid and delusional. But it doesn't start out that way."

There's also the question of Leitao's son. Is it possible for a 2-year-old to suffer from DP? "Since entering medical school in 1968, I don't recall seeing a single case I would diagnose as delusional parasitosis in a child," says Bransfield. Even Biglow is doubtful. "In my opinion a child of two years of age would be too young to suffer from DP," she concedes, though she points out that parents with DP can believe their children are infested.

Bransfield also has a hypothesis for the cause of the mental symptoms: they are caused by the body's reaction to a real parasite. The process is triggered when a parasite invades a host and the host's innate immune system unleashes an inflammatory response, mediated in part by protein messengers called cytokines. Cytokines also produce symptoms in the host. "The fever, aches, pains and fatigue that you feel when you have influenza are not a direct result of the virus," says Bill Harvey, a doctor based in Colorado who has seen about 75 patients claiming to have Morgellons. "They are generated by your cytokines defending you."

In the short term the reaction works fine, but if an infection persists, the continuing action of cytokines can have a "friendly fire" effect on the nervous system, resulting in psychological illness. In some diseases, including hepatitis C and Lyme disease, the body's reaction to infection is known to produce mental illness. Could Morgellons be the same?

It's hard to say. Most of the ideas and research have yet to be formally published, leaving believers and sceptics to slug it out on websites such as Morgellonswatch.com and Wikipedia. Where Morgellons does appear in the peer-reviewed literature it is mostly as an awarness-raising exercise from one side or the other. Last year Leitao herself, in collaboration with two sympathetic medics, published a paper describing the condition (American Journal of Clinical Dermatology, vol 7, p 1).

Formal investigation

As the research process grinds into gear, more and more people are coming forward. Wymore, who recently set up the Center for the Investigation of Morgellons Disease at OSU, gets more than 70 emails per day from people asking for help or information. "I can't even answer my office phone any more - there are too many Morgellons calls," he says. "One guy drove 1600 kilometres from California just to ask me to examine his fibres."

The ever-increasing number of people clamouring for answers, coupled with requests by doctors for help in dealing with this condition, has led the US Centers for Disease Control to announce last month that it will launch a formal investigation of the condition. If nothing else, this will increase the amount of research into Morgellons. It may even produce some answers.

Bransfield predicts that the medical establishment will soon come to view Morgellons as a genuine disease. "Whenever a disease is unknown, it is often considered delusional. It is only when you have a clear, solid explanation that people recognise the physical basis to it. You see this with any emerging disease throughout history."

In the meantime, many sufferers just wait and hope. "I've taken it as far as I can with doctors," says Jones. "None of them want to know. They just look at you as if you are off your trolley."

*These names have been changed
Daniel Elkan is a freelance writer based in London
From issue 2621 of New Scientist magazine, 12 September 2007, page 46-49
 
A dish full of rat brain learns how to fly an aeroplane

http://www.youtube.com/watch?v=0jeV77dSyMI

An array of rat brain cells has successfully flown a virtual F-22 fighter jet.
...

Enzymes were used to extract neurons from the motor cortex of mature rat embryos and cells were then seeded onto a grid of gold electrodes patterned on a glass Petri dish. The cells grew microscopic interconnections, turning them into a “live computation device”

...

DeMarse’s array of 25,000 interconnected neurons were able to convert signals that indicated whether the simulated plane is experiencing stable conditions or hurricanes into a measurement of whether the plane is flying straight or tilted and then correct the flight path by transmitting signals to the airplane’s controls.

Here is a more in-depth paper on the process involed in hooking up and training a bunch of brain cells: http://www.bme.ufl.edu/documents/the_neurally_10.pdf
 
There was a pretty funny letter in New Scientist lately. It outlined a theory for the fact that intelligent life reaches a certain point in which in the search for an experiment to show the Big Bang it triggers an implosion of the universe and thus resets everything. Thus the CERN is the furthest we can ever get.
 
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