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The Big & Dandy Methoxetamine / MXE Thread - Holey Shit no. 15

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I find that MXE combines incredibly well with every psychedelic I've tried it with. I wouldn't go too high on it, just stick to low to moderate doses of MXE with normal doses of psychedelics.

I agree that MXE pairs quite well with the likes of LSD, 4-AcO-DMT, DOC, βK-2C-B, and 6-MAPB. I also agree with Xorkoth's dosing recommendations. I haven't noticed much, if any, potentiation or synergy, but the two states of mind seem to complement each other quite nicely; of course, YMMV so always start low (and if you plan on redosing MXE it's always a good idea to have all of your doses measured out beforehand). Too much MXE, in my experience, overshadows the psychedelic; again, YMMV.

My preferred time to add the MXE is near the end or after the psychedelic peak, but many seem to advocate leading into the psychedelic trip with an entry dose of MXE so to each their own. I'm purely speculating at this point, but I think the combination of the novel dissociative MXM (aka e-MXE, aka methoxmetamine, aka 3-MeO-2'-OxO-PCM) might be capable of providing more of those potentiating, synergistic effects often reported with ketamine and like those I once loved from combining DXM and LSD. Like I said, though, I have no anecdotal or scientific evidence to back up that claim, so tread with caution in that realm (if I or another don't tread there for you first).

Getting off topic, but on the subject of leading into the psychedelic experience by starting off with another drug, I recently found this quote from PiHKAL #122 MEM (emphasis my own) to be rather interesting:

PiHKAL #122 MEM said:
Many of the reports of MEM effects have been with experiments in which an effective dose of MDMA had been taken shortly earlier. There has developed a concept, embraced by a number of researchers, that the ease and quietness usually seen with the development of the MDMA experience can mitigate some of the physically disturbing symptoms sometimes seen with other psychedelics. This may be partly due to a familiar entry into a altered place, and partly due to a lessening of dosage usually required for full effects. MEM seems to have had more trials using this combination than many of the other psychedelic drugs.

This seems to be contrary to the general wisdom of contemporary drug culture, but I'm sure that very few of us are working with substances so positively identified, of such known purity, in such accurately and precisely measured amounts, in such controlled environments, with as much maturity and responsibility as the good doctor. While I have yet to experience that effect with either an SRA like MDMA or a dissociative like MXE (perhaps due to limited trials attempting such a combination), I could see Shuglin's logic above also applying to MXE in the right dose and setting. Food for thought. Nomnom on it. :sus:
 
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I like adding MXE at either end of the psychedelic, either before taking it or after the peak... if you take it before, it provides a smooth launching pad and the psychedelic come-up is basically eliminated
 
I just did 2mg of etizolam and then 20mg of MXE orally... Should I expect anything? I dumped it under my tongue at first but it didn't stay lol.

I haven't had MXE since back in 2012 or any psychoactive besides alcohol and benzos so I'm taking it slow.
 
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Roughly 100ug of lsd(me) and a half gram of mxe(between me and my girl) made for a hell of a night at the casino/hotel.

I couldn't tell if we where winning or losing, the machines where so confusing. And the hotel room completely changed at least a dozen times. The pool and hot tub where beyond amazing with their color changing lights. The sauna was a bit much though.
 
Wow this is definitely active... Euphoric as all hell... some slight pattern shift and I feel mild dissociation (the "pretzel" effect that DXM gives me" and things just got a lot more depth to them... like the text box looks like a window frame...Eyes closed temporarily and tthere's definite patterns.

Wow. I can't believe I was ever so arrogant as to dump out lines of this stuff and sniff it like it was ketamine... *hangs head in shame*
 
Wow this is definitely active... Euphoric as all hell... some slight pattern shift and I feel mild dissociation (the "pretzel" effect that DXM gives me" and things just got a lot more depth to them... like the text box looks like a window frame...Eyes closed temporarily and tthere's definite patterns.

Wow. I can't believe I was ever so arrogant as to dump out lines of this stuff and sniff it like it was ketamine... *hangs head in shame*
That's what you get wasting good MXE on nasal passages!;)
 
I just did 2mg of etizolam and then 20mg of MXE orally... Should I expect anything?

Isn't 2mg Etizolam too much? I mean not so far in the past I used to use Etizolam to stop MXE trip and go to sleep. And it effectively removed not only residual stimulation but most of dissociative effects. I thought benzo + diss wouldn't be very good, but..:

Wow this is definitely active... Euphoric as all hell... some slight pattern shift and I feel mild dissociation (the "pretzel" effect that DXM gives me" and things just got a lot more depth to them... like the text box looks like a window frame...Eyes closed temporarily and tthere's definite patterns.

Wow. I can't believe I was ever so arrogant as to dump out lines of this stuff and sniff it like it was ketamine... *hangs head in shame*

Glad you liked it :) I will probably try it too soon.
 
Well I always have benzos in my system, I'm prescribed diazepam for anxiety, and I am able to abuse the hell out of MXE just the same. For someone that isn't benzo tolerant it may kill it? I don't know...

What's the timeline on coming up on this stuff? I dropped another 22mg... Mild OEVs and that's with the light on.

I just realized I have to go to the eye doctor at 3PM for him to check my infection and I'm tripping lol.

What is generally a good oral dose?

I'll be honest when I got MXE back in 2011 I just made lines and didn't even weigh them. I loved the high. It was very much like DXM with less dysphoria and no tachycardia is the best way I could describe it but its effects on my speech were fifty times worse than DXM which I could actually stumble through.

Oh this white sandy stuff is definitely nice.
 
What's the timeline on coming up on this stuff?
I agree with Erowid that somewhere around 15-30 mins. And on T+60 mins you definitely will reach plateau.

What is generally a good oral dose?
Can't help with this question, someone more experienced with low dosing should answer. I used it at 50 mg but I guess it more like "high" dose than "common". Anyway it depends on what you call "good dose" :) If you are feeling good on ~20 mg, than I don't see a need to push it higher - because higher dosage could lack of euphoria but would give more dissociation.
 
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I'd say 20-25mg is a pretty "normal" dose for me... If I move up to 30-40 mg from t+60 to t+120 I get pretty scrambled, 50mg and higher is a "full dose". On 50mg I find it very hard not to go into a hole. Dissociation is too intense for me to really still do things actively (unless there's other people tripping with me, this seems to keep you plugged into reality a bit more), so I lie down and trip away xD.
 
lol well this Flubroalpradiazemethoxtizolam (bonus points if you can figure out all the drugs in there) combo that I seem to have done has proven quite entertaining for the night at least.

I've had Mercury retrograde issues too so I've been having communications get all screwed up, PGP broke, and honestly I just want to burst out laughing at the absurdity of the events that built up to this night but the roommate is sleeping and he would not be as amused as I am.

I underestimated two things - etizolam and MXE.

I'm having some mild OEVs even and I don't remember getting OEV patterns with MXE, it was a cold euphoria that needed to be chilled the hell out... MXE was always like that guy that comes over to your house that you dread because he sticks around for a long time and he's odd and he messes with things he shouldn't but you put up with because he gives you a little bit of pleasure in all that chaos.

I don't know what happened this time... but I am much more fond of MXE now than I was before and he can bring his sloppy self around anytime... Just next time I need someone to play with. In every sense of the word
 
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I totally get that. I have tried a few insufflated doses amounting to around 40mg, had me walking a little sloppy, gave a bit of a psychedelic headspace, bit of a mood boost, nothing more. Will try oral soon, to see if that will make a difference.
 
MXE was always like that guy that comes over to your house that you dread because he sticks around for a long time and he's odd and he messes with things he shouldn't but you put up with because he gives you a little bit of pleasure in all that chaos.

HAHAHA, I think you nailed it with that analogy! MXE does take me on an emotional rollercoaster similar to a visit by that guy you described... There's always that bit of the trip where you think "oh jesus, why did I take this shit again? Never again." usually followed shortly "Mmmmmmm, mexxy, mixxy mxeness. This is hilariously great!"
 
What he^ said,
finally got my mix right, I think, each ml of IM sol is 4mg 3-meo-pcp/20mg MXE...seems about right....right?
GF smoked herb w/her MXE, dose and was a bit ...distressed? last night. Swore off the shit, but...she's ok now though. She doesn't do the PCP.
Herb and MXE is a freaky combo...gonna try it again soon, but not her.
 
Yeah marijuana makes MXE SO MUCH stronger, I've gone overboard with just a couple of hits. Usually if I'm not peaking I'll smoke a hit at a time if it's around and I'm good as long as I'm not maxing out my MXE dose.

lol well this Flubroalpradiazemethoxtizolam (bonus points if you can figure out all the drugs in there) combo that I seem to have done has proven quite entertaining for the night at least.

I've had Mercury retrograde issues too so I've been having communications get all screwed up, PGP broke, and honestly I just want to burst out laughing at the absurdity of the events that built up to this night but the roommate is sleeping and he would not be as amused as I am.

I underestimated two things - etizolam and MXE.

I'm having some mild OEVs even and I don't remember getting OEV patterns with MXE, it was a cold euphoria that needed to be chilled the hell out... MXE was always like that guy that comes over to your house that you dread because he sticks around for a long time and he's odd and he messes with things he shouldn't but you put up with because he gives you a little bit of pleasure in all that chaos.

I don't know what happened this time... but I am much more fond of MXE now than I was before and he can bring his sloppy self around anytime... Just next time I need someone to play with. In every sense of the word

It's because you did it orally. It's just so much better orally than any other ROA (well, plugged is awesome but MUCH more anesthetic), it lasts the longest and it's the smoothest and most euphoric. I also get much greater mental effects than nasal dosing, as well as more pleasant dissociative effects.

I usually start with 20-25mg, and then once I hit the peak at 45 minutes or the plateau at an hour or so, I add 10-25mg, depending on where I want to go. I usually don't go to more than 50 or 60mg in total for the night. The first 25mg is very nice, euphoric, slightly dissociating. I sometimes stay there, but if I add the second dose it starts to get more intense and psychedelic, and I get some MXE-walking (I don't say robo-walking because for me it's different than that, I remain very balanced and physically capable but it feels so much different and I look funny walking, yet I can still jump around and do agile things).
 
^I also get an MXE walk hahah, it's like... I just kinda shuffle my feet forward and my body kinda rotates, but I don't really pick my feet up much, and I feel as if I'm kinda leaning back and my feet just move my body without me telling them to... Idk, it's just weird hahah. I'm sure I look silly as hell to sober people. It's almost as if I'm waddling, but much more precise movements.
 
I get this weird dichotomy where I move carefully and awkwardly, but I can still jump around and do physical feats like climbing and dancing. In fact I can jump measurably higher, every time I'm over at my most common MXE-dosing location, I do this test. When I'm not on MXE I have a hard time barely reaching this ledge about 10 feet up, but when I'm on MXE, I can jump and grab it and pull myself up easily, with room to spare, from a standstill.
 
I totally get that. I have tried a few insufflated doses amounting to around 40mg, had me walking a little sloppy, gave a bit of a psychedelic headspace, bit of a mood boost, nothing more. Will try oral soon, to see if that will make a difference.

Woah man, you must have a tolerance like no other! I did the first 10mg of my first batch in a while yesterday and achieved almost those same effects!
 
I never get a lot out of snorting MXE, but 40mg orally all at once would be more than I'd want to go. I'll do 50mg in a night easy, but it's in 2 or 3 doses separated by 45 minutes to an hour.
 
Okay so I feel a little bit better knowing that others know what I was going through this morning.

Next time I'll do it without the etizolam. This was not a planned experience... But it was still a good one.

I think I'm going to get some 4-HO-MET with my next flubro order and try MXE and 4-HO-MET together... I bet that's a spectacular lightshow.

Weirdly I don't have any anxiety or anything... And I did a lot of stuff yesterday. I don't even have rebound from the 1mg of alp I did and alp ALWAYS rebounded for me.

Now of course I am not certain how much I ended up taking so I just said I maxed at 100 but I think it was more like 60. Its not that I wasn't using the scale, its that I was kind of sort of really messed up.
 
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