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RCs The AH-7921 Side effect and withdrawal WARNING

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Bluelighter
Joined
Oct 29, 2012
Messages
668
I not sure if this thread is better on its own or in AH-7921 Megathread so Ill let a mod decide where its better.

So basically Im going to share my experience with this specific chemical and this thread is for anyone who is planing to use AH-7921 for a long period.
First here is the AH-7921 Megathread link: http://www.bluelight.ru/vb/threads/612116-The-AH-7921-(Ah7921)-Megathread-(v1)?

The first part is going to be about the Side effect.
Here is the link to my thread about those side effect : http://www.bluelight.ru/vb/threads/684980-Im-scared-AH-7921-might-be-toxic?

Possible side effect:

- Irritability (common with opioids)
- Feeling dissociated (probably cause by AH-7921 having affinity for ĸappa opioid receptor) <- this is not proven
- Getting half of your hand numb (little and ring finger) [Possible dangerous effect on Ulnar nerve]
- Insomnia (cause by certain side effect)
- Shakes and twitch (less common)

Here is the bigger part of the thread: THE WITHDRAWAL (the most important part is the last one but its good to read it all)

I never withdrawn from any other opioids then Kratom so I cant tell if AH-7921 is worst but because of my experience and knowledge on the subjet I believe AH-7921 have one of the worst withdrawal symptoms because it has a MUCH longer half-life and is quiet strong, I believe it have a good BA (Bioavailability).

I first used AH-7921 many months ago, I bought 1 or 2 grams, im not sure, probably 2. So I usually snort the substance because I dont like the effect of oral route (too much drowsiness and dissociation). I was snorting about 15-25mg 4-5 time a day and after 3 weeks I believe the 2 grams were all consumed. I first didnt knew I was withdrawing, I was feeling very depressed and had mild insomnia. I first thought it was side effect of the Quetiapine (Seroquel) I was taking for insomnia but it wasnt ! A few days ago I was feeling amazing and I understood what was going on. It was the withdrawal.

The second time I bought AH-7921 a few months after that, I bought 5 grams of it. I consumed all of it intranasally in the time of over 1 month. I then thought, the first withdrawal was not that bad... I will be able to pass over this one too. I was wrong ! ... The first sign of the withdrawal was the runny nose, I always get this first and then the game began. Big spasms and twitchs, insomnia, hot and cold flashes, horrible body sensation, it been very hard to past over it. So guess what, on day 2 I bought 10 grams of AH-7921. I had those symptoms for 5 days and then I though : POPPY SEEDS TEA ! I took a 150g infusion of poppy seeds and most of the symptom were gone.

The last part Is when I received the 10 grams of AH-7921 which I received a few days after the poppy seed tea. I restarted snorting AH-7921 but now, 25-35mg 5-6 time a day. After 2 months nothing was left. And I though: damn the withdrawal will be horrible... so I order some Tapentadol before running out of it. The Tapentadol arrived the day after I had my last dose. The even of the same days I stopped using AH-7921 I already got severe symptoms because I was tappering very low because the Tapentadol was not arriving on time. I tried the poppy seeds tea but I vomit it all after supper. I had all the same withdrawal symptom of the second use during that night and then the day after passing all the night not sleeping I had to wait until 13h pm to go get my Tapentadol at the post office. I past most of this time driving around listing to music which made me cry and this music doesnt make me cry normally... its Eminem so obviously there is no other reason to cry then the withdrawal.

That day I started snorting Tapentadol (very painful) and it never relieved any symptom, I dont know if it was because I was in acute withdrawal or because Tapentadol is weak but It simply didnt worked. In the evening I started vomiting HARD. Every piece of food every ml of liquid I was putting In my stomach I vomit it severely for minutes, even if there was nothing in my stomach I was still vomiting, There was lots of blood and bile in it all the time. The evening I vomited 5 time and then I deceided to go to the Emergency at the hospital where I had to tell my storie. During the waiting I had severe agitation, I hyperventilated, all my body became numb, I had spasm and twitchs. They finally treat me by injecting me 5mg of morphine. Most of the symptom were gone after that so they prescribed my 5mg morphine oral. It worked for a day then I started vomiting again I returned to the hospital but I was taking too much time and I started feeling better so I left the hospital before seeing a doctor. I past 2 other days without vomithing and then It started again. I returned to the hospital and now I waited a long time and the day after I finally saw a doctor which prescribed me Ondansetron to stop the vomiting.

Im now taking the Morphine and Ondansetron and my condition have stabilized. Some food give me nausea but I dont vomit. I believe that even if im on morphine 5mg oral which is a rediculous dose compare to the dose of AH-7921 I was taking, I think I might be on PAWS (post acute withdrawal symptom) for now because I only suffer extreme depression and im very weak.

During this event, I couldnt eat during 6 days and I lost over 10 pounds.

After going throught this episode and being treat at the hospital I will now try to stay away from any drugs especially Research chemicals.

If anyone have question or need tips, I may help. If your going throught what I went throught, I feel your pain and I urge you to see a doctor.
 
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Damn that's quite the story. I'm surprised they shot you up with morphine and have you take home, that's kinda awesome.

If I wasn't already in treatment I might have considered buying this stuff but meh. Hopefully you truly are done if not I'd really consider not using new RC opiates but stick with traditional, normally I'd never advise anyone to do so but at least they have been abused for 100+ years.
 
Wow, glad you are feeling better now but you have to admit that you binged really hard on it. I mean 10 Grams(!) in 2 months? Holy shit.
Nobody knows the real potency of this stuff.
Also your assumption of a good BA is not the case. AH-7921 has a pretty low oral bioavailability.

I only used about 250-500mgs of this with some breaks in between and never experienced any worrying symptoms, only the numb hand thing happened to me twice.
 
I know right, I really abused it hard. About the BA, I dont know... when I tried it orally I always get overwhelming effect like too much drowsiness, constant unplesant nodding, feeling very dissociated and I only took about 50mg. Do you think intranasal BA is higher ? I get really good effect from snorting it. I only get very dizzy if I redose to much in a small amount of time. But yeah we cant really know the BA, no studies have been done on it but 5mg intranasally is much more potent than 5mg morphine oral.
 
I started vomiting again... I vomited bile during 1h with breaks in between... Can I take 2 4mg Ondansetron ? Will it help ?
Thanks
 
Sorry to hear about all this. Sometimes people need to learn moderation with their drug usage the hard way, so I at least your ordeal isn't all in vain.

On another note, it seemed like BLers were pretty worried about the potential harms of these RC opiates being mass-marketed. But frankly I'm just glad the ones out there so far don't sound necessarily too enjoyable.
 
I haven't used as much as you and haven't gotten any withdrawls but I've gotten the numb hand effect. If you don't use your arms for a while like say you're laying down watching a movie on a laptop or something It always effects my right hand going up to my mid for arm, it feels like you fell asleep on it or something and then have to get up a shake it around to get the feeling back. I kind of like the ever so slight dissociative part about it, it gives it its own unique flavor. Do you think it could be the back of your throat that is bleeding? Because that happened to me the 2nd day in a row that I was using it IN. Its absolute hell on your nose and back of your throat but the most effective way to use it if you don't use needles, but after about the 2nd day of snorting it the back of my throat pretty torn up and I went to cough up flem and it was all bloody, I did this twice and woke up the next day and spit in the morning and saw that rusty brown color of dried blood in my spit.
 
Do you think it could be the back of your throat that is bleeding?

Definitely not. Everybody talk about how corrosive and painful this chemical is to snort but I believe my nose have "tolerance" to corrosion because I dont even feel anything from snorting it and my nose doesnt bleed.

Im kind of happy to see more people start talking about this numb hand thing I was really starting to think I was the only one suffering this. But it most do something to Ulnar nerve, I dont know what though...
 
Damn working during a withdrawal symptom is the worst thing ever... I even vomited at work and Ondansetron doesnt help that much. I lost 15 pounds since the withdrawal started. I barely eat anything everydays. Im going to see a doctor tomorow... again.
 
Just a last feed back and summary from my experience so the thread can be complete. The last doctor a saw prescribed me Pantoprazole which helped me to eat and drink during the days, though I still had stomach pain and vomited sometime the first week, then I sudently felt great and could eat normally.

So it took about 3 week from the last dose, with 4 visit at the hospital, 6 actually but I left before seeing a doctor 2 time because it was getting too long. The first doctor prescribed me a Morphine taper during 12 days which got rid of those horribly cold turkey symptoms but not the vomiting, the second one prescribed me Ondansetron which didnt do anything for me and cost me half of my paid check. The third one was a clinic doctor so he could not do much else than giving some tips and finally the fourth one was a specialist in toxicomania and prescribed me Pantoprazole which really helped me with that horrible sickness I had.

The last doctor and I believe that all that vomiting and stomach pain were cause by too much vomiting which is pretty much a vicious circle.

So now I feel great, I eat plenty of food and gain some weight back.

Conclusion : Do not take AH-7921 on long term and above all, do not quit cold turkey with this drug you gonna get your self into SERIOUS trouble.

BTW im sorry for the mutiple post but I believe this is important.
 
Thanks for the update. How's your legs and feet doing? I know you said last week your big toes were still numb. Do you attribute this as a side effect of ah-7921 like your hands? I'm glad you're feeling better now!
 
The last 2 days at work, my legs did hurt less then the 2 first day of the week, though my back was hurting more. Im on weekend since the 3 last days and Im going to work tomorow so Ill see for that.
My toes are still numb, im not sure if its related to AH-7921, it might be the first pair of boots that was hurting my feet bad that I wore for a week but I thought it would be gone by now, meaby it was the combination of the AH and the boots, meaby its something else, I have no idea, my doctor will help me find out when Ill see him.
Thanks !
 
On another note, it seemed like BLers were pretty worried about the potential harms of these RC opiates being mass-marketed. But frankly I'm just glad the ones out there so far don't sound necessarily too enjoyable.

odt was fuckin wonderful. But it seems there was only ever 2 batches of it made commercially available. Word was begininning to spread towards the end of the second batch, and before a 3rd batch could be produced it was banned !!
 
Because I've been on second long term trip on AH-7921 after getting fired from my job for no obvious reason, I got drunk that night and ordered 20g of AH-7921 which was consumed during 3½ months. I now have clearer view of the side effect of AH-7921. So im making this new side effect profil of it.

First of, the first side effect that comes when consuming the drug is extrem dryness of eyes, nose, month and skin. If AH-7921 is consumed during the evening or before night, I wake up multiple time for that reason, I need to put clear eyes in my eyes to get some liquid on my eyes because they are completely dry and hurt bad. For the nose I use Xylomethazoline or Oxymthazoline nose spray to get it moist and get rid of the extra mucus. For the mouth I use a mouth hydrating solution called Biotene.

The dry skin also get bad rash over time, red irritation and irruption. This only got cured by a prescription ointment containing Ketoconazole and Cortisone.

Then the numb hand happaning during the night, half of the hand; little and ring finger get completely numb, this look like a blood circulation problem that like eyes and ect get dry, it feels like body fluids ticken including blood causing blood circulation problem. I also get this in my legs in high doses. The problem can be temporarily reverse by shaking hand or legs.

Dissociation can be a problem sometime while some people report liking the effect. Its probably AH-7921 having ĸappa affinity. After digging a little I found some analogues or related molecules that are powerful ĸappa agonist so this theory look pretty possible.
AH-7921
AH-7921_structure.png

BRL-52537
BRL-52537_structure.png

GR-89696
GR-89696_structure.png

ICI-199,441
ICI-199441_structure.png

ICI-204,448
ICI-204448_structure.png

LPK-26
LPK-26_structure.png

U-50488
U-50488.png


A typical opioid side effect is constipation but AH-7921 cause blood in stool so probably bowel damage.

Then the withdrawal. My first severe withdrawal is discribe in the first post and was pretty intense. This time I've been tappering and this greatly reduce the symptoms though one symptoms persists and I believe is unique to AH-7921. Very bad acid production in the stomach. For some reason while I am taking AH-7921 I dont get acid problem but when I quit, acid become very bad and I bear can eat during this period because it makes me vomit all the time. The first time the problem have been cured by the prescription Proton-pump inhibitor; Pentoprazole and completly got rid of the problem. This time I didnt see no doctor so I could get hand on some Pantoprazole so I took the commonly used Ranitidine acid reducer. It is a H2 antagonist. Its not as good as Pentoprazole but it did help me eat during the harder time of the withdrawal.

So this is it for my new more detailed side effect post.
 
Honestly why fuck with such an unknown opioid when heroin is cheap and readily available? I would get off that shit and onto a more traditional opioid ASAP if that's how it's going to be
 
Cause I dont have acces to any opiate I dont know any dealers other than RCs vendors and anyway Id like to quit drug to be honest.
 
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Honestly why fuck with such an unknown opioid when heroin is cheap and readily available? I would get off that shit and onto a more traditional opioid ASAP if that's how it's going to be

Maybe in the states it is...globally "cheap and available"? Certainly not.
 
I don't have any opiate tolerance. I've used 500 mg's of ah7921 and an op oxy 80mg over the past four days. Do u guys think I will experience withdrawals?
 
AH-7921 is poison, to be honest everyone should stop using this substance for now on. I got a very severe gastritis that lasted almost 2 months and lost 20 pounds cause I was vomiting everything I was eating. The withdrawal only lasted 3-4 weeks and the gastritis last for ever. I getting better but its not even over yet.

Hospital said I have laceration to liver and severe irritation to stomach after passing an endoscopy and an ultrasound.

I been the guinea pig for you guys, I hope you take my words and stop using AH-7921 forever.
 
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