As far as cortisol is concerned, I have known high cortisol levels documented through testing. So, that could be a factor.
@Swim15
does anyone report differences in energy levels and/or sex drive, sexual function with magic vs meh MDMA?
Yes. Definitely. It has been discussed at length in the other thread.
For me personally, "magic" MDMA produces unbelievable sex. There is a strong sex drive, and the sex can go on forever. The "Meh" product just does not hit the same way. Does not put me in the same physical/sexual space. Way less energy and drive. I'm female, so, I am not talking about erection, but general arousal. It is an obvious difference between the two products. Also related, with magic stuff I just want to touch, touch, touch my hair, my skin, other people's hair and skin, clothes, wallpaper, bedsheets, blankets, pets...you name it. Texture is enhanced because touch is enhanced and I want to rub everything. Not so with the "meh" product. I don't want to touch or rub anything because nothing FEELS any different.
As for energy levels in general, pretty much everyone in the other thread who has noted this phenomenon agrees that magic product creates a more energetic experience and the meh product almost immobilizes you. Also, magic is more talkative and the meh product makes you not want to talk.
5HT to DA release based on some ambiguous factors I’ve observed but hard to tell.
Funny you mention that, because there is a study that went into detail regarding inhibition of monoamine transporters due to certain synthesis byproducts:
https://sci-hub.tw/https://doi.org/10.1124/jpet.105.084426
One of the byproducts suppressed MDMA release. "The potency of 13 in its inhibitory action on MDMA induced release was in agreement with its potency in uptake inhibition experiments: 13 suppressed MDMA-induced release mediated by the SERT more potently than NET-mediated release, whereas MDMA-induced release mediated by the DAT was only weakly inhibited in concentrations up to 100 uM" (p. 350).