I can't remember the doses of the buproprion pills. I think they were 150mg extended release ones? If so, I use to snort up to 2-4 of them a day to keep myself going. It was usually in the 300mg+ area where side effects would show up. Usually the auditory hallucinations lasted a few hours. Some times the rest of the day until I took a benzo and went to bed. They were similar to the hallucinations I get from sleep deprivation on meth binges. Except I didn't feel spun out on it and these had a tin-can and flanging effect to them which I thought was peculiar.
Sounds anticholinergic I'd say.. weird that I used 20x 150mg in one single day without getting either hallucinations nor flanging or seizures. Only side effect of it is inner tension and tinnitus, the latter weirdly enough not present upon insufflation. But I also got nothing besides a weird physical sensation when I tried 500mg diphenhydramine - maybe thankfully so. Delirants aren't to mess with. Love to read trip reports though of angels trumpet et.al.
I also tried venlafaxine in my 30's again & it was not as good as in my 20's. In fact all it did this time around was make me fee weird and nauseous. So I stopped that again as well.
Oh that's interesting for sure, just that I'd add that in the teens stuff was
even more euphoric than it was in my twens and now as 30+ I only take antidepressants because my body is addicted to them. Many drugs including DXM, venlafaxine, paroxetine, bupropion, ketamine were different in an earlier age. I always thought it must be tolerance because that's what most people say but I'm not convinced. At least not tolerance in the usual sense. Did you read about the 50 trip limit with DXM (I gout more than 50 trips but the number might fit with higher dose use, Idk, but it seems to related to age).
Somehow I got curious about mTOR activation by dissociatives, this circuit seems to be involved in both K's rapid antidepressantivity as well as aging. Just I don't know whether the activation does actually ageing or anti-ageing. Makes an interesting thought play tho, tripping against anxiety (serotonergic psychs might do the same for the mind but as I'm hooked on SSRIs I can't trip).
Velafaxine and tramadol definitely share chemical stucture, but unfortunately I found the two incredibly different from one another.
Tramadol also weakly releases serotonin which would make it a fast acting AD. I was in love with tramadol for 10 years. Around the 400mg range and I was a happy camper. Hoped venlafaxine would feel similar, especially with bupe, but was highly disappointed.
For me they're similar in the sense of creating a similar withdrawal. Tramadol is a releaser, yeah while venlafaxine is a reuptake inhibitor but I believe it's a releaser as well given that venla worked for me but tramadol didn never its job, only the purified metabolite O-dsmt was nice. Tianeptine works for me. with 100mg+ it creates a serotonergic-opioid-like high but only briefly so, duration is maybe 1.5h while the sulfate (which I never tried yet) might last 4h or so. It seems to be the only opioid which doesn't suppress respiration if I'm correct.
I felt that shit like it was modinafil, for me. Not a great feeling for someone with horrendous panic attacks.
Yeah, there is some similarity to modafinil indeed. Bupropion only shines when combined with DXM, they even have this combo in approval process. Was the most stimulating drug I ever tried this way, more physically stimulating than DXM+methylphenidate which is on 2nd place and meth+memantine which might be place 3. Meth is more in the head while bupropion+DXM is a physical beast. Just that with 20y/o it worked beautifully while now with 35 I only got side effects, I guess related to the DXM which somehow catalyzed bupropion but while I loved it as a teen, now it's a full blown psychotomimetic as in hearing voices.
Will never understand how one can like modafinil. It's not scheduled here for a reason. Similar to too much caffeine. Seems to work for narcolepsy but that's it. Some seem to get similar focus like phenethylamines, I wonder what's making the difference..
Just wonder how the phuck they passed tianeptine, I'd bet animals would self-administer it.