Blasphemous Confessions of an Other Drug's Moderator
Ok, I know the commonly accepted verdict on this whole fiasco is that loperamide does not cross the blood brain barrier (BBB) thus no central nervous system (CNS) activity thus no high.
Well, I am here to say, something doesn't sit right.
I know I'm probably putting what little respect and credibility I have on the line right now, but I don't care. If this can help anyone in who finds themselves in my current situation, then I feel I should share.
For the last week, I have been aiding my Suboxone withdrawals with Loperamide (Imodium brand). The first day, I stuck to your typical, box-suggested doses. All it did was keep me from shitting.
The next day, I upped the dose by about 50mg, for a grand total of 60mg.
An hour later, the first hints of, we will call it, "opiate like intoxication," became noticeable. By this, I mean dry, tired, scratchy eyes. Lowered blood pressure. Relaxed breathing. Reduced anxiety. And best of all, the most wonderful and beneficial aspect of high-dose Loperamide, reduced (read: completely gone) joint pain and the stopping of the "skin crawls."
It's wonderful. I went into this experiment thinking, "Ok, I'm about to waste 12 dollars, but I'm intrigued enough to try." I came out of the experiment thinking "I'm going to do this again."
Why this happens? I do not know, but there has to be some CNS activity. My theory is that Loperamide is not COMPLETELY blocked by the BBB. There has to be a small amount that can make it through, thus CNS activity in high doses. The higher the dose, the more that gets through.
I have made it a week now without Suboxone, heroin, methadone, any opiate at all, besides Loperamide. It works wonders for the reduction/elimination of withdrawal symptoms. I can't say that it's getting me high, but to someone in withdrawals, feeling normal is a high in-and-of itself.
So, if you are withdrawing and can't get any other drug for relief, or if you don't want another drug (to get fully clean), then pick up some Loperamide. I've been taking anywhere from 40 - 60mg every other day and it's great.