we need to figure out the most effective way to do this, if its even true. apparently having loperamide crossing the BBB IS POSSIBLE but what worries me is, if its as potent as fentanyl, or even close, and say you wanna experiment by doing an CWE and administering the [somewhat] pure loperamide either orally, nasally or IV, and you figure, around 30mg might work, so you take it along with GFJ, and then end up waking up in withdrawal from the naloxone injection that was lucky enough to wake you up from your serious OD (imagine 30mg of fentanyl).
But more research has to be done on this nonetheless! with the right info, this could be just as easily abusable as an opiate as dxm is as a dissociative
And before you know it, its in history books 100 years from now, like about how brand name Heroin was sold OTC for morphine addiction, and loperamide, a fentanyl analog was sold otc for diahrrea