Tchort: "Rating 7-hydroxy.": The only figure I would ever used is the one from Chiba, which is the one I quote. People using spurious concotions sold online or in "headshoppes" are not going to be able to determine anything,
Since the plant has no consistent akaloidal percentages you cannot draw averagcontents like you can when dealing with opium. One leaf, or even one part of the same leaf will have greatly varying percentages and so even if there were someone doing an actual extract, as opposed to an A/B, one could not say 10X, 12X, or 50X anything.
It is all nonsensical marketing hyperbole. Same as lableing it "Thai, Bali," or whatever. It is grown in all of two places commercialy and people are believing they are getting different strains (there are NO strains).
It saddens me when I see anything being misrepresented like that, especially when I have a vested interest in the plant and dishonest represenation could cost me an arm and leg financially.
On a W/D Aid. No, not really. There was one peer reviwed paper, out of NZ where they used subjects from a methadone clinic and I am sure they are a great pool , since methadone has a very pronounced (in terms of duration) physical W/D. The only positive feedback was that it resulted in more vivid dreams but hey, a salami sandwich does the same for me so...
On a personal note, as I said, I have an unlimited amount, etc. As most know I have also had to endure a couple of W/Ds in the last 2 years and so I have of course trued to utilise it but got no psychoactivty NOR any relief from my W/D.
Tangalang: "Rx grade mitragynine.": Well the structure is actually very close to Yohimbe, as most people see on the Erowid pieces. Actually correct info. Closer to Yohimber, psilocybin, and so on. However, no psychaodelic effects have ever been noted either clinically OR (to my knowledge) subjectively from respondents.
Structure unfortunately does not mean anything in terms of a substances classification, and in psychadelic compounds their psychoactive potential since the pharmokinetick aspect is such an unknown. Well let me more explicit, it IS known for MOST to a small degree. We know most of the metabolic processes, most of the physiological responses, but not the lines that would connect the dots. That is the easiest way to describe it.
I should add though, when that garbage was distributed AS Kratom (the Mynammar AKA Burma materiel that was sold by a French expat a few years ago there were reports of "shimmering" but that was about it so perhaps there avenues to exolore in the mitragyna family. I know myself that I want to isolate a few specimins of Janaica which I am sure is growing wild here. I could spend my literal lifetime catalouging plants that grow on our various properties (wild plants) and still never come close to finishing...but I intened to go out and specifically search for Javanica.
Should be rather easy actually. The mytragyna family require very specific mediums.
Soulcheez: The paper you linked to was the one I mentioned all through the thread, as well as Tchort mentioning it spearately several posts ago. Most wwork on the plant is being performed by that team. The facility is the Pharmo Dept of Chiba U in Japan.
Colmes: "Do you have any citations?" Yep, just mentioned it. Tchort though quoted the exact citation when he noted it rated at 1071% (i.e. 17X).
As I have said several times in this thread (and probably hundreds of times over the years oin this forum) it IS 17X that of morphine, but only in analgesia although that is used as a general barometer for psychoactivity. As well I have also explained that it is only ever present at less than 1% and most times much less than that. This is why it does nothing for anyone but opiatenaive.
