I got some pretty fucked up auditory hallucinations, and a large ass amount of macropsia on 400mg dihydrocodeine, inanimate objects were talking to me and shit like that.
Funny you should post this topic though, as I was just reading of an analogue of salvinorin-A that caught my eye, and one day, as soon as I have the facilities to safely handle the chloromethyl methyl ether that is required in the synthesis, I intend to synthesize it.
This analogue, apparently has 7x the potency of salvinorin-A itself, and is also a mu-agonist, so its primarily a kappa-opiate agonist psychedelic in purpose, with secondary mu-agonist effects, rather than the other way round as is usual.
I want to find out the strength of the mu-agonism and how tightly it binds to the mu-receptors first though, before I attempt the synthesis, because something that potent as a kappa agonist, would be active at an incredibly low dosage perhaps even lower than LSD (I calculated threshold dosage from salvinorin A at 200mcg, that would give threshold dose of the analogue at 25mcg)
However, I am absolutely bleeding useless at math, so don't blame me if I am out by 100mcg or so!
F&B, I had a bit of an idea, is the O-demethylated DXM actually a mu-agonist? what about demethylation with pyridine, that might actually turn DXM into something that is more than worthless, stomach turning, projectile-bile-launching filth
If all it needed was a bit of pyridine, an properly dissociative mu-opioid agonist sounds like good times, so help a bee out, and PM us if you know anything more about it