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Efexor (effexor, veniafaxine) - full on phenethylamine

I've been on venlafaxine for years, usually at 150mg (used to be 225mg, but I thought that it wasn't really any more effective at the higher dose). I'm not even sure that I am benefiting from them anymore, as I have recently started to break through my lifelong depression and anhedonia thanks to LSD. Even though I can't be certain that venlafaxine is really doing anything anymore, I don't really want to stop it. I've been through SSRI withdrawal (from sertraline, which kind of pooped out for me after a while) before and it sucked ass--left me with dizziness, nausea and temperature dysregulation for almost a month. So I suppose even if the venlafaxine is more of a placebo than anything else by now, it is better than wanting to puke for a month.
 
Madmike said:
Self-diagnosis.

Yeah the anxiety get's whole lot worse when I don't take care that I eat regularly.

I feel that sometimes I can't do anything right.
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The really weird thing is that back before I was diagnosed with panic-disorder and OCD, I too self diagnosed myself with hypoglycemia. I thought since I had all the classical symptoms of hypoglycemia, it was clearly what I was suffering from. I went to the doctor the next day who took a blood sugar test which confirmed my blood sugar levels were perfectly normal. I was actually just having a panic attack (the symptoms of which might resemble hypoglycemia).

I found that I would jump to conclusions as to what medical condition was wrong with me, and it took a year for me to finally accept that I just had panic disorder and OCD and what I was suffering from was only anxiety.

Best of luck to you. The earlier you get diagnosed with a form of anxiety and get proper medication for it, the earlier things will get better.

_ _ _ _ _

Good news! I was put back on effexor today. I am to stop taking 20mg daily of paxil and to switch over to 75mg daily of effexor. I took the 75mg 2 hours ago and I already feel MUCH better. Bitter-sweet noradrenaline stimulation!
 
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Some people do get the euphoria and stimulation from taking venlafaxin. I am one of them. The thing is, I only get it from low doses of 37.5mg imediate release. If I take more relaxing effects take over. The e like effects go away after about a week of use.
 
Now that I have been upped to 225 mgs from 150mgs, and stopped drinking alcohol , I can actually feel these cold vibes, like euphoric sensations. I feel like I would be high!

Better not to such high doses, like 300 mgs today, so one doesn't develop tolerance to it's Xtacy like activity.
 
Madmike said:
oh come on

why are you supporting pharmaceutical companies. I must myself stop using 225 mg Efexor a day.

I don't like the drug, it doesn't even work with me anymore. All is just fucked up mess, I don't like my brains can't function normally.
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Why not? It's the only serotogernic AD not causing me side-effects, unlike Paxil and Celexa. I've stopped twice by tapering and the depression has always returned. See i got chronic depression.

But why are you on a such high dose if you dislike it? And what made you to start supporting pharm. companiesin the first place.

What's you're plan from now on if you need an AD? SwitcH to TCAs?
 
Just an idea, no theory

Venlafaxine is a racemic compound. Could be possible that the other enentiomer would bea SRI and the other a NARI?
 
superponce said:
Yo,

I hope this is the right forum, it was either here or 'other drugs', but I am more ione) venlafaxine HCl pills (37.5mg), and I have to say it was quite similar to taking a pill withoutnterested in the pharmacology than anything else...

A few weeks ago, on the pavement, I found four (and took every fully coming up. All in all pretty intense to the point of lying down and breathing hard for some of it. An enormous variety of drugs have passed through my system, but none in the last 6 months and hardly any for a year, so I'm a pretty clean guinea pig. I had had one beer...

Is it just me who has ever had this rather profound effect from this stuff? I could as much imagine taking this daily as eating 80mg of MDMA daily... Can't be good for people.

On looking at the structure, there are (possible) elements of desoxypipradol and pma here, I wonder what desoxyvenlafaxine would be like? As in without the alcohol group??

I have no intention of using it for depression, but once in a blue moon I may take one and go out on the town...
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You are kidding right? They call this drug "Side Effexor" for a reason! Not a pretty pharma to play with......I took as one is supposed to, only at 150mgs.
which is the "normal" dose for most after a few months, I was ready to move people's faces around, which is NOT me! Lots of other nasty side effects too.
And NOT that I'm anywhere CLOSE to a champion for the cause(!), it seems that Andrea Yates, who drowned her children in the tub, was a user of this med, and/or coming of of it. It truly is NO joke. And if you have never had to feel or deal with "brain-shivers", then do yourself a favor, and don't.

With Consideration, Christopher
 
Effexor....

SpunkySkunk347 said:
I'm going back on 150mg effexor shortly (hopefully sometime later this week)

For me, effexor was so effective at alleviating social inhibitions and social anxiety that I would compare it to better than alcohol or even some less-potent stimulants (methylphenidate)

It has been almost a year since the developement of my panic disorder and anxiety disorder, and I can say that most of my anxiety is somehow connected to socialability, and that effexor is a very effective treatment option for me.

The reason I went off of it, is because for most of the duration that I was on it I was in a hypomanic/borderline-manic state. If that is the case this time around, I hopefully will be prescribed some anti-manic type drug to combat this.
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Hi,
If you see this, I would soo very much love to talk to you about this medicine.
Would that be possible?? I've been on it, and I'd like to compare with you it,
and what I'm on now, if you wouldn't mind??
Thanks, Christopher ([email protected])
 
Such high doses...

Madmike said:
Now that I have been upped to 225 mgs from 150mgs, and stopped drinking alcohol , I can actually feel these cold vibes, like euphoric sensations. I feel like I would be high!

Better not to such high doses, like 300 mgs today, so one doesn't develop tolerance to it's Xtacy like activity.
Click to expand...

Here's what I know...and you name it: Prozac, Paxil, Celexa, Effexor(!), and I'm
guessing(?) any other S.S.R.I. drug, it makes a person totally "numb", to any
type of emotional feelings. Tell me this...How in the fuck do you, or does anyone find a "fair" way of staying "in love" with their girlfriends/boyfriends??
Sex is fucked off, and if you say it's not, then you are lying. I just wanna know HOW do we conquer both depression/anxiety, AND the desire to still WANT the desire to be with our loved ones??? Those of you who have been on these drugs, know EXACTLY what I'm talking about. If you haven't been, then do some research first, please?
There is NO Viagra/Cialis pill that helps bring back one's "sensitivity", and it's
honestly killing the best thing I have, or will ever have, with a wonderful woman. If this is too "sensitive" for any of you, forgive me. Personally, it's no
joke, and I truly don't care WHAT anyone thinks. I just want to give and recieve any help that I can get/give. Believe that.

[email protected] Thanks, Christopher
 
Tell me this...How in the fuck do you, or does anyone find a "fair" way of staying "in love" with their girlfriends/boyfriends??
Sex is fucked off, and if you say it's not, then you are lying. I just wanna know HOW do we conquer both depression/anxiety, AND the desire to still WANT the desire to be with our loved ones??? Those of you who have been on these drugs, know EXACTLY what I'm talking about. If you haven't been, then do some research first, please?
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This sort of blanket statement is ridiculous. Lots of people have that experience with this class of drugs but certainly not all. My wife and I have a lover who takes Paxil, he sure doesn't seem to have any problems relating or in bed. He is very happy with the drug.

Will you now accuse us of being liars?

I'm not interested at all in the main argument here, so don't waste time responding as such. I am, in fact, among those who dislike SSRI/SSNI's quite strongly.

But I couldn't help but respond to such a statement.
 
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Florpuskel said:
Some people do get the euphoria and stimulation from taking venlafaxin. I am one of them. The thing is, I only get it from low doses of 37.5mg imediate release. If I take more relaxing effects take over. The e like effects go away after about a week of use.
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Snap! For some reason the sustained release variety do nothing but relax me, they make me feel more like going to sleep!

And as these are easier to take in higher doses, I would also agree with your other statement, ie that the lower doses cause some euphoria and stimulation but that disappears at high doses. Also, it doesn't last and after a day or two of enjoying their effects, I have to have a break before I can achieve this effect again (which is just as well since that's my prescription gone until the next month, normally!) :)
 
Some people do get the euphoria and stimulation from taking venlafaxin. I am one of them. The thing is, I only get it from low doses of 37.5mg imediate release. If I take more relaxing effects take over. The e like effects go away after about a week of use.
Click to expand...
I'll agree with this, but it also depends on having upregulated or normalized adrenergic receptors I think.

I say this because the first time I ever tried venlafaxine I stole 1 blister packet of the drug from a manic schizo dude who wasnt even dosing on the stuff his life was so hectic.

Anyway, I had done alot of speed back in those days (going back over a decade now) and it had little/no effect.

The next time I tried it I was "clean" and it had profound effex for the first few days.
 
i am just adding my personal experience with this substance here, cant really add anything to the theories i guess.

i was on venlafaxine for about 15months. my dosage regimen was 150mg slow-release/day. my diagnose is add and recurring depression and my doctor thought this might help with both problems.

the first pill i took (75mg SR) i also got effects that resembled an mdma-experience quite strongly. but second dose at the next day did not do anything at all in that regard.

in regards to my problems it did wonders for me. all social anxiety was gone quickly, i generally got more lets say mental constitution (means that it needed significantly more distress to make me worried etc) and it stabilized my emotions also quite well. after about two weeks most side effects were gone, only the increased sweating stayed with me longer but also vanished after about half a year. my sexual drive and performance actually improved, but not that much.

but well, as things that work that good almost always have some caveat, after it started working for me my general drug usage increased quite a bit - first i had a phase where i had a very profound cocaine usage, at least for me (i guess i did about 20g in about 5 months) - then i switched over to mostly amphetamine, sometimes mdma. also my alcohol consumption increased a lot, but this i managed to get to the level i used to be at before i started the medication.

when i stopped i went "cold turkey" as i ran out of them and had no cash to pay for a new package, this also happened the day a long weekend because of holidays started (eastern), which seriously limited my options in getting my pills. so i decided that it might be a good time to getting of the stuff (i also stopped my other drug usage completely). it was kind of rough, although not as bad as i expected (i had some experience with withdrawal from times i ran out of them and needed two days to get some new - having no health insurance did not exactly help there ;).

anyway, i am now a bit more then two months of the stuff and i think i am gonna get on it again, mostly because of a new job starting for me and i dont wanna loose it because i am not functioning. (too long of a story to put it in this post)

ah yeah, for the ADD it did not that much i think, maybe a bit.
also i should add that while i was on venlafaxine i also was on mirtazapine 30mg/day (great stuff! :) )

one thing i forgot: as long i was on this stuff mushrooms and LSD almost completely ceased to work for me. with mushrooms i only got some slight annoying buzz (and i am very positive on the potency of the mushrooms i ingested). LSD i only tried once at a, i think, moderate dosage (shared a blotter with a friend, he had effects somewhere between ++ and +++) - maybe a higher dosage would have worked better.
 
Since it is a reuptake inhibitor, that means there must be a release of serotonin/norepinephrine/dopamine FIRST in order for effects to be acheived.

My theory is that the positive effects of this drug must be sought in order to be felt fully. Simply anticipating the positive effects of the drug will trigger the positive effects themselves.
 
formanchristopher said:
Here's what I know...and you name it: Prozac, Paxil, Celexa, Effexor(!), and I'm
guessing(?) any other S.S.R.I. drug, it makes a person totally "numb", to any
type of emotional feelings. Tell me this...How in the fuck do you, or does anyone find a "fair" way of staying "in love" with their girlfriends/boyfriends??
Sex is fucked off, and if you say it's not, then you are lying. I just wanna know HOW do we conquer both depression/anxiety, AND the desire to still WANT the desire to be with our loved ones??? Those of you who have been on these drugs, know EXACTLY what I'm talking about. If you haven't been, then do some research first, please?
There is NO Viagra/Cialis pill that helps bring back one's "sensitivity", and it's
honestly killing the best thing I have, or will ever have, with a wonderful woman. If this is too "sensitive" for any of you, forgive me. Personally, it's no
joke, and I truly don't care WHAT anyone thinks. I just want to give and recieve any help that I can get/give. Believe that.

[email protected] Thanks, Christopher
Click to expand...
Who the hell are you to tell everyone that they have shit sex because they are on Effexor. Sod off.
I have a very healthy sexual appetite thankyou very much. Sex is not "fucked off", and neither is love, quite the contrary.
On topic, I am able to gauge these stimulatory effects far mor closely right now being off of benzos, and indeed small snappy doses provide an evident lift with grinning and mildly enhanced appreciation of music and visual aesthetics. When it fades there is grouchiness. An easy drug to take hardcore drugs on top of definitely, no interactions noted with any stimulants/psychedelics/tranks/opiates etc.
 
Despite the fact that it is probably the best marketed AD on the market, it must be conceeded that venlafaxine is a bit of a 'pussy' drug, no?

In jail they amped my dosage up to 225mg then when I was let out 2 months later I was left to fight it out cold turkey.

Fuck all u bitches who wimp over the WD. Take it like a man!
 
NO!! Big big difference. Can't talk right now, but will explain tomorrow which is today.
 
/\ well, when i am dependent on something it means I cannot do without it. And when I am addicted to something, it also means I cannot do without it.
 
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