Thats a good question? I wonder how the high would compare Desoxyn vs street shards. Maybe impurities would effect high as PQ suggests.
What drug ranks higher in terms of likability and intrinsic acceptability: Adderall or dexedrine. Sometimes different brands of the same drug seem to have peculiarities in efficacy- a pharmacist I know was involved in a study investigating the phenomena for reasons that were unclear (molecular footprints, differences in the synthetic process?) Its not fully understood. I've experienced this personally with different methadone formulations even though differences in subjective effects at equivalent doses is counterintuitive.
In the late 80s/early 90s I got ahold of dexedrine which my friend was being prescribed to his brother. Found the high euphoric and smoother than the penut butter/ purple crank going around at the time. Crank seemed to have more of an enhanced tactile sensation effect than the dexedrine. Euphoria wise the best high I got was from a pharm formulation that by then was almost 15 years old called appetrol. Came in capsules and the powder inside looked like coffee creamer. Was I think 5 mg of dexedrine with a dose of meprobamate. That was very smooth and euphoric but I think the meprobamate was potentiating the euphoria. I think there is some magic to the combo of barbs/amph that synergizes euphoria above and beyond smoothing out side effects. Maybe miltown did this based on a similar MOA to barbs. At any rate 4 pills would make me feel fanfuckintastic. I knew a girl that used to get black beauties in mid 80s that used to say they were better than crank.
The old timer from the first post used to say obetrol and preludin were the best stims. He used to like to take the preludin with placidyl. He had stories ( he grew up in the town of Oceanside, CA) of going down to mexico and comming back with Jars of 1000 seconals and 1000 benzedrine in the late 40s when he was in highschool and comming back to the USA, getting jacked up and getting in fights with local marines.
I know these are hard questions to answer, like "describe the taste of a pear and compare it to an apple." Someone who does a great job of describing nuances of highs between drugs that are similar in structure are Alexander Shulgin and his friends in PIHKAL and other works. Especially in the "extension and comentary" section after the individual trip reports.
Food for thought: A friend I have thats in recovery that did some "creative cooking" a (long) while ago swears that adjusting the pH in one of the steps changes the subjective effects with one end of the spectrum being more stimulating and another more sex enhancing or something like this. Anyway may seem counterintuitive but I don't like to reject anecdotal info out of hand. And this underscores that there is a huge number of factors and variables that contribute to a drug's high.